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The map label for this gene is hokE [H]

Identifier: 218549842

GI number: 218549842

Start: 2591381

End: 2591632

Strand: Reverse

Name: hokE [H]

Synonym: EFER_2525

Alternate gene names: 218549842

Gene position: 2591632-2591381 (Counterclockwise)

Preceding gene: 218549843

Following gene: 218549841

Centisome position: 56.48

GC content: 48.81

Gene sequence:

>252_bases
ATGAAGCCCCAGGAGATATTTCTATCAACCCTGGGGCTGCCACTCCAAACCCGAACAATTTGGATGGTAGCCCCTTCTTC
GCATGGAGGCAATATAAACATGCTGACGAAATATGCCCTTGTGGCAGTCATAGTGCTGTGTTTGACGGTGCTGGGATTTA
CGCTTCTGGTCGGCGACTCGCTGTGTGAGTTTACGGTGAAGGAACGTAATATTGAGTTTAAGGCTGTTCTCGCTTACGAA
CCGAAGAAGTAG

Upstream 100 bases:

>100_bases
ACTAACTGTATAAATAAACAGCTATTTTGCTAAGGAAGGGTAAGATGACTGCGGGTGCCTGAAGCTTTCCGGTTTCAGGT
TTACTCTGAGGTCTGGAAAG

Downstream 100 bases:

>100_bases
CCGTTGTGCGGGGAGCAATCCCCGCATATCCGGTTGTCAGGTCAGGATGGTAAGGCACCTGCTTTACACTTTCGCCCGCG
GTCAGTGATGGCTGCGGGCG

Product: small toxic membrane polypeptide, HokE-like protein (partial)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 83; Mature: 83

Protein sequence:

>83_residues
MKPQEIFLSTLGLPLQTRTIWMVAPSSHGGNINMLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK

Sequences:

>Translated_83_residues
MKPQEIFLSTLGLPLQTRTIWMVAPSSHGGNINMLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK
>Mature_83_residues
MKPQEIFLSTLGLPLQTRTIWMVAPSSHGGNINMLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYE
PKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hok/gef family [H]

Homologues:

Organism=Escherichia coli, GI48994879, Length=50, Percent_Identity=98, Blast_Score=99, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000021
- InterPro:   IPR018084
- ProDom:   PD005979 [H]

Pfam domain/function: PF01848 HOK_GEF [H]

EC number: NA

Molecular weight: Translated: 9212; Mature: 9212

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS00556 HOK_GEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPQEIFLSTLGLPLQTRTIWMVAPSSHGGNINMLTKYALVAVIVLCLTVLGFTLLVGDS
CCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LCEFTVKERNIEFKAVLAYEPKK
HHHEEECCCCCEEEEEEEECCCC
>Mature Secondary Structure
MKPQEIFLSTLGLPLQTRTIWMVAPSSHGGNINMLTKYALVAVIVLCLTVLGFTLLVGDS
CCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCH
LCEFTVKERNIEFKAVLAYEPKK
HHHEEECCCCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]