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The map label for this gene is speF [H]

Identifier: 218549741

GI number: 218549741

Start: 2480334

End: 2482532

Strand: Direct

Name: speF [H]

Synonym: EFER_2418

Alternate gene names: 218549741

Gene position: 2480334-2482532 (Clockwise)

Preceding gene: 218549739

Following gene: 218549742

Centisome position: 54.05

GC content: 48.84

Gene sequence:

>2199_bases
ATGTCAGAATTAAAAATTGCCGTTAGTCGTTCTTGCCCGGATTGTTTTTCTACTCATCGTGCATGCGTGAATATTGACGA
AAGTAATTATATTGACGTTGCCGCCATTATTTTATCGGTCAATGATGTTGAACGTGGAAAACTCGATGAAATAGACGCTA
CTGGCTATGGCATTCCTGTTTTTATTGCAACGGAAAATGAAGAACGTGTACCAGCAGAATATCTGCCACGTATTTCTGGT
GTCTTCGAGCATTGCGAATCACGTAAAGAGTTTTATGGACGTCAGTTAGAAACCGCTGCCAGCCATTATGAAACGCAACT
GCGCCCGCCCTTCTTCCGCGCACTGGTCGATTATGTCAATCAGGGCAATAGCGCTTTTGACTGCCCGGGTCATCAGGGGG
GTGAGTTTTTCCGTCGTCATCCGGCTGGGAATCAGTTCGTGGAATATTTTGGCGAAATGCTCTTCCGCTCCGACTTGTGT
AATGCCGACGTAGCAATGGGTGATCTTCTGATTCATGAAGGCGCGCCATGCATTGCACAGCAACATGCGGCAAAAGTGTT
TAATGCCGATAAAACGTACTTTGTTTTAAACGGCACATCCTCCTCCAACAAAGTGGTTTTAAACGCCCTGCTGACACCGG
GTGATCTGGTGCTGTTTGACCGTAATAACCATAAGTCTAACCACCACGGAGCGTTGCTACAGGCTGGTGCAACACCGGTT
TATCTGGAAACGGCACGTAACCCGTATGGCTTTATCGGTGGCATTGATGCGCACTGCTTCGAAGAAAGTTATCTGCGTGA
ACTGATTACAGAAGTTGCACCGCAACGGGCAAAAGAAGCGCGTCCGTTCCGCCTCGCTGTAATTCAGTTAGGCACCTACG
ACGGTACTATTTATAACGCCCGCCAGGTGGTGGATAAAATCGGTCATCTGTGTGACTACATCCTGTTTGACTCAGCATGG
GTCGGCTATGAACAGTTTATTCCGATGATGGCGGACTGTTCGCCACTGCTGCTGGATCTTAATGAGAACGATCCGGGTAT
TCTGGTTACGCAATCTGTGCATAAACAGCAGGCTGGTTTTTCCCAGACTTCACAAATTCATAAAAAAGACAGCCATATCA
AAGGGCAACAGCGTTATGTACCGCACAAACGCATGAACAACGCCTTTATGATGCACGCCTCCACCAGCCCGTTCTATCCG
CTGTTTGCCGCACTGGATATCAACGCCAAAATGCATGAAGGTGTCAGCGGTCGTAATATGTGGATGGATTGTGTGGTTAA
CGGTATTAATACCCGCAAATTGATCCTCGATAACTGTCAGCACATTCGTCCGTTCGTTCCTGAACTGGTGGATGGTAAGC
CCTGGCAGTCATATGAAACAGCGCAAATAGCGGTTGATCTGCGCTTCTTTAAATTTGTACCCGGTGAGCACTGGCATTCT
TTTGAAGGCTACGCAGAGAATCAATACTTTGTCGATCCGTGCAAACTGTTGCTGACAACCCCAGGTATTGATGCACGTAA
CGGCGAATACGAAGCGTTCGGTGTACCCGCGACGATTCTTGCTAACTTCCTGCGCGAAAATGGCGTAGTGCCGGAAAAAT
GCGATCTTAACTCCATCCTCTTCCTGCTGACTCCGGCAGAAGATATGGCCAAACTTCAGCAACTTGTTGCCCTGCTGGTT
CGCTTCGAAAAACTACTGGAAGCTGATGCGCCTCTGGCGGAAGTACTGCCTTCCATCTACAAACAGCATGAAGAGCGTTA
CGCCGGTTATACCCTGCGTCAGTTGTGCCAGGAAATGCATGATTTGTATGCCCGTCACAACGTGAAACAACTGCAAAAAG
AGATGTTCCGTAAGGAGCACTTCCCACGCGTCAGCATGAATCCACAAGAAGCCAACTACGCCTATTTACGCGGTGAAGTG
GAGCTGGTTCGTCTGCCGGATGCAGAAGGCCGTATCGCTGCCGAAGGTGCGCTTCCTTATCCTCCGGGTGTGCTGTGTGT
TGTTCCGGGTGAAATCTGGGGTGGTGCTGTTCTGCGTTACTTCAGCGCTCTGGAAGAAGGGATCAACCTGCTGCCAGGTT
TTGCACCGGAGCTGCAGGGTGTCTATATCGAAGAACATGATGGTCGTAAGCAAGTTTGGTGCTATGTCATCAAGCCTCGT
GATGCGCAAAGCACCCTGTTGAAAGGGGAAAAATTATGA

Upstream 100 bases:

>100_bases
TATTTATCAGCGGTGGAGTTTTGCTTTTTTTCCGGCGTGATCGATTTCTCCTTTGAGAAATTGAGGACCTGTTATTACCT
GAAATAAAGAGATGAACAAA

Downstream 100 bases:

>100_bases
GTCAGGCTAAATCGAACAAAATGGGCGTCGTTCAGTTAACCATACTGACGATGGTCAACATGATGGGCTCCGGCATCATC
ATGCTGCCGACAAAGCTTGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVNDVERGKLDEIDATGYGIPVFIATENEERVPAEYLPRISG
VFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYP
LFAALDINAKMHEGVSGRNMWMDCVVNGINTRKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLV
RFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEV
ELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQSTLLKGEKL

Sequences:

>Translated_732_residues
MSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVNDVERGKLDEIDATGYGIPVFIATENEERVPAEYLPRISG
VFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAW
VGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYP
LFAALDINAKMHEGVSGRNMWMDCVVNGINTRKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLV
RFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEV
ELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
DAQSTLLKGEKL
>Mature_731_residues
SELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVNDVERGKLDEIDATGYGIPVFIATENEERVPAEYLPRISGV
FEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCN
ADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPVY
LETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWV
GYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPL
FAALDINAKMHEGVSGRNMWMDCVVNGINTRKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHSF
EGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVR
FEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVE
LVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRD
AQSTLLKGEKL

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=732, Percent_Identity=96.7213114754098, Blast_Score=1483, Evalue=0.0,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=67.0375521557719, Blast_Score=1017, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=678, Percent_Identity=31.858407079646, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1790573, Length=636, Percent_Identity=33.4905660377358, Blast_Score=314, Evalue=1e-86,
Organism=Escherichia coli, GI1786384, Length=659, Percent_Identity=32.1699544764795, Blast_Score=302, Evalue=4e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 82539; Mature: 82408

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVNDVERGKLDEIDATGYGIPV
CCCCEEEECCCCCHHHHCCCEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEE
FIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNA
EEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALDINAKMHEGVSGRNM
HHHHHHHHHHHCCCCCHHCCCHHHCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCCCH
WMDCVVNGINTRKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCC
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEEECCHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLVRFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEECCC
DAQSTLLKGEKL
CHHHHHHCCCCC
>Mature Secondary Structure 
SELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVNDVERGKLDEIDATGYGIPV
CCCEEEECCCCCHHHHCCCEEEECCCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCEEE
FIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASHYETQLRPPFFRALVDYVN
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLCNADVAMGDLLIHEGAPCIAQ
CCCCEECCCCCCCCHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHEECCCCHHHH
QHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVLFDRNNHKSNHHGALLQAGATPV
HHHHHHHCCCCEEEEEECCCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPYGFIGGIDAHCFEESYLRELITEVAPQRAKEARPFRLAVIQLGTYDGTIYNA
EEEECCCCCCEECCCHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEEEEEEECCCCCCHHH
RQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLDLNENDPGILVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMHASTSPFYPLFAALDINAKMHEGVSGRNM
HHHHHHHHHHHCCCCCHHCCCHHHCCCEEEEEECCCCCCEEEEEEECCCHHHCCCCCCCH
WMDCVVNGINTRKLILDNCQHIRPFVPELVDGKPWQSYETAQIAVDLRFFKFVPGEHWHS
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEEECCCCCCCCC
FEGYAENQYFVDPCKLLLTTPGIDARNGEYEAFGVPATILANFLRENGVVPEKCDLNSIL
CCCCCCCCEEECCHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAEDMAKLQQLVALLVRFEKLLEADAPLAEVLPSIYKQHEERYAGYTLRQLCQEMH
EEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
DLYARHNVKQLQKEMFRKEHFPRVSMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPY
HHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEIWGGAVLRYFSALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPR
CCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEEECCC
DAQSTLLKGEKL
CHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]