Click here to switch to the map view.

The map label for this gene is ccmF [H]

Identifier: 218549611

GI number: 218549611

Start: 2345204

End: 2347147

Strand: Reverse

Name: ccmF [H]

Synonym: EFER_2286

Alternate gene names: 218549611

Gene position: 2347147-2345204 (Counterclockwise)

Preceding gene: 218549612

Following gene: 218549610

Centisome position: 51.15

GC content: 56.53

Gene sequence:

>1944_bases
ATGATGCCAGAAATTGGTAACGGACTGCTGTGCCTGGCGCTAGGAATTGCGCTGTTGCTGTCCGTGTATCCGCTATGGGG
CGTGGCGCGCGGGGATGCGCGCATGATGGCTTCTTCGCGCTTGTTTGCCTGGCTGCTATTTATGTCTGTGGCTGGCGCAT
TTCTGGTGCTGGTCAATGCTTTCGTGGTGAATGACTTTACTGTCACCTATGTTGCCAGCAACTCCAATACCCAGCTTCCG
GTGTGGTATCGCGTGGCGGCAACCTGGGGTGCGCATGAAGGCTCGCTACTGCTGTGGGTGCTGCTGATGAGCGGCTGGAC
ATTTGCGGTGGCGATTTTTAGTCAGCGTATTCCGCTGGATATTGTGGCCCGTGTACTGGCGATAATGGGGATGGTCTGTG
TCGGCTTTTTGCTGTTCATTCTCTTTACCTCTAACCCGTTCTCACGCACGCTGCCGAATTTCCCGATTGAAGGTCGCGAT
CTTAACCCGCTGTTGCAGGATCCGGGGCTGATCTTCCACCCGCCCCTGCTCTATATGGGGTACGTCGGTTTCTCGGTGGC
GTTTGCTTTCGCCATTGCTTCTTTGTTGAGTGGGCGTCTGGACAGCACCTATGCGCGTTTTACCCGCCCGTGGACGCTGG
CAGCGTGGATCTTCCTGACGCTCGGCATTGTGCTCGGTTCCGCATGGGCCTATTACGAACTCGGCTGGGGCGGCTGGTGG
TTCTGGGATCCGGTAGAAAACGCCTCGTTTATGCCGTGGCTGGTGGGGACTGCGCTGATGCACTCACTGGCGGTCACTGA
ACAACGCGCCAGCTTCAAAGCGTGGACATTACTGCTGGCAATCAGTGCCTTCTCGTTGTGTCTGTTGGGGACTTTCCTCG
TGCGTTCCGGCGTGCTGGTATCGGTACACGCGTTTGCGTCTGATCCGGCGCGCGGTATGTTTATCCTCGCCTTTATGGTG
CTGGTGATTGGCGGTTCGCTGCTGCTGTTTGCCGCGCGTGGACACAAAGTTCGCTCACGCGTAAACAATGCGCTGTGGTC
GCGGGAATCTTTGCTGTTAGCGAACAACGTTTTGCTGGTCGCCGCGATGCTGGTGGTGTTGCTGGGGACGCTGCTGCCGC
TGGTGCACAAGCAACTGGGACTGGGCAGCATTTCGATTGGCGAACCGTTCTTCAACACTATGTTTACCTGGCTGATGGTG
CCGTTTGCGCTACTGCTTGGTGTCGGTCCACTGGTGCGCTGGGGGCGCGATCGCCCACGTAAAATCCGCAATTTATTGAT
TATCGCTTTCATCTCTACGCTGGTGTTGTCGCTGATAGTGCCGTGGCTGTTCGAAAGCAAAGTTGTGGCGATGACGGTGC
TCGGCCTGGCAATGGCCTGCTGGATTGCGGTGCTGGCAATTGCGGAAGCTGCGCTGCGTATTTCACGCGGCACGAAAACC
ACCTTCAGTTATTGGGGAATGGTGGCGGCTCATCTGGGGCTGGCAGTGACAATTGTTGGTATTGCCTTTAGCCAGAACTA
TAGCGTTGAGCGTGATGTGCGCATGAAGTCCGGCGATAGCGTCGATATTCATGAATATCGCTTCACCTTCCGTGATGTCA
AAGAAGTGACTGGTCCGAACTGGCGCGGCGGTGTGGCGACTATCGGCGTAACGCGAGATGGCAAGCCGGAAACGGTGCTG
TATGCGGAAAAACGTTATTACAACACAGCCGGGTCGATGATGACAGAAGCAGCGATTGATGGTGGGATCACGCGTGACCT
GTACGCAGCGCTCGGTGAAGAGTTGGAAAACGGTGCGTGGGCTGTGCGCCTTTACTACAAACCGTTTGTTCGCTGGATCT
GGGCGGGCGGGCTGATGATGGCGTTGGGCGGACTGCTGTGTCTGTTTGATCCTCGCTATCGTAAGCGCGTGAACCCGCAA
AAAACTGCGCCGGAGGCTGTATGA

Upstream 100 bases:

>100_bases
TACTGGCGAAACACGATGAAAACTACACGCCGCCAGAAGTCGAGAAAGCGATGGAAGCTAATCACCGTCGCCCGGCGAGT
GTTTATAAGGACCCAGCATC

Downstream 100 bases:

>100_bases
AGCGCAAAGTATTGTTAATTCCTTTAATTATCTTCCTGGCGATTGCTGCGGCGTTGCTGTGGCAGCTGGCGCGTAATGCC
GAAGGGGATGATCCGACCAA

Product: heme lyase, CcmF subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 647; Mature: 647

Protein sequence:

>647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVCVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLIVPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV

Sequences:

>Translated_647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVCVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLIVPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV
>Mature_647_residues
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLP
VWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLDIVARVLAIMGMVCVGFLLFILFTSNPFSRTLPNFPIEGRD
LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMV
LVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMV
PFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLIVPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVL
YAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQ
KTAPEAV

Specific function: Required for the biogenesis of c-type cytochromes. Possible subunit of a heme lyase [H]

COG id: COG1138

COG function: function code O; Cytochrome c biogenesis factor

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ccmF/cycK/ccl1/nrfE/ccsA family [H]

Homologues:

Organism=Escherichia coli, GI1788524, Length=647, Percent_Identity=99.3817619783617, Blast_Score=1280, Evalue=0.0,
Organism=Escherichia coli, GI1790511, Length=581, Percent_Identity=38.382099827883, Blast_Score=315, Evalue=6e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003567
- InterPro:   IPR003568 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 71419; Mature: 71419

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVCVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLIVPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAV
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAWLLFMSVAGAFLVLVNA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLLMSGWTFAVAIFSQRIPLD
HHHCCEEEEEEECCCCCCCEEEEEEEECCCCCCCHHHHHHHHHCCHHHHHHHHHCCCCHH
IVARVLAIMGMVCVGFLLFILFTSNPFSRTLPNFPIEGRDLNPLLQDPGLIFHPPLLYMG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCHHHHCCCCEECCHHHHHH
YVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIFLTLGIVLGSAWAYYELGWGGWW
HHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHEEEECCCCEE
FWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWTLLLAISAFSLCLLGTFLVRSGVLV
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
SVHAFASDPARGMFILAFMVLVIGGSLLLFAARGHKVRSRVNNALWSRESLLLANNVLLV
EEEECCCCCCCHHHHHHHHHHHHCCHHEEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
AAMLVVLLGTLLPLVHKQLGLGSISIGEPFFNTMFTWLMVPFALLLGVGPLVRWGRDRPR
HHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHH
KIRNLLIIAFISTLVLSLIVPWLFESKVVAMTVLGLAMACWIAVLAIAEAALRISRGTKT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TFSYWGMVAAHLGLAVTIVGIAFSQNYSVERDVRMKSGDSVDIHEYRFTFRDVKEVTGPN
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCCCC
WRGGVATIGVTRDGKPETVLYAEKRYYNTAGSMMTEAAIDGGITRDLYAALGEELENGAW
CCCCEEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCE
AVRLYYKPFVRWIWAGGLMMALGGLLCLFDPRYRKRVNPQKTAPEAV
EEEEHHHHHHHHHHHCCHHHHHCCHHHHCCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 7635817 [H]