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The map label for this gene is recD [H]

Identifier: 218550067

GI number: 218550067

Start: 2810777

End: 2812597

Strand: Reverse

Name: recD [H]

Synonym: EFER_2752

Alternate gene names: 218550067

Gene position: 2812597-2810777 (Counterclockwise)

Preceding gene: 218550068

Following gene: 218550065

Centisome position: 61.29

GC content: 52.72

Gene sequence:

>1821_bases
ATGAGCCTTCAAGAATTATTGCTGAGCGCCGTTGAGCAAAAATTTTTGCGTCCGTTGGATGCGCAATTTGCCCTGGCGGT
GGCCGGAGATAACGAGCCAGCTGTTGCGCTGGCGGCGGCCATCCTCAGCCATGATGCAGGTGAAGGGCATGTTTGCCTGC
CCCTTTCTCGCCTTGTTAACAGTGATGAGCCACATCCACTACTGGCAATGGGCTTCAACAAATTTGACGCGCCGCAAGAC
TGGCAAAACTGCCTGTTGGCGTCAGAAGCAGTAAGCCAGGGCGAACGACCCACACCGATGATTCTGCATGGTGATCGCCT
CTACCTGAATCGCATGTGGAGCAGTGAACGTACGGTGGCACGCTTTTTTAATGACGTAAATTACGCCATTGAAATTGATG
AGCCACTACTGACACAAACGCTGGAGCGACTCTTCCCTTCCACAGGTGAAATCAACTGGCAAAAAGTGGCCGCTGCGGTG
GCATTAACGCGGCGAATTTCGGTTATCTCTGGTGGTCCGGGAACGGGAAAAACCACAACAGTTGCAAAATTGCTGGCGGC
ACTGATTCAGATGATGGATGGCGAACGCTGCCGGATCCGCCTGGCTGCGCCGACAGGTAAAGCTGCTGCGAGGTTGACTG
AATCTTTGGGTAAAGCACTGCGCCAACTCCCGCTAACCGACGAGCAAAAGACGCGTATTCCTGATGATGCCAGCACGTTG
CACCGCTTGTTGGGTGCGCAACCGGGAAGCCAGCGTTTGCGTCATCATGCGGGAAACCCGTTGCATCTTGACGTACTGGT
AGTGGATGAAGCGTCAATGATCGATCTACCGATGATGTCGCGGTTGATCGAGGCTTTACCTCCTCATGCCAGGGTGATCT
TTCTGGGTGATCGCGATCAACTGGCTTCTGTAGAAGCAGGGGCCGTATTGGGTGATATCTGCGCCTGGGTCAGTGCTGGT
TTTACCGCACAGCGCGCACAGCAATTATCTCGCCTGACGGGATGTGAAATACCCGCAGGCAAGGGGACCGAAGCGGCATC
TTTACGAGACAGTCTCTGCCTGCTGCAAAAAAGTTACCGTTTTGGCAGCGATTCCGGGATTGGACAACTGGCTGCGGCGA
TTAATCGCGGAGACAAAACAGCCGTTCGTTCAATATTTCAACAGGAATTTAGCGATATCGAAAAACGCACGCTCACCAGT
AGCGAAGATTACAGCGCGATGCTGGAAGAGGCGATTGCTGGCTATGGTCGGTATCTGCAACTACTGCAACAACGTGCTGA
GCCGGAATCAATCATTCAGGCATTCAATGATTACCAGTTACTTTGCGCATTACGGGAAGGACCATTTGGCGTTGCCGGGC
TAAATGAACGACTGGAACACGTGTTACAGCAAAAACGTAAAATTCATCGCCACCCTCATTCCCGTTGGTACGAAGGGAGA
CCGGTAATGATTGCCCGCAACGACAGTCCATTAGGATTGTTTAATGGTGATATCGGCATAGCGCTTGATCGCGGGCAGGG
GATGCGAGTCTGGTTTGCAATGCCAGACGGAAGCATTAAATCGGTACAGCCCAGCCGTTTGCCGGAACACGAAACCACCT
GGGCGATGACGGTACATAAGTCGCAGGGGTCTGAGTTTAATCATGCAGCGCTGATTTTGCCCACTCAGCGTACGCCTGTT
GTGACAAGGGAACTGGTTTACACCGCAGTAACCCGCGCCCGTACACGCCTTTCGCTGTATACAGATGAACGCATTTTAAG
TAGTGCAATTGCTACCCGTACAGAGCGTCGTAGCGGACTTCCGGCATTGTTCAGAGTTTAA

Upstream 100 bases:

>100_bases
GCGATAATCCGCAGCAGGGCATTTATACCACCCGGCCCGATGGTGAACTCATAGCTCTGATGGACGACATGTTTGCAGGT
GCTGACGTAGAGGAAACACA

Downstream 100 bases:

>100_bases
ACGTCACATGTTGTGATAAATATTGACTGCCGGATAAGGCATTTATGCCACATCCGGCAGTTGTGCAGCGCCCCTTAAAA
GCCATCAACTCAACGCCCCC

Product: exonuclease V subunit alpha

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 606; Mature: 605

Protein sequence:

>606_residues
MSLQELLLSAVEQKFLRPLDAQFALAVAGDNEPAVALAAAILSHDAGEGHVCLPLSRLVNSDEPHPLLAMGFNKFDAPQD
WQNCLLASEAVSQGERPTPMILHGDRLYLNRMWSSERTVARFFNDVNYAIEIDEPLLTQTLERLFPSTGEINWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMMDGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKTRIPDDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIEALPPHARVIFLGDRDQLASVEAGAVLGDICAWVSAG
FTAQRAQQLSRLTGCEIPAGKGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVRSIFQQEFSDIEKRTLTS
SEDYSAMLEEAIAGYGRYLQLLQQRAEPESIIQAFNDYQLLCALREGPFGVAGLNERLEHVLQQKRKIHRHPHSRWYEGR
PVMIARNDSPLGLFNGDIGIALDRGQGMRVWFAMPDGSIKSVQPSRLPEHETTWAMTVHKSQGSEFNHAALILPTQRTPV
VTRELVYTAVTRARTRLSLYTDERILSSAIATRTERRSGLPALFRV

Sequences:

>Translated_606_residues
MSLQELLLSAVEQKFLRPLDAQFALAVAGDNEPAVALAAAILSHDAGEGHVCLPLSRLVNSDEPHPLLAMGFNKFDAPQD
WQNCLLASEAVSQGERPTPMILHGDRLYLNRMWSSERTVARFFNDVNYAIEIDEPLLTQTLERLFPSTGEINWQKVAAAV
ALTRRISVISGGPGTGKTTTVAKLLAALIQMMDGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKTRIPDDASTL
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIEALPPHARVIFLGDRDQLASVEAGAVLGDICAWVSAG
FTAQRAQQLSRLTGCEIPAGKGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVRSIFQQEFSDIEKRTLTS
SEDYSAMLEEAIAGYGRYLQLLQQRAEPESIIQAFNDYQLLCALREGPFGVAGLNERLEHVLQQKRKIHRHPHSRWYEGR
PVMIARNDSPLGLFNGDIGIALDRGQGMRVWFAMPDGSIKSVQPSRLPEHETTWAMTVHKSQGSEFNHAALILPTQRTPV
VTRELVYTAVTRARTRLSLYTDERILSSAIATRTERRSGLPALFRV
>Mature_605_residues
SLQELLLSAVEQKFLRPLDAQFALAVAGDNEPAVALAAAILSHDAGEGHVCLPLSRLVNSDEPHPLLAMGFNKFDAPQDW
QNCLLASEAVSQGERPTPMILHGDRLYLNRMWSSERTVARFFNDVNYAIEIDEPLLTQTLERLFPSTGEINWQKVAAAVA
LTRRISVISGGPGTGKTTTVAKLLAALIQMMDGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKTRIPDDASTLH
RLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIEALPPHARVIFLGDRDQLASVEAGAVLGDICAWVSAGF
TAQRAQQLSRLTGCEIPAGKGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVRSIFQQEFSDIEKRTLTSS
EDYSAMLEEAIAGYGRYLQLLQQRAEPESIIQAFNDYQLLCALREGPFGVAGLNERLEHVLQQKRKIHRHPHSRWYEGRP
VMIARNDSPLGLFNGDIGIALDRGQGMRVWFAMPDGSIKSVQPSRLPEHETTWAMTVHKSQGSEFNHAALILPTQRTPVV
TRELVYTAVTRARTRLSLYTDERILSSAIATRTERRSGLPALFRV

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=604, Percent_Identity=85.4304635761589, Blast_Score=1037, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 66716; Mature: 66585

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQELLLSAVEQKFLRPLDAQFALAVAGDNEPAVALAAAILSHDAGEGHVCLPLSRLVN
CCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEHHHHCC
SDEPHPLLAMGFNKFDAPQDWQNCLLASEAVSQGERPTPMILHGDRLYLNRMWSSERTVA
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEHHHCCCHHHHH
RFFNDVNYAIEIDEPLLTQTLERLFPSTGEINWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMMDGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKTRIPDDASTL
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIEALPPHARVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCHH
LASVEAGAVLGDICAWVSAGFTAQRAQQLSRLTGCEIPAGKGTEAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGQLAAAINRGDKTAVRSIFQQEFSDIEKRTLTSSEDYSAMLEEAIAGYGRYLQ
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLQQRAEPESIIQAFNDYQLLCALREGPFGVAGLNERLEHVLQQKRKIHRHPHSRWYEGR
HHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVMIARNDSPLGLFNGDIGIALDRGQGMRVWFAMPDGSIKSVQPSRLPEHETTWAMTVHK
EEEEEECCCCCEEECCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFNHAALILPTQRTPVVTRELVYTAVTRARTRLSLYTDERILSSAIATRTERRSGL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PALFRV
CHHHCC
>Mature Secondary Structure 
SLQELLLSAVEQKFLRPLDAQFALAVAGDNEPAVALAAAILSHDAGEGHVCLPLSRLVN
CHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEHHHHCC
SDEPHPLLAMGFNKFDAPQDWQNCLLASEAVSQGERPTPMILHGDRLYLNRMWSSERTVA
CCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEHHHCCCHHHHH
RFFNDVNYAIEIDEPLLTQTLERLFPSTGEINWQKVAAAVALTRRISVISGGPGTGKTTT
HHHHCCCEEEEECCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHEEEECCCCCCCHHH
VAKLLAALIQMMDGERCRIRLAAPTGKAAARLTESLGKALRQLPLTDEQKTRIPDDASTL
HHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHH
HRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDLPMMSRLIEALPPHARVIFLGDRDQ
HHHHCCCCCHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCHH
LASVEAGAVLGDICAWVSAGFTAQRAQQLSRLTGCEIPAGKGTEAASLRDSLCLLQKSYR
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHC
FGSDSGIGQLAAAINRGDKTAVRSIFQQEFSDIEKRTLTSSEDYSAMLEEAIAGYGRYLQ
CCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LLQQRAEPESIIQAFNDYQLLCALREGPFGVAGLNERLEHVLQQKRKIHRHPHSRWYEGR
HHHHHCCHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVMIARNDSPLGLFNGDIGIALDRGQGMRVWFAMPDGSIKSVQPSRLPEHETTWAMTVHK
EEEEEECCCCCEEECCCEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEC
SQGSEFNHAALILPTQRTPVVTRELVYTAVTRARTRLSLYTDERILSSAIATRTERRSGL
CCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PALFRV
CHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]