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The map label for this gene is bioC [H]

Identifier: 218549659

GI number: 218549659

Start: 2392323

End: 2393078

Strand: Reverse

Name: bioC [H]

Synonym: EFER_2335

Alternate gene names: 218549659

Gene position: 2393078-2392323 (Counterclockwise)

Preceding gene: 218549661

Following gene: 218549658

Centisome position: 52.15

GC content: 56.22

Gene sequence:

>756_bases
ATGGCAACGGTTAATAAACAAGCCATTGCCGCGGCATTTGGTCGGGCAGCCGCACACTATGAGCAACACGCAGATCTACA
GCGTCAGAGTGCTGACGCCTTACTGGCAATGCTCCCACAGCGTACATTCACCCACGTGCTGGACGCGGGTTGTGGACCAG
GCTGGATGAGCCGCCACTGGCGTGAACGTCACGCGCGGGTGACGGCGTTAGATCTTTCGCCACTTATGCTTGAGCAGGCA
CGCCAGAAGGATGCCGCAGACCATTATCTGGCGGGAGATATCGAATCCCTGCCGTTAGCGACTGCGATGTTCGATCTCAC
ATGGAGCAATCTCGCGGTGCAGTGGTGCGGTAATTTATCCACGGCACTCCACGAGCTGTATCGGGTGGTGCGCCCCGGAG
GCATGGTCGCGTTTACCACGCTGGCGCAGGGATCGATACCCGAACTGCATCTGGCGTGGCAGGCGGTGGACGAGCGCCCG
CATGCTAATCGCTTTTTACCGCCAGATGAAATCGAACAGTCGCTGAACGGCGTTAATTATCAACACCATATTCTGCCCAT
CACGCTTTGGTTTGATGATGCGCTCAGTGCCATGCGTTCGCTGAAAGGCATCGGTGCAACGCATCTTCATGAAGGGCGTG
ACCAGCGAATATTAACGCGTTCGCAGTTGCAGCGATTGCAACTGGCCTGGCCGCAACAACAGGGGCGATATCCTCTGACG
TATCATCTTTTTTTGGGAGTGATTGCTCGTGAGTAA

Upstream 100 bases:

>100_bases
ATTCGCCCACCAACCGTACCCGCAGGCACTGCGCGATTGCGCCTGACCTTAACCGCCGCACATGAAACGCAGGATATCGA
CCTGCTGCTGGAGGTGCTGC

Downstream 100 bases:

>100_bases
ACGTTATTTTGTCACCGGAACGGACACCGAAGTGGGGAAAACCGTCGCCAGTGGTGCCCTGTTACAGGCCGCAAAAGCCG
CAGGCTACCGGACGGCAGGG

Product: biotin biosynthesis protein BioC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 250

Protein sequence:

>251_residues
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRTFTHVLDAGCGPGWMSRHWRERHARVTALDLSPLMLEQA
RQKDAADHYLAGDIESLPLATAMFDLTWSNLAVQWCGNLSTALHELYRVVRPGGMVAFTTLAQGSIPELHLAWQAVDERP
HANRFLPPDEIEQSLNGVNYQHHILPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLT
YHLFLGVIARE

Sequences:

>Translated_251_residues
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRTFTHVLDAGCGPGWMSRHWRERHARVTALDLSPLMLEQA
RQKDAADHYLAGDIESLPLATAMFDLTWSNLAVQWCGNLSTALHELYRVVRPGGMVAFTTLAQGSIPELHLAWQAVDERP
HANRFLPPDEIEQSLNGVNYQHHILPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLT
YHLFLGVIARE
>Mature_250_residues
ATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRTFTHVLDAGCGPGWMSRHWRERHARVTALDLSPLMLEQAR
QKDAADHYLAGDIESLPLATAMFDLTWSNLAVQWCGNLSTALHELYRVVRPGGMVAFTTLAQGSIPELHLAWQAVDERPH
ANRFLPPDEIEQSLNGVNYQHHILPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLTY
HLFLGVIARE

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=251, Percent_Identity=93.6254980079681, Blast_Score=457, Evalue=1e-130,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28260; Mature: 28128

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRTFTHVLDAGCGPGWMSRHW
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RERHARVTALDLSPLMLEQARQKDAADHYLAGDIESLPLATAMFDLTWSNLAVQWCGNLS
HHHHCEEEEECCCHHHHHHHHHHHHCCHHHCCCCHHCHHHHHHHHHHHHHHHHHHHCCHH
TALHELYRVVRPGGMVAFTTLAQGSIPELHLAWQAVDERPHANRFLPPDEIEQSLNGVNY
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
QHHILPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLT
EEEEEEEEEEHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCH
YHLFLGVIARE
HHHHHHHHHCC
>Mature Secondary Structure 
ATVNKQAIAAAFGRAAAHYEQHADLQRQSADALLAMLPQRTFTHVLDAGCGPGWMSRHW
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
RERHARVTALDLSPLMLEQARQKDAADHYLAGDIESLPLATAMFDLTWSNLAVQWCGNLS
HHHHCEEEEECCCHHHHHHHHHHHHCCHHHCCCCHHCHHHHHHHHHHHHHHHHHHHCCHH
TALHELYRVVRPGGMVAFTTLAQGSIPELHLAWQAVDERPHANRFLPPDEIEQSLNGVNY
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCC
QHHILPITLWFDDALSAMRSLKGIGATHLHEGRDQRILTRSQLQRLQLAWPQQQGRYPLT
EEEEEEEEEEHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCH
YHLFLGVIARE
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3058702; 9278503 [H]