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The map label for this gene is rtn [H]

Identifier: 218549592

GI number: 218549592

Start: 2324646

End: 2326202

Strand: Direct

Name: rtn [H]

Synonym: EFER_2266

Alternate gene names: 218549592

Gene position: 2324646-2326202 (Clockwise)

Preceding gene: 218549591

Following gene: 218549593

Centisome position: 50.66

GC content: 48.94

Gene sequence:

>1557_bases
ATGTTTACAGCTGCCAACGCATCAGGTCGAAAAATCCTTCTTACCTGTTTCATTACAGGCCTGGTCGTTGCTGTTATCAT
CAGTTGCTTACAGTTTACAGTGAGCTGGCATAAACGTGAGGTGAAGTACGATACGCTGATCACTGATATCAAAACTTACC
TGGTCCACTATTTTGCCGATCTGAAAACCTCTACCGACAAGCTGCAGCCATTGACGTTATCGTCCTGTAAAAAAGCAGCC
CCTGAACTTACTGCCAAAGCTGCGTTCAGTCTTAATGTTCGGACCTTTTTGTTAGTCAGAGATAAAAAAGCATTTTGCTC
GTCGGCAACAGGCAATATGGATATCCCCCTCGCCCACCTTGTTCCGGCACTGGATATTTCTAAAGATGTTGATATCGCCA
TCTTGCCCGGAACCCCCATGATGCCCGGGAAACCCGCCATGGTGATCTGGTATCGCAATCCGCTTATCAGCAACAGCGGT
GTCTTCACTGCACTCAATCTTAATTTGACGCCTTATCTTCTTTATACCTCACGACAGGAAGATTTTGACGGGATTGCCAT
GATTGTTGGCGATACGGTGCTCTCAACATCTTCTTCTCACTTGCTCAATATCAATGAGCTAAGCGGTCCGCCAGCACGCC
AGGTGAAAGTGGAAGGTATACCGCTGACAGTGCGCCTTTATGCTACTGAATGGACATGGAATGATTTGTGGTACGCCCTA
CTCCTTGGCGGTATGAGTGGTATCGCAGCGGGTCTGCTCTGTTTTTATATTCTGTCTGTTCGTCTGCGTCCCGGTAGAGA
AATACTTACCGCGATTAAACGCGACCAGTTCTATGTGGTCTATCAACCGGCGGTAGATACACAAAGCCTGAAGGTAACCG
GGCTGGAAGTACTCCTGCGCTGGCGTCATCCTGTAGCGGGCGAGATCCCACCGGATGCCTTTATTCACTATGCCGAAGCC
CAGCGGATGATCGTACCGCTGACGCAACATCTCTTTGAACTTATTCGCCGTGATGCCCACGTACTGCAACGGGTACTGCC
AGTTGGCGTGAAGTTCGGCATTAACATTGCGCCTGACCATCTGCATGGTGAAACGTTCAAAAAGGATATCCGCCAGTTAG
TCGAATCCTTACCGGCGCATCATTTCCAGATCGTTCTGGAGATTACCGAGCGTGATATGCTGAAGCAACACGAAGCTACG
CAACTCTTTGAGTGGTTGCATTCCGTCGGTGTTGAAATCGCCATTGACGATTTTGGTACCGGGCACAGTGCATTGATTTA
TCTCGAACGCTTCACCCTTGATTACCTGAAGATTGATCGTGGCTTTATTAATGCGATTGGTACGGAAACGGTCACCTCAC
CAGTGCTTGACGCCGTACTCACTTTATCAAAACGCCTTAATATGCTGACCGTAGCCGAAGGTGTAGAAACGCCAGAGCAA
GCCAAATGGCTGCGTGATCGTGGCGTTAATTTCCTTCAGGGCTACTGGATCAGCCGTCCCTTGCCACTGAATGAGTTTGT
GCAATGGCTGAAGAAACCAGACACACCGCAGTGGTAA

Upstream 100 bases:

>100_bases
TCGGCATAAGAAATGTATGACGATACAGCAAAATCCAGGCTATAGTCCTGCCTGACACCCCCTTTACTTACTGTAATTCT
GCAGGATATCTTCAGTAACT

Downstream 100 bases:

>100_bases
GCCAGACAGGCGTCCATTATGATTAAAATATGACGCTTGCCGCTTGCGGAACAAATTATTAAGGAAAATCCCTTGCAGAT
GATTGCTCACCTGACGCTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MFTAANASGRKILLTCFITGLVVAVIISCLQFTVSWHKREVKYDTLITDIKTYLVHYFADLKTSTDKLQPLTLSSCKKAA
PELTAKAAFSLNVRTFLLVRDKKAFCSSATGNMDIPLAHLVPALDISKDVDIAILPGTPMMPGKPAMVIWYRNPLISNSG
VFTALNLNLTPYLLYTSRQEDFDGIAMIVGDTVLSTSSSHLLNINELSGPPARQVKVEGIPLTVRLYATEWTWNDLWYAL
LLGGMSGIAAGLLCFYILSVRLRPGREILTAIKRDQFYVVYQPAVDTQSLKVTGLEVLLRWRHPVAGEIPPDAFIHYAEA
QRMIVPLTQHLFELIRRDAHVLQRVLPVGVKFGINIAPDHLHGETFKKDIRQLVESLPAHHFQIVLEITERDMLKQHEAT
QLFEWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLSKRLNMLTVAEGVETPEQ
AKWLRDRGVNFLQGYWISRPLPLNEFVQWLKKPDTPQW

Sequences:

>Translated_518_residues
MFTAANASGRKILLTCFITGLVVAVIISCLQFTVSWHKREVKYDTLITDIKTYLVHYFADLKTSTDKLQPLTLSSCKKAA
PELTAKAAFSLNVRTFLLVRDKKAFCSSATGNMDIPLAHLVPALDISKDVDIAILPGTPMMPGKPAMVIWYRNPLISNSG
VFTALNLNLTPYLLYTSRQEDFDGIAMIVGDTVLSTSSSHLLNINELSGPPARQVKVEGIPLTVRLYATEWTWNDLWYAL
LLGGMSGIAAGLLCFYILSVRLRPGREILTAIKRDQFYVVYQPAVDTQSLKVTGLEVLLRWRHPVAGEIPPDAFIHYAEA
QRMIVPLTQHLFELIRRDAHVLQRVLPVGVKFGINIAPDHLHGETFKKDIRQLVESLPAHHFQIVLEITERDMLKQHEAT
QLFEWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLSKRLNMLTVAEGVETPEQ
AKWLRDRGVNFLQGYWISRPLPLNEFVQWLKKPDTPQW
>Mature_518_residues
MFTAANASGRKILLTCFITGLVVAVIISCLQFTVSWHKREVKYDTLITDIKTYLVHYFADLKTSTDKLQPLTLSSCKKAA
PELTAKAAFSLNVRTFLLVRDKKAFCSSATGNMDIPLAHLVPALDISKDVDIAILPGTPMMPGKPAMVIWYRNPLISNSG
VFTALNLNLTPYLLYTSRQEDFDGIAMIVGDTVLSTSSSHLLNINELSGPPARQVKVEGIPLTVRLYATEWTWNDLWYAL
LLGGMSGIAAGLLCFYILSVRLRPGREILTAIKRDQFYVVYQPAVDTQSLKVTGLEVLLRWRHPVAGEIPPDAFIHYAEA
QRMIVPLTQHLFELIRRDAHVLQRVLPVGVKFGINIAPDHLHGETFKKDIRQLVESLPAHHFQIVLEITERDMLKQHEAT
QLFEWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLSKRLNMLTVAEGVETPEQ
AKWLRDRGVNFLQGYWISRPLPLNEFVQWLKKPDTPQW

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=518, Percent_Identity=77.6061776061776, Blast_Score=877, Evalue=0.0,
Organism=Escherichia coli, GI87081980, Length=513, Percent_Identity=31.3840155945419, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI87081845, Length=530, Percent_Identity=26.9811320754717, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786507, Length=250, Percent_Identity=36.8, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1790496, Length=286, Percent_Identity=31.8181818181818, Blast_Score=148, Evalue=9e-37,
Organism=Escherichia coli, GI1787541, Length=244, Percent_Identity=31.9672131147541, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI87081743, Length=357, Percent_Identity=29.9719887955182, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081921, Length=261, Percent_Identity=31.4176245210728, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=31.6205533596838, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788849, Length=245, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87082096, Length=248, Percent_Identity=30.6451612903226, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1787055, Length=251, Percent_Identity=30.2788844621514, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787410, Length=113, Percent_Identity=30.9734513274336, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 58256; Mature: 58256

Theoretical pI: Translated: 7.71; Mature: 7.71

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTAANASGRKILLTCFITGLVVAVIISCLQFTVSWHKREVKYDTLITDIKTYLVHYFAD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTSTDKLQPLTLSSCKKAAPELTAKAAFSLNVRTFLLVRDKKAFCSSATGNMDIPLAHL
HCCCCCCCCCCCHHHHHHCCCHHHHHHEEEECEEEEEEEECCHHHHCCCCCCCCCCHHHH
VPALDISKDVDIAILPGTPMMPGKPAMVIWYRNPLISNSGVFTALNLNLTPYLLYTSRQE
HCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCEECCCCEEEEEECCCCEEEEEECCCC
DFDGIAMIVGDTVLSTSSSHLLNINELSGPPARQVKVEGIPLTVRLYATEWTWNDLWYAL
CCCCEEEEECCHHHCCCCCCEEEECCCCCCCCCEEEECCCEEEEEEEEEECCHHHHHHHH
LLGGMSGIAAGLLCFYILSVRLRPGREILTAIKRDQFYVVYQPAVDTQSLKVTGLEVLLR
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCEEEHHHHHHHH
WRHPVAGEIPPDAFIHYAEAQRMIVPLTQHLFELIRRDAHVLQRVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEECCCC
LHGETFKKDIRQLVESLPAHHFQIVLEITERDMLKQHEATQLFEWLHSVGVEIAIDDFGT
CCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLSKRLNMLTVAEGVETPEQ
CCEEEEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHH
AKWLRDRGVNFLQGYWISRPLPLNEFVQWLKKPDTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFTAANASGRKILLTCFITGLVVAVIISCLQFTVSWHKREVKYDTLITDIKTYLVHYFAD
CCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKTSTDKLQPLTLSSCKKAAPELTAKAAFSLNVRTFLLVRDKKAFCSSATGNMDIPLAHL
HCCCCCCCCCCCHHHHHHCCCHHHHHHEEEECEEEEEEEECCHHHHCCCCCCCCCCHHHH
VPALDISKDVDIAILPGTPMMPGKPAMVIWYRNPLISNSGVFTALNLNLTPYLLYTSRQE
HCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCEECCCCEEEEEECCCCEEEEEECCCC
DFDGIAMIVGDTVLSTSSSHLLNINELSGPPARQVKVEGIPLTVRLYATEWTWNDLWYAL
CCCCEEEEECCHHHCCCCCCEEEECCCCCCCCCEEEECCCEEEEEEEEEECCHHHHHHHH
LLGGMSGIAAGLLCFYILSVRLRPGREILTAIKRDQFYVVYQPAVDTQSLKVTGLEVLLR
HHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCEEEHHHHHHHH
WRHPVAGEIPPDAFIHYAEAQRMIVPLTQHLFELIRRDAHVLQRVLPVGVKFGINIAPDH
HCCCCCCCCCHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCEECCCC
LHGETFKKDIRQLVESLPAHHFQIVLEITERDMLKQHEATQLFEWLHSVGVEIAIDDFGT
CCCHHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
GHSALIYLERFTLDYLKIDRGFINAIGTETVTSPVLDAVLTLSKRLNMLTVAEGVETPEQ
CCEEEEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCHHH
AKWLRDRGVNFLQGYWISRPLPLNEFVQWLKKPDTPQW
HHHHHHCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]