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The map label for this gene is pobR [H]

Identifier: 218549906

GI number: 218549906

Start: 2660855

End: 2661613

Strand: Reverse

Name: pobR [H]

Synonym: EFER_2591

Alternate gene names: 218549906

Gene position: 2661613-2660855 (Counterclockwise)

Preceding gene: 218549914

Following gene: 218549905

Centisome position: 58.0

GC content: 49.67

Gene sequence:

>759_bases
ATGCAAAACCAGATACATCAGCGGGATTTGATCGTTGGTCTGCAAAAGGGGCTGGCGCTGATTCAACTTTTCTCTAAGGA
ATTTCCTCGATTAACTGTTCCTCAGGCGGCAAAACTGAGCGGATTAACGCAAAGTGCGACAAGGCGCTTTTTCCTGACGC
TGGTCCATGAACGTTATCTGAATACCGATGGGCGGTATTACTGGCTTACAGCCCGAACACTGCGGCTCGGTCAGGCGTAT
GTGGACTCCGCTCAATTTCCAAAGATGGTGAGGCCGATAGTTGAGTACGTCGCCAGTCGTAGCGAAGAACATGCGTCAGT
GGGGGTTATTGATGACGACGAGTTGGTTTATATCGCCCGTAGCAAACATACGCCGTTTAATTCAACCTCAGTACGTCTGG
GTGAGCGTGTGCCCATCCATTGTACAGCCGGAGGCCGGTTATGGCTGGCTTCCCTTGATGAAGCCGAATGTGAAATGGTG
CTACGGCGCATTCGATGTGAGCAAAGAACGCCATATACAGTGACGGATATTCAGCTGCTAAAGGCAAAAATTGCTGAAGT
TCGAGAGTTGGGCTACGCCACCGTTGAGCAGGAATTTGAGATTGGCATGTTGGTGATTGCTGTACCGCTAATCGACAGAG
AAGGACAATACTGGGGAGCGCTAAGCCTGACCAGTCATCAGTCCAGAACTTCAATCGAAAAGTTGTGTCGTGATCATTTG
GATCTTCTCTACAGTGCCCAGGCGATGTTGTTTGGTTAA

Upstream 100 bases:

>100_bases
AGAGCAGCAATGCAGAATTCGGACAGCTTGCCTGTTAATCGCACCACCATTGCGATAATCGCGCTACAATTACTTTTTTG
TTGCGAAAATGTGAACTGCT

Downstream 100 bases:

>100_bases
AAGGCTAAATAATTATATTATTGTGTGAAAATAATTTTTTATCAAAGGACTGAGTTAAATGTTTGTGAAGTTTAAAAGAT
TGGTGTTAATCGTTCCTTTT

Product: Regulatory proteins, IclR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MQNQIHQRDLIVGLQKGLALIQLFSKEFPRLTVPQAAKLSGLTQSATRRFFLTLVHERYLNTDGRYYWLTARTLRLGQAY
VDSAQFPKMVRPIVEYVASRSEEHASVGVIDDDELVYIARSKHTPFNSTSVRLGERVPIHCTAGGRLWLASLDEAECEMV
LRRIRCEQRTPYTVTDIQLLKAKIAEVRELGYATVEQEFEIGMLVIAVPLIDREGQYWGALSLTSHQSRTSIEKLCRDHL
DLLYSAQAMLFG

Sequences:

>Translated_252_residues
MQNQIHQRDLIVGLQKGLALIQLFSKEFPRLTVPQAAKLSGLTQSATRRFFLTLVHERYLNTDGRYYWLTARTLRLGQAY
VDSAQFPKMVRPIVEYVASRSEEHASVGVIDDDELVYIARSKHTPFNSTSVRLGERVPIHCTAGGRLWLASLDEAECEMV
LRRIRCEQRTPYTVTDIQLLKAKIAEVRELGYATVEQEFEIGMLVIAVPLIDREGQYWGALSLTSHQSRTSIEKLCRDHL
DLLYSAQAMLFG
>Mature_252_residues
MQNQIHQRDLIVGLQKGLALIQLFSKEFPRLTVPQAAKLSGLTQSATRRFFLTLVHERYLNTDGRYYWLTARTLRLGQAY
VDSAQFPKMVRPIVEYVASRSEEHASVGVIDDDELVYIARSKHTPFNSTSVRLGERVPIHCTAGGRLWLASLDEAECEMV
LRRIRCEQRTPYTVTDIQLLKAKIAEVRELGYATVEQEFEIGMLVIAVPLIDREGQYWGALSLTSHQSRTSIEKLCRDHL
DLLYSAQAMLFG

Specific function: Positive regulator of the pobA gene for p- hydroxybenzoate hydroxylase [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1786468, Length=230, Percent_Identity=27.8260869565217, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI87082359, Length=226, Percent_Identity=23.4513274336283, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788131, Length=242, Percent_Identity=25.6198347107438, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1786715, Length=218, Percent_Identity=24.7706422018349, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789999, Length=221, Percent_Identity=25.3393665158371, Blast_Score=68, Evalue=7e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012794
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28728; Mature: 28728

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNQIHQRDLIVGLQKGLALIQLFSKEFPRLTVPQAAKLSGLTQSATRRFFLTLVHERYL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHC
NTDGRYYWLTARTLRLGQAYVDSAQFPKMVRPIVEYVASRSEEHASVGVIDDDELVYIAR
CCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECEECCCCEEEEEE
SKHTPFNSTSVRLGERVPIHCTAGGRLWLASLDEAECEMVLRRIRCEQRTPYTVTDIQLL
CCCCCCCCCCEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
KAKIAEVRELGYATVEQEFEIGMLVIAVPLIDREGQYWGALSLTSHQSRTSIEKLCRDHL
HHHHHHHHHCCHHHHHHHHCCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
DLLYSAQAMLFG
HHHHHHHHHHCC
>Mature Secondary Structure
MQNQIHQRDLIVGLQKGLALIQLFSKEFPRLTVPQAAKLSGLTQSATRRFFLTLVHERYL
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHC
NTDGRYYWLTARTLRLGQAYVDSAQFPKMVRPIVEYVASRSEEHASVGVIDDDELVYIAR
CCCCCEEEEEEHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCEECEECCCCEEEEEE
SKHTPFNSTSVRLGERVPIHCTAGGRLWLASLDEAECEMVLRRIRCEQRTPYTVTDIQLL
CCCCCCCCCCEEECCCCCEEECCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHHH
KAKIAEVRELGYATVEQEFEIGMLVIAVPLIDREGQYWGALSLTSHQSRTSIEKLCRDHL
HHHHHHHHHCCHHHHHHHHCCCEEEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHH
DLLYSAQAMLFG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8331077 [H]