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The map label for this gene is tauC [H]

Identifier: 218549967

GI number: 218549967

Start: 2724285

End: 2725112

Strand: Reverse

Name: tauC [H]

Synonym: EFER_2652

Alternate gene names: 218549967

Gene position: 2725112-2724285 (Counterclockwise)

Preceding gene: 218549968

Following gene: 218549966

Centisome position: 59.39

GC content: 53.99

Gene sequence:

>828_bases
ATGAGTGTATTGATTAACGAGAAAACGCATCAGTGGCGCTGGCGACTGCGATGGCCTCTCTCGCGTCAGCTTACCTTAAG
TTTTAGCGTGTTAGCCGTTTTAGTGACTATCTGGTGGGCGGTGACAGCCTGTCAACTGATTAGCCCGCTGTTTCTGCCGC
CACCACAGCAAGTTTTGGCAAAACTGGTCACCATTGCCGGAGCGCAAGGATTTATGGATGCCACGCTATGGCAGCATTTG
GCCGCGAGTATGAGCCGTATTTTGCTGGCCTTGATCGCTGCGGTGGTTATCGGCATTCCGGCTGGAGTTGCAATGGGATT
AAGCCCAACGATACGCGGCATTCTCGATCCGATAATTGAGCTTTATCGCCCTGTACCACCACTCGCCTGGCTTCCTCTGA
TGGTTATCTGGTTCGGTATTGGCGAAACACCGAAAGTATTGTTGATCTGGTTGGCGATTTTCGCGCCCCTGACGATGTCA
GCCCTGGCGGGAGTTCAAAGCGTGCAACAGGTGCGCATTCGTGCCGCACAGTCACTGGGGGCGAATCGGGTTCAGGTATT
GTGGTACGTCATTTTACCTGGTGCTTTGCCGGAAATATTAACCGGGCTACGCATTGGACTTGGCGTTGGCTGGTCTACCC
TGGTGGCGGCAGAACTGATCGCGGCGACGCGAGGTTTAGGGTTTATGGTCCAGTCTGCCGGAGAATTTCTGGCAACTGAT
GTGGTGCTGGCGGGAATCGCGGTGATTGCGGTAATCGCCTTTCTTTTAGAGTTGAGTCTGCGCGCGTTACAGCGTCGCCT
GACGCCCTGGCATGGAGAAGTAAAATGA

Upstream 100 bases:

>100_bases
CTGCAGGAGAATCAAGCCGGGCGATTAAATCTGATCCGCAATTTATTGCGACCCGCGAATATGTCCTGAGCCGTGTGTTT
GCCCAACGGGAGGCGTTCTC

Downstream 100 bases:

>100_bases
GTGAACGTCTGAGTATTACCCCACTTGGGCCGCACATTGGCGCGTTGATTTCCGGCGCTGATTTCACGCGACCATTAAGT
GATAATCAGTTTGAACAGCT

Product: taurine transporter subunit

Products: taurine [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 274

Protein sequence:

>275_residues
MSVLINEKTHQWRWRLRWPLSRQLTLSFSVLAVLVTIWWAVTACQLISPLFLPPPQQVLAKLVTIAGAQGFMDATLWQHL
AASMSRILLALIAAVVIGIPAGVAMGLSPTIRGILDPIIELYRPVPPLAWLPLMVIWFGIGETPKVLLIWLAIFAPLTMS
ALAGVQSVQQVRIRAAQSLGANRVQVLWYVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAVIAFLLELSLRALQRRLTPWHGEVK

Sequences:

>Translated_275_residues
MSVLINEKTHQWRWRLRWPLSRQLTLSFSVLAVLVTIWWAVTACQLISPLFLPPPQQVLAKLVTIAGAQGFMDATLWQHL
AASMSRILLALIAAVVIGIPAGVAMGLSPTIRGILDPIIELYRPVPPLAWLPLMVIWFGIGETPKVLLIWLAIFAPLTMS
ALAGVQSVQQVRIRAAQSLGANRVQVLWYVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
VVLAGIAVIAVIAFLLELSLRALQRRLTPWHGEVK
>Mature_274_residues
SVLINEKTHQWRWRLRWPLSRQLTLSFSVLAVLVTIWWAVTACQLISPLFLPPPQQVLAKLVTIAGAQGFMDATLWQHLA
ASMSRILLALIAAVVIGIPAGVAMGLSPTIRGILDPIIELYRPVPPLAWLPLMVIWFGIGETPKVLLIWLAIFAPLTMSA
LAGVQSVQQVRIRAAQSLGANRVQVLWYVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATDV
VLAGIAVIAVIAFLLELSLRALQRRLTPWHGEVK

Specific function: Part of a binding-protein-dependent transport system for taurine. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0600

COG function: function code P; ABC-type nitrate/sulfonate/bicarbonate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786564, Length=275, Percent_Identity=85.0909090909091, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI87081802, Length=238, Percent_Identity=34.453781512605, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1789033, Length=172, Percent_Identity=30.8139534883721, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29886; Mature: 29755

Theoretical pI: Translated: 11.35; Mature: 11.35

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINEKTHQWRWRLRWPLSRQLTLSFSVLAVLVTIWWAVTACQLISPLFLPPPQQVLA
CCEEECCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLVTIAGAQGFMDATLWQHLAASMSRILLALIAAVVIGIPAGVAMGLSPTIRGILDPIIE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAWLPLMVIWFGIGETPKVLLIWLAIFAPLTMSALAGVQSVQQVRIRAAQSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANRVQVLWYVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAVIAFLLELSLRALQRRLTPWHGEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SVLINEKTHQWRWRLRWPLSRQLTLSFSVLAVLVTIWWAVTACQLISPLFLPPPQQVLA
CEEECCCCHHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
KLVTIAGAQGFMDATLWQHLAASMSRILLALIAAVVIGIPAGVAMGLSPTIRGILDPIIE
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHH
LYRPVPPLAWLPLMVIWFGIGETPKVLLIWLAIFAPLTMSALAGVQSVQQVRIRAAQSLG
HHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANRVQVLWYVILPGALPEILTGLRIGLGVGWSTLVAAELIAATRGLGFMVQSAGEFLATD
CCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
VVLAGIAVIAVIAFLLELSLRALQRRLTPWHGEVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: taurine [Periplasm]; ATP; H2O [C]

Specific reaction: taurine [Periplasm] + ATP + H2O = taurine [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503 [H]