Click here to switch to the map view.

The map label for this gene is fepE [H]

Identifier: 218549825

GI number: 218549825

Start: 2569815

End: 2570990

Strand: Reverse

Name: fepE [H]

Synonym: EFER_2507

Alternate gene names: 218549825

Gene position: 2570990-2569815 (Counterclockwise)

Preceding gene: 218549826

Following gene: 218549821

Centisome position: 56.03

GC content: 42.43

Gene sequence:

>1176_bases
TTGTGCTTTTATAGACTCAAACCTCAGGTTTCACACATGTCATCATTAAATGTAAATCGAGAAAAAGACTCGGATTTCGT
CGGCTATGCATTACCTTCGCCTGACAGAAATGAAATAGATTTATTACATCTTATTGACGTTCTTTGGCGGGCAAAGAAGC
AAATTATTGCCATTAGTTTTGCATTTGCTTGTGCCGGAATATTAATTTCCTTTTTGTTGCCACAAAAATGGACCAGTGCA
GCGGTAGTCACTCCTGCAGAAGCCGTGCAGTGGCAGGAACTGGAAAGAACATTTACCAAATTACGTGTACTGGATGTCGA
CGCTGGTATTGATCGTAGCAGCGTATTTAACCTTTTTATTAAGAAGTTTCAATCTCCTACACTGCTGGAAGATTATCTCC
GCTCCTCACCTTATGTTATGGATCAACTGAAAGGAGCTGAAATTGATGAACTGGAGTTACACCGGGCTATTGTTGCGCTC
AGCGAGAAAATGAAAGCGGTGGATGAGAACTCCAGCAAGAAGAAAGATGAAACTGCGCTCTATACTGCCTGGCGTTTAAG
CTTTACTGCACCGACAAAAGAAGAAGCACAGCAGGTTCTGGCAGGTTATATCCAGTATATTTCCAATCTGGTGGTTACAG
AATCACTGGAGAATATCCGTAATAAACTGGAAATTAAAACCCGTTTTGAGCAAGAAAAACTGGCTCAGGATCGTGTGAAA
ATACGTAATCAGTTGGATGCAAATATTCAACGACTGAATTATTCGCTCGACATTGCCAACGCTGCCGGGATTAAAAAACC
AGTTTATAGCAACGGACAGGCAGTAAAAGACGATCCAGAATTTTCAATTTCTCTCGGTGCCGATGGTATTCAGCGTAAAC
TGGAAATCGAAAAAGGCGTTACAGACGTAGCCGAACTGAATGGCGATTTGCGTAATCGACAGTATTACGTAGAGCAACTC
AAAAAGCTGAATGTTAGCGATGTCAAATTTTCACCGTTTAAATATCAGATGAAACCATCATTGCCGGTGAAGAAAGATGG
TCCGGGGAGAGCGATTATTGCCATTCTGGCAGCGCTTGTGGGTGGAATGGTTGCTTGTGGTAGTGTACTGATGCGTAACG
CCATGCTTTCTCGCAAGATGGAGAAAGCCATTACGGTAGATGAACAGTTAGTGTGA

Upstream 100 bases:

>100_bases
ATTGCTGGGGTTGCTGAGTTTGCTACTCATTTTGGGGTAAAAATAGTGAAAGAGTTCTTTCGGATAATTCTCAGATCCTG
TTAGAATATTATATTCACCG

Downstream 100 bases:

>100_bases
TGACAACCGGGGAGCGGTAATGCGCTCCCTTTTTTCATTTTTTATTTCTCCCGAGCGGCACTACAAGCGGTGTTCCGGCT
ACCGGATCGTCAATTATCAT

Product: ferric enterobactin transport protein FepE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MCFYRLKPQVSHMSSLNVNREKDSDFVGYALPSPDRNEIDLLHLIDVLWRAKKQIIAISFAFACAGILISFLLPQKWTSA
AVVTPAEAVQWQELERTFTKLRVLDVDAGIDRSSVFNLFIKKFQSPTLLEDYLRSSPYVMDQLKGAEIDELELHRAIVAL
SEKMKAVDENSSKKKDETALYTAWRLSFTAPTKEEAQQVLAGYIQYISNLVVTESLENIRNKLEIKTRFEQEKLAQDRVK
IRNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPEFSISLGADGIQRKLEIEKGVTDVAELNGDLRNRQYYVEQL
KKLNVSDVKFSPFKYQMKPSLPVKKDGPGRAIIAILAALVGGMVACGSVLMRNAMLSRKMEKAITVDEQLV

Sequences:

>Translated_391_residues
MCFYRLKPQVSHMSSLNVNREKDSDFVGYALPSPDRNEIDLLHLIDVLWRAKKQIIAISFAFACAGILISFLLPQKWTSA
AVVTPAEAVQWQELERTFTKLRVLDVDAGIDRSSVFNLFIKKFQSPTLLEDYLRSSPYVMDQLKGAEIDELELHRAIVAL
SEKMKAVDENSSKKKDETALYTAWRLSFTAPTKEEAQQVLAGYIQYISNLVVTESLENIRNKLEIKTRFEQEKLAQDRVK
IRNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPEFSISLGADGIQRKLEIEKGVTDVAELNGDLRNRQYYVEQL
KKLNVSDVKFSPFKYQMKPSLPVKKDGPGRAIIAILAALVGGMVACGSVLMRNAMLSRKMEKAITVDEQLV
>Mature_391_residues
MCFYRLKPQVSHMSSLNVNREKDSDFVGYALPSPDRNEIDLLHLIDVLWRAKKQIIAISFAFACAGILISFLLPQKWTSA
AVVTPAEAVQWQELERTFTKLRVLDVDAGIDRSSVFNLFIKKFQSPTLLEDYLRSSPYVMDQLKGAEIDELELHRAIVAL
SEKMKAVDENSSKKKDETALYTAWRLSFTAPTKEEAQQVLAGYIQYISNLVVTESLENIRNKLEIKTRFEQEKLAQDRVK
IRNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPEFSISLGADGIQRKLEIEKGVTDVAELNGDLRNRQYYVEQL
KKLNVSDVKFSPFKYQMKPSLPVKKDGPGRAIIAILAALVGGMVACGSVLMRNAMLSRKMEKAITVDEQLV

Specific function: Part of the ferric enterobactin transport system [H]

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI1786802, Length=369, Percent_Identity=78.5907859078591, Blast_Score=607, Evalue=1e-175,
Organism=Escherichia coli, GI87082029, Length=351, Percent_Identity=27.6353276353276, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI87082332, Length=353, Percent_Identity=23.5127478753541, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 44109; Mature: 44109

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCFYRLKPQVSHMSSLNVNREKDSDFVGYALPSPDRNEIDLLHLIDVLWRAKKQIIAISF
CCEEECCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AFACAGILISFLLPQKWTSAAVVTPAEAVQWQELERTFTKLRVLDVDAGIDRSSVFNLFI
HHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
KKFQSPTLLEDYLRSSPYVMDQLKGAEIDELELHRAIVALSEKMKAVDENSSKKKDETAL
HHHCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHE
YTAWRLSFTAPTKEEAQQVLAGYIQYISNLVVTESLENIRNKLEIKTRFEQEKLAQDRVK
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPEFSISLGADGIQRKLEIEKGV
HHHHHCCHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCC
TDVAELNGDLRNRQYYVEQLKKLNVSDVKFSPFKYQMKPSLPVKKDGPGRAIIAILAALV
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHH
GGMVACGSVLMRNAMLSRKMEKAITVDEQLV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC
>Mature Secondary Structure
MCFYRLKPQVSHMSSLNVNREKDSDFVGYALPSPDRNEIDLLHLIDVLWRAKKQIIAISF
CCEEECCCHHHHHHHCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
AFACAGILISFLLPQKWTSAAVVTPAEAVQWQELERTFTKLRVLDVDAGIDRSSVFNLFI
HHHHHHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHH
KKFQSPTLLEDYLRSSPYVMDQLKGAEIDELELHRAIVALSEKMKAVDENSSKKKDETAL
HHHCCCHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHE
YTAWRLSFTAPTKEEAQQVLAGYIQYISNLVVTESLENIRNKLEIKTRFEQEKLAQDRVK
EEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IRNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPEFSISLGADGIQRKLEIEKGV
HHHHHCCHHHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHCC
TDVAELNGDLRNRQYYVEQLKKLNVSDVKFSPFKYQMKPSLPVKKDGPGRAIIAILAALV
HHHHHHCCHHHHHHHHHHHHHHCCCCCEEECCEEEEECCCCCCCCCCCCHHHHHHHHHHH
GGMVACGSVLMRNAMLSRKMEKAITVDEQLV
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 1826089 [H]