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The map label for this gene is kdpE [H]

Identifier: 218549739

GI number: 218549739

Start: 2478967

End: 2479644

Strand: Direct

Name: kdpE [H]

Synonym: EFER_2416

Alternate gene names: 218549739

Gene position: 2478967-2479644 (Clockwise)

Preceding gene: 218549738

Following gene: 218549741

Centisome position: 54.02

GC content: 57.08

Gene sequence:

>678_bases
GTGACAAACGTTCTGATTGTTGAAGATGAACAGGCTATTCGTCGCTTTCTGCGCACGGCGCTGGAGGGTGACGGTATGCG
CGTCTTTGAGGCCGAAACGCTGCAACGCGGCTTGCTGGAAGCGGCAACCCGTAAGCCCGATTTGATTATTCTCGATCTCG
GCCTGCCAGACGGTGATGGGATTGAGTTTATCCGCGACCTGCGCCAGTGGAGCGCGGTGCCGGTGATTGTGCTTTCCGCA
CGTAGCGAAGAGAGCGACAAAATCGCCGCGCTGGATGCTGGAGCGGATGATTACCTGAGTAAGCCGTTTGGCATTGGTGA
ATTGCAGGCCCGTCTGCGCGTCGCATTACGCCGCCACTCCGCCACCACCGCGCCCGAGCCGCTGGTGAAATTTTCCGATG
TTACCGTCGATTTAGCTGCCCGCGTGATTCACCGCAGCGAGGAAGAGGTGCATCTCACCCCGATTGAGTTCCGCCTGCTG
GCGGTGCTGCTCAACAATGCCGGAAAAGTGCTCACCCAGCGCCAGCTTCTCAACCAGGTGTGGGGACCAAACGCGGTCGA
ACACAGCCACTATTTGCGTATTTATATGGGACATCTGCGACAAAAACTGGAGCAAGATCCCGCCCGCCCCCGCCATTTCA
TTACTGAAACCGGTATTGGCTATCGTTTTATGCCATGA

Upstream 100 bases:

>100_bases
GCACCATTACCGCGTTCAACCGACCGGAAGGTGGTGCCTGTTTTCGTGTTACACTTCCCCAGCAAACTGCCCCTGAACTT
GAAGAATTTCATGAGGATAT

Downstream 100 bases:

>100_bases
ATGTTTATTCAATAAATGCGCTTAAAAAATTATTAATTTATTATTAATTCTGCCAAAAATATTATTATTTGGCAGTTTTA
ATTTCTTAATGCAAATATAA

Product: DNA-binding transcriptional activator KdpE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPEPLVKFSDVTVDLAARVIHRSEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFMP

Sequences:

>Translated_225_residues
MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSA
RSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPEPLVKFSDVTVDLAARVIHRSEEEVHLTPIEFRLL
AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFMP
>Mature_224_residues
TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSAR
SEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHSATTAPEPLVKFSDVTVDLAARVIHRSEEEVHLTPIEFRLLA
VLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFMP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=99.1071428571429, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=36.7713004484305, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=35.1351351351351, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=36.7713004484305, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=34.051724137931, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.5855855855856, Blast_Score=120, Evalue=9e-29,
Organism=Escherichia coli, GI87082012, Length=222, Percent_Identity=31.981981981982, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=32.2727272727273, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=32.3144104803493, Blast_Score=108, Evalue=2e-25,
Organism=Escherichia coli, GI1789402, Length=220, Percent_Identity=34.0909090909091, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1787229, Length=227, Percent_Identity=29.5154185022026, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=30.7017543859649, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI145693140, Length=238, Percent_Identity=28.1512605042017, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1788550, Length=121, Percent_Identity=33.8842975206612, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI1790299, Length=136, Percent_Identity=30.8823529411765, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1790437, Length=131, Percent_Identity=30.5343511450382, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25391; Mature: 25259

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ATTAPEPLVKFSDVTVDLAARVIHRSEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC
>Mature Secondary Structure 
TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDG
CCEEEECCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCCCCH
IEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS
HHHHHHHHHCCCCCEEEEECCCCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHHHHHHC
ATTAPEPLVKFSDVTVDLAARVIHRSEEEVHLTPIEFRLLAVLLNNAGKVLTQRQLLNQV
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHHHCCHHHHHHHHHHHHH
WGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETGIGYRFMP
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]