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The map label for this gene is narP [H]

Identifier: 218549608

GI number: 218549608

Start: 2342911

End: 2343561

Strand: Direct

Name: narP [H]

Synonym: EFER_2283

Alternate gene names: 218549608

Gene position: 2342911-2343561 (Clockwise)

Preceding gene: 218549607

Following gene: 218549624

Centisome position: 51.06

GC content: 49.16

Gene sequence:

>651_bases
ATGAATATGCCTGAAACAACACCTTTTCAGGTGCTGATCGTGGATGATCATCCACTGATGCGACGAGGAATTCGTCAATT
ACTGGAACTGGACCCGGCATTTGAAGTGGTCGCCGAAGCAGGCGATGGCGCAAGCGCGATCGATCTGGCTAATCGCCTTG
ATCTTGATCTGATCCTGCTGGATCTGAACATGAAGGGTATGAGTGGCCTGGATACCCTCAATGCTCTACGCCGGGATGGC
GTGACGGCACAAATTATCATCATTACTGTTTCTGACTCTGCCAGCGATATCTATGCGTTAATCGATGCGGGTGCAGATGG
CTATCTACTGAAAGACAGTGAGCCGGAAAGTCTGTTGGCCGCGATTCAAAAAGGGGCGAACGGTGGAAAAGTATTCAGCG
CCCGCGTCAGTGAATATCTGCGCGAACGTGAACGCTTTGGTTCAAAAGATGATCCGTTCAGCACTCTTACAGAACGTGAG
CTTGATGTATTACACGAACTGGCGAAAGGTTTATCCAATAAACAGATTGCCTCGGCACTGAATATTTCCGAGCAGACAGT
AAAGGTACATATCCGCAACTTACTGCGTAAACTTAATGTCCGCTCCCGTGTGGCGGCCACCATTCTGTTCCTGCAACATC
GCGGAATATAA

Upstream 100 bases:

>100_bases
CCATAAGGAAAATAGGGTAAAATTCCTGGTCTCGTCAGCATAATTAATCATGCTGATTTTCACGCCATAAACAATAACGA
TTCTAATAATTACTCAGGAG

Downstream 100 bases:

>100_bases
TAAAAAAATAGCCCGATGGATTTCCTATCGGGCTTGTTCTTATTTACTCTCCTGTGGTGATAAGTGTTGCATCGCCTGCG
CGATACTGCGTTCAATCACC

Product: transcriptional regulator NarP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MNMPETTPFQVLIVDDHPLMRRGIRQLLELDPAFEVVAEAGDGASAIDLANRLDLDLILLDLNMKGMSGLDTLNALRRDG
VTAQIIIITVSDSASDIYALIDAGADGYLLKDSEPESLLAAIQKGANGGKVFSARVSEYLRERERFGSKDDPFSTLTERE
LDVLHELAKGLSNKQIASALNISEQTVKVHIRNLLRKLNVRSRVAATILFLQHRGI

Sequences:

>Translated_216_residues
MNMPETTPFQVLIVDDHPLMRRGIRQLLELDPAFEVVAEAGDGASAIDLANRLDLDLILLDLNMKGMSGLDTLNALRRDG
VTAQIIIITVSDSASDIYALIDAGADGYLLKDSEPESLLAAIQKGANGGKVFSARVSEYLRERERFGSKDDPFSTLTERE
LDVLHELAKGLSNKQIASALNISEQTVKVHIRNLLRKLNVRSRVAATILFLQHRGI
>Mature_216_residues
MNMPETTPFQVLIVDDHPLMRRGIRQLLELDPAFEVVAEAGDGASAIDLANRLDLDLILLDLNMKGMSGLDTLNALRRDG
VTAQIIIITVSDSASDIYALIDAGADGYLLKDSEPESLLAAIQKGANGGKVFSARVSEYLRERERFGSKDDPFSTLTERE
LDVLHELAKGLSNKQIASALNISEQTVKVHIRNLLRKLNVRSRVAATILFLQHRGI

Specific function: This protein activates the expression of the nitrate reductase (narGHJI) and formate dehydrogenase-N (fdnGHI) operons and represses the transcription of the fumarate reductase (frdABCD) operon in response to a nitrate/nitrite induction signal transmitted

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=213, Percent_Identity=85.9154929577465, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1787473, Length=214, Percent_Identity=43.4579439252336, Blast_Score=150, Evalue=4e-38,
Organism=Escherichia coli, GI1788222, Length=206, Percent_Identity=31.5533980582524, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790102, Length=194, Percent_Identity=35.5670103092784, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786747, Length=199, Percent_Identity=29.1457286432161, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1788712, Length=191, Percent_Identity=28.7958115183246, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788546, Length=203, Percent_Identity=30.5418719211823, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 23733; Mature: 23733

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMPETTPFQVLIVDDHPLMRRGIRQLLELDPAFEVVAEAGDGASAIDLANRLDLDLILL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCEEEEEE
DLNMKGMSGLDTLNALRRDGVTAQIIIITVSDSASDIYALIDAGADGYLLKDSEPESLLA
ECCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHH
AIQKGANGGKVFSARVSEYLRERERFGSKDDPFSTLTERELDVLHELAKGLSNKQIASAL
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NISEQTVKVHIRNLLRKLNVRSRVAATILFLQHRGI
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNMPETTPFQVLIVDDHPLMRRGIRQLLELDPAFEVVAEAGDGASAIDLANRLDLDLILL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCEEEEEE
DLNMKGMSGLDTLNALRRDGVTAQIIIITVSDSASDIYALIDAGADGYLLKDSEPESLLA
ECCCCCCCCHHHHHHHHHCCCEEEEEEEEECCCCCCEEEEEECCCCCEEECCCCHHHHHH
AIQKGANGGKVFSARVSEYLRERERFGSKDDPFSTLTERELDVLHELAKGLSNKQIASAL
HHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NISEQTVKVHIRNLLRKLNVRSRVAATILFLQHRGI
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501030; 9278503 [H]