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The map label for this gene is ybeM [H]

Identifier: 218549797

GI number: 218549797

Start: 2541518

End: 2542381

Strand: Reverse

Name: ybeM [H]

Synonym: EFER_2478

Alternate gene names: 218549797

Gene position: 2542381-2541518 (Counterclockwise)

Preceding gene: 218549799

Following gene: 218549796

Centisome position: 55.41

GC content: 51.5

Gene sequence:

>864_bases
TTGATTTGTATAACTGATGAGTTTAACGCCGTTTATTCATCTTTGGCGAGTCTGATAAATCAGGCAGGAGGGATTATGCT
GGTTGCCGCAGGGCAGTTTGCCGTTTCACCCGTATGGGAAAGGAACGCAGAAACATGTGTATCGTTGATGGAGCAGGCCG
CCGAAAGCGATGTCTCTCTGCTAGTTTTGCCGGAGGCGTTGTTGGCTCGGGATGATCTTGATCCAGATTTGGCGGTGAAG
TCCGCTCAACCTGTTGAAGGGGATTTTCTTGCACGGTTACTACGCGAGAGCAAACGTAACACGATGACTACTGTGCTGGC
GATACATGTGCCTTCAGTTCCTGGCAGGGCGTTCAATATGCTGGTCGCGCTGCAAAGAGGAAAAATTATTGCCCGGTATG
CCAAGTTGCATCTCTATGATGCTTTTGCCATCCAGGAATCACGCAATGTTGATGCAGGAAAATCACTACCACCATTACTG
GATGTTGACGGAATGAAGGTTGGGCTGATGACGTGCTACGATTTACGCTTTCCTGAACTGGCGTTGGCCCATGCGTTGCA
AGGAGCAGAAATATTGGTCCTGCCGGCAGCCTGGGTGCGTGGTGCGCTGAAAGAACATCACTGGTCCACACTGCTGGCGG
CACGGGCGCTGGATACTACCTGTTACATGGTCGCTGCGGGGGAGTGTGGAACACGCAATATTGGGCAAAGCCGTATTATT
GATCCTTTTGGCGTTACGCTTGCAGCCGCAGCAGAAATACCTGCATTGATTATTGCTGATATATCCGCTGAGCGCGTTCG
CCAGGTCAGGGCACAATTGCCCGTTTTAGCCAACCGCCGATTTGCGCCACCGCAATTGCTGTGA

Upstream 100 bases:

>100_bases
GGGGTTAAAGCGCATACTCAACATCCATCTCGCCACGCTACCTGTTCCACCGCCAATAAAAACTGCTAAAAGAAGTTGTA
ACACTGCAAAATCCTGCTAT

Downstream 100 bases:

>100_bases
TGTTTTTTTAAACAATGCTTGATTCACCTTGTTACAGATTGCTATTGTGTGCGCGCGTCGAATGACCGTTAATATTCTCA
GGGTTTATAGGCGTGATTTG

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MICITDEFNAVYSSLASLINQAGGIMLVAAGQFAVSPVWERNAETCVSLMEQAAESDVSLLVLPEALLARDDLDPDLAVK
SAQPVEGDFLARLLRESKRNTMTTVLAIHVPSVPGRAFNMLVALQRGKIIARYAKLHLYDAFAIQESRNVDAGKSLPPLL
DVDGMKVGLMTCYDLRFPELALAHALQGAEILVLPAAWVRGALKEHHWSTLLAARALDTTCYMVAAGECGTRNIGQSRII
DPFGVTLAAAAEIPALIIADISAERVRQVRAQLPVLANRRFAPPQLL

Sequences:

>Translated_287_residues
MICITDEFNAVYSSLASLINQAGGIMLVAAGQFAVSPVWERNAETCVSLMEQAAESDVSLLVLPEALLARDDLDPDLAVK
SAQPVEGDFLARLLRESKRNTMTTVLAIHVPSVPGRAFNMLVALQRGKIIARYAKLHLYDAFAIQESRNVDAGKSLPPLL
DVDGMKVGLMTCYDLRFPELALAHALQGAEILVLPAAWVRGALKEHHWSTLLAARALDTTCYMVAAGECGTRNIGQSRII
DPFGVTLAAAAEIPALIIADISAERVRQVRAQLPVLANRRFAPPQLL
>Mature_287_residues
MICITDEFNAVYSSLASLINQAGGIMLVAAGQFAVSPVWERNAETCVSLMEQAAESDVSLLVLPEALLARDDLDPDLAVK
SAQPVEGDFLARLLRESKRNTMTTVLAIHVPSVPGRAFNMLVALQRGKIIARYAKLHLYDAFAIQESRNVDAGKSLPPLL
DVDGMKVGLMTCYDLRFPELALAHALQGAEILVLPAAWVRGALKEHHWSTLLAARALDTTCYMVAAGECGTRNIGQSRII
DPFGVTLAAAAEIPALIIADISAERVRQVRAQLPVLANRRFAPPQLL

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632350, Length=277, Percent_Identity=35.3790613718412, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI5031947, Length=277, Percent_Identity=35.3790613718412, Blast_Score=138, Evalue=7e-33,
Organism=Homo sapiens, GI297632348, Length=273, Percent_Identity=35.1648351648352, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI9910460, Length=260, Percent_Identity=26.1538461538462, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI297632346, Length=200, Percent_Identity=33, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17556280, Length=275, Percent_Identity=30.5454545454545, Blast_Score=118, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6322335, Length=297, Percent_Identity=29.96632996633, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323383, Length=265, Percent_Identity=26.7924528301887, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355835, Length=166, Percent_Identity=31.9277108433735, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17933642, Length=264, Percent_Identity=28.030303030303, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31034; Mature: 31034

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICITDEFNAVYSSLASLINQAGGIMLVAAGQFAVSPVWERNAETCVSLMEQAAESDVSL
CEEEECHHHHHHHHHHHHHHHCCCEEEEECCCEEECCHHHCCHHHHHHHHHHHHHCCCEE
LVLPEALLARDDLDPDLAVKSAQPVEGDFLARLLRESKRNTMTTVLAIHVPSVPGRAFNM
EEECHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHH
LVALQRGKIIARYAKLHLYDAFAIQESRNVDAGKSLPPLLDVDGMKVGLMTCYDLRFPEL
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
ALAHALQGAEILVLPAAWVRGALKEHHWSTLLAARALDTTCYMVAAGECGTRNIGQSRII
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHCC
DPFGVTLAAAAEIPALIIADISAERVRQVRAQLPVLANRRFAPPQLL
CCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCC
>Mature Secondary Structure
MICITDEFNAVYSSLASLINQAGGIMLVAAGQFAVSPVWERNAETCVSLMEQAAESDVSL
CEEEECHHHHHHHHHHHHHHHCCCEEEEECCCEEECCHHHCCHHHHHHHHHHHHHCCCEE
LVLPEALLARDDLDPDLAVKSAQPVEGDFLARLLRESKRNTMTTVLAIHVPSVPGRAFNM
EEECHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCHHHHH
LVALQRGKIIARYAKLHLYDAFAIQESRNVDAGKSLPPLLDVDGMKVGLMTCYDLRFPEL
HHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
ALAHALQGAEILVLPAAWVRGALKEHHWSTLLAARALDTTCYMVAAGECGTRNIGQSRII
HHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHCC
DPFGVTLAAAAEIPALIIADISAERVRQVRAQLPVLANRRFAPPQLL
CCCCHHHHHHHHCCEEEEECCCHHHHHHHHHHCCHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]