| Definition | Escherichia fergusonii ATCC 35469 chromosome, complete genome. |
|---|---|
| Accession | NC_011740 |
| Length | 4,588,711 |
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The map label for this gene is entA [H]
Identifier: 218549816
GI number: 218549816
Start: 2560068
End: 2560814
Strand: Reverse
Name: entA [H]
Synonym: EFER_2498
Alternate gene names: 218549816
Gene position: 2560814-2560068 (Counterclockwise)
Preceding gene: 218549817
Following gene: 218549815
Centisome position: 55.81
GC content: 57.83
Gene sequence:
>747_bases ATGGATTTCAGCGGCAAAAATGTCTGGGTAACCGGTGCGGGGAAAGGTATTGGCTACGCCACGGCGCTGGCATTTGTTGA GGCCGGAGCGAAAGTTACAGGTTTTGATCAAGCGTTCACTCTGGAGCAATATCCCTTTGCGACCGAAGTAATGGATGTAG CCGACGCTGCGCAGGTGGCGCAAGTGTGTCAGCGACTGTTAGCGCAAACGGAGCGACTGGACGTGCTGGTCAATGCGGCG GGAATTTTGCGCATGGGCGCGACCGATCAGCTCAGCAAGGAGGACTGGCAGCAGACTTTTTCGGTTAACGTCGGCGGTGC GTTTAACCTGTTCCAGCAAACCATGAACCAGTTTCGCCGTCAGCGGGGCGGGGCGATTGTCACTGTGGCGTCCGACGCCG CACACACGCCGCGTATTGGTATGAGTGCTTATGGCGCGTCGAAAGCGGCGCTGAAAAGCCTGGCGTTGAGCGTCGGGCTG GAACTGGCGGGTAGCGGTGTGCGCTGTAATGTGGTTTCCCCGGGGTCCACCGACACCGATATGCAACGCACGCTGTGGGT GAGTGATGACGCCGAAGAGCAGCGTATTCGCGGCTTTGGCGAGCAGTTTAAACTCGGCATTCCGCTGGGGAAAATCGCCC GTCCACAAGAGATCGCCAACACGATTTTGTTCCTCGCCTCTGACCTCGCCAGCCATATCACCCTACAGGATATTGTGGTA GATGGCGGCTCAACACTGGGGGCATAA
Upstream 100 bases:
>100_bases CGCGCTGGCGCAAAGTGCATGGCGATATCGATTTTGTCATGCTGGCGAAAAATCCGACCATCGATGCCTGGTGGAAGCTA CTCTCCCGCGAGGTGAAATG
Downstream 100 bases:
>100_bases GCATGATCTGGAAACGCCATTTAACGCTCGACGAACTGAACGCCACCAGCGATAACACAATGGTGGCGCATCTGGGAATT GTTTATACCCGTCTAGGCGA
Product: 2,3-dihydroxybenzoate-2,3-dehydrogenase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTLEQYPFATEVMDVADAAQVAQVCQRLLAQTERLDVLVNAA GILRMGATDQLSKEDWQQTFSVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA
Sequences:
>Translated_248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTLEQYPFATEVMDVADAAQVAQVCQRLLAQTERLDVLVNAA GILRMGATDQLSKEDWQQTFSVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA >Mature_248_residues MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTLEQYPFATEVMDVADAAQVAQVCQRLLAQTERLDVLVNAA GILRMGATDQLSKEDWQQTFSVNVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV DGGSTLGA
Specific function: Siderophore biosynthesis; enterobactin biosynthesis. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI66933014, Length=251, Percent_Identity=32.2709163346614, Blast_Score=110, Evalue=1e-24, Organism=Homo sapiens, GI32483357, Length=259, Percent_Identity=30.8880308880309, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=3e-19, Organism=Homo sapiens, GI7705925, Length=248, Percent_Identity=31.0483870967742, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI40254992, Length=195, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI15277342, Length=257, Percent_Identity=29.5719844357977, Blast_Score=84, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=208, Percent_Identity=30.7692307692308, Blast_Score=82, Evalue=4e-16, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=24.8062015503876, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI126723750, Length=265, Percent_Identity=26.0377358490566, Blast_Score=79, Evalue=5e-15, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.7460317460317, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI10190704, Length=256, Percent_Identity=24.609375, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI31542939, Length=250, Percent_Identity=28.4, Blast_Score=74, Evalue=8e-14, Organism=Homo sapiens, GI59889578, Length=231, Percent_Identity=27.7056277056277, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI4503817, Length=236, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=6e-11, Organism=Homo sapiens, GI4758504, Length=197, Percent_Identity=31.4720812182741, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1786812, Length=248, Percent_Identity=98.3870967741936, Blast_Score=496, Evalue=1e-142, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=36, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=31.25, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI1788459, Length=249, Percent_Identity=29.3172690763052, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=27.6, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=25.6916996047431, Blast_Score=91, Evalue=7e-20, Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=31.8897637795276, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1787905, Length=254, Percent_Identity=28.3464566929134, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1789378, Length=264, Percent_Identity=27.2727272727273, Blast_Score=86, Evalue=2e-18, Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=27.8625954198473, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=29.9595141700405, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI1787820, Length=176, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1786701, Length=206, Percent_Identity=25.7281553398058, Blast_Score=60, Evalue=1e-10, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=34.7169811320755, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=33.2, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17562990, Length=261, Percent_Identity=34.8659003831418, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI193204405, Length=266, Percent_Identity=34.9624060150376, Blast_Score=110, Evalue=7e-25, Organism=Caenorhabditis elegans, GI72000259, Length=262, Percent_Identity=35.1145038167939, Blast_Score=110, Evalue=8e-25, Organism=Caenorhabditis elegans, GI17563726, Length=262, Percent_Identity=33.587786259542, Blast_Score=107, Evalue=6e-24, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.4347826086957, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=35.9550561797753, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17531453, Length=265, Percent_Identity=33.2075471698113, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17560220, Length=263, Percent_Identity=34.2205323193916, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=29.2134831460674, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=32.5757575757576, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17562904, Length=264, Percent_Identity=31.4393939393939, Blast_Score=98, Evalue=4e-21, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=29.7959183673469, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=29.4820717131474, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=29.811320754717, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI25147288, Length=253, Percent_Identity=27.6679841897233, Blast_Score=87, Evalue=6e-18, Organism=Caenorhabditis elegans, GI17562910, Length=264, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=7e-18, Organism=Caenorhabditis elegans, GI71994604, Length=250, Percent_Identity=30.8, Blast_Score=86, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=29.7619047619048, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17508651, Length=194, Percent_Identity=29.8969072164948, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17551412, Length=269, Percent_Identity=28.996282527881, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30.7407407407407, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=28.4644194756554, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=30.6818181818182, Blast_Score=78, Evalue=4e-15, Organism=Caenorhabditis elegans, GI212645366, Length=247, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17536651, Length=260, Percent_Identity=30, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538182, Length=232, Percent_Identity=29.7413793103448, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17568967, Length=205, Percent_Identity=30.7317073170732, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI193207185, Length=148, Percent_Identity=36.4864864864865, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17538486, Length=263, Percent_Identity=28.1368821292776, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=28.7179487179487, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17536025, Length=260, Percent_Identity=30, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17564282, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17561272, Length=240, Percent_Identity=25, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322227, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=9e-14, Organism=Saccharomyces cerevisiae, GI6323882, Length=219, Percent_Identity=27.8538812785388, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6322861, Length=191, Percent_Identity=27.7486910994764, Blast_Score=71, Evalue=2e-13, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=23.7354085603113, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI24644339, Length=254, Percent_Identity=33.4645669291339, Blast_Score=108, Evalue=4e-24, Organism=Drosophila melanogaster, GI23397609, Length=249, Percent_Identity=34.136546184739, Blast_Score=105, Evalue=4e-23, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=33.3333333333333, Blast_Score=104, Evalue=6e-23, Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=32.4110671936759, Blast_Score=101, Evalue=4e-22, Organism=Drosophila melanogaster, GI24639444, Length=253, Percent_Identity=31.6205533596838, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=30.7086614173228, Blast_Score=99, Evalue=4e-21, Organism=Drosophila melanogaster, GI21355319, Length=257, Percent_Identity=28.4046692607004, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24644337, Length=255, Percent_Identity=30.1960784313725, Blast_Score=91, Evalue=8e-19, Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=32.1052631578947, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI21356301, Length=190, Percent_Identity=28.9473684210526, Blast_Score=71, Evalue=5e-13, Organism=Drosophila melanogaster, GI24665243, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI221331218, Length=216, Percent_Identity=28.2407407407407, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24665247, Length=217, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI221331216, Length=217, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=4e-12, Organism=Drosophila melanogaster, GI17737361, Length=236, Percent_Identity=29.2372881355932, Blast_Score=67, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR003560 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.3.1.28 [H]
Molecular weight: Translated: 26278; Mature: 26278
Theoretical pI: Translated: 4.85; Mature: 4.85
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTLEQYPFATEVMDVADAAQVA CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHH QVCQRLLAQTERLDVLVNAAGILRMGATDQLSKEDWQQTFSVNVGGAFNLFQQTMNQFRR HHHHHHHHHHHHHHHHEECHHHEEECCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHH QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD HHCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV CHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEE DGGSTLGA ECCCCCCC >Mature Secondary Structure MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFTLEQYPFATEVMDVADAAQVA CCCCCCEEEEEECCCCCHHHHHHHHHHCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHH QVCQRLLAQTERLDVLVNAAGILRMGATDQLSKEDWQQTFSVNVGGAFNLFQQTMNQFRR HHHHHHHHHHHHHHHHEECHHHEEECCCCCCCHHHHHHHHEECCCCHHHHHHHHHHHHHH QRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTDTD HHCCEEEEEECCCCCCCCCCCHHCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCC MQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLASHITLQDIVV CHHEEEECCCHHHHHHHCCCCCEEECCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEE DGGSTLGA ECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 2521622; 2521621; 9278503 [H]