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The map label for this gene is dinB [H]

Identifier: 218550064

GI number: 218550064

Start: 2807097

End: 2808152

Strand: Reverse

Name: dinB [H]

Synonym: EFER_2749

Alternate gene names: 218550064

Gene position: 2808152-2807097 (Counterclockwise)

Preceding gene: 218550065

Following gene: 218550063

Centisome position: 61.2

GC content: 53.69

Gene sequence:

>1056_bases
ATGCGTAAAATCATTCATGTGGATATGGACTGCTTTTTCGCCGCGGTGGAGATGCGCGACAATCCCGCCCTGCGCGATAT
CCCTATTGCTATTGGCGGCAGCCGCGAACGTCGGGGGGTGATCAGCACCGCCAATTATCCCGCGCGTAAATTTGGCGTGC
GTAGCGCAATGCCAACCGGCATGGCGCTCAAGCTGTGTCCGCATCTCACCTTGCTTCCAGGGCGCTTTGACGCCTACAAA
GAAGCATCAAATCATATCCGCGAAATCTTCTCTCGCTACACATCGCGTATTGAGCCGCTGTCGCTGGATGAAGCTTATCT
CGACGTCACCGACAGCGTACATTGCCACGGTTCTGCGACCCTTATTGCTCAGGAAATCCGTCAGACGATTTTCAACGAGC
TGCAACTTACCGCCTCTGCGGGCGTTGCGCCGGTCAAGTTTCTCGCCAAAATCGCCTCAGACATGAATAAACCCAACGGT
CAGTTTGTGATTACGCCGGCAGAAGTTCCGGCATTTCTGCAAACCTTACCGCTGGCAAAAATTCCCGGTGTCGGCAAAGT
CTCGGCGGCAAAACTGGAAGCGATGGGGCTACGAACCTGCGGCGATGTACAAAAGTGTGATCTGGTGACATTGCTTAAAC
GCTTTGGCAAATTTGGCCGCATTTTGTGGGAGCGTAGTCAGGGCATTGACGAGCGCGACGTTAACAGCGAAAGGTTGCGA
AAATCCGTCGGTGTAGAACGCACGATGGCGGAAGATATTCATCACTGGTCTGAATGTGAAGCGATCATCGAGCGGTTGTA
TCCGGAACTTGAACGCCGTCTGGCAAAGGTAAAACCTGATTTGCTGATTGCCCGCCAGGGGGTGAAATTAAAGTTCGACG
ATTTTCAGCAAACCACTCAGGAACATGTCTGGCCGCGGCTGAATAAAGCTGACTTGATCGCCACTGCGCGTAAAACCTGG
GATGAACGCCGTGGCGGGCGCGGTGTGCGGCTGGTGGGGCTGCATGTGACGTTGCTGGATCCGCAAATGGAAAGACAACT
GGTGTTGGGATTATGA

Upstream 100 bases:

>100_bases
CAGCAGGTGCTTTCGCAACGAATGCGTTAAATGCTGAATCTTTACGCATTTCTCAAACCCTGAAATCACTGTATACTTTA
CCAGTGTTGAGAGGTGAGCA

Downstream 100 bases:

>100_bases
TGTATACTATTATGTATATTCTGGCGTGCATTATTATGAGGGTATCACTGTATGCATCGAATTCTTGCTGAAAAATCGGT
CAATATCACTGAGTTACGTA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKFGRILWERSQGIDERDVNSERLR
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTW
DERRGGRGVRLVGLHVTLLDPQMERQLVLGL

Sequences:

>Translated_351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKFGRILWERSQGIDERDVNSERLR
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTW
DERRGGRGVRLVGLHVTLLDPQMERQLVLGL
>Mature_351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYK
EASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKFGRILWERSQGIDERDVNSERLR
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTW
DERRGGRGVRLVGLHVTLLDPQMERQLVLGL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7705344, Length=356, Percent_Identity=33.4269662921348, Blast_Score=164, Evalue=1e-40,
Organism=Homo sapiens, GI84043967, Length=324, Percent_Identity=31.1728395061728, Blast_Score=158, Evalue=6e-39,
Organism=Homo sapiens, GI7706681, Length=325, Percent_Identity=31.3846153846154, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=32.6693227091633, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI5729982, Length=359, Percent_Identity=30.3621169916435, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=99.7150997150997, Blast_Score=721, Evalue=0.0,
Organism=Escherichia coli, GI1787432, Length=217, Percent_Identity=26.2672811059908, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI193205700, Length=406, Percent_Identity=32.0197044334975, Blast_Score=172, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17537959, Length=290, Percent_Identity=29.6551724137931, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI193205702, Length=351, Percent_Identity=27.6353276353276, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI115534089, Length=163, Percent_Identity=34.3558282208589, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=208, Percent_Identity=29.8076923076923, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI19923006, Length=327, Percent_Identity=31.8042813455657, Blast_Score=172, Evalue=3e-43,
Organism=Drosophila melanogaster, GI21355641, Length=356, Percent_Identity=29.2134831460674, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24644984, Length=356, Percent_Identity=29.2134831460674, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24668444, Length=121, Percent_Identity=35.5371900826446, Blast_Score=75, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39486; Mature: 39486

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTG
CCCEEEECHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCCHHHHCCHHCCCCC
MALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSAT
CHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCHH
LIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKFGRILWERSQGIDERDVNSERLR
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHH
EHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARKFGVRSAMPTG
CCCEEEECHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCEECCCCCHHHHCCHHCCCCC
MALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSLDEAYLDVTDSVHCHGSAT
CHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCHH
LIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNGQFVITPAEVPAFLQTLPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHCCHHH
IPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKFGRILWERSQGIDERDVNSERLR
CCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVERTMAEDIHHWSECEAIIERLYPELERRLAKVKPDLLIARQGVKLKFDDFQQTTQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEHHHHHHHH
EHVWPRLNKADLIATARKTWDERRGGRGVRLVGLHVTLLDPQMERQLVLGL
HHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEEECCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA