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The map label for this gene is wzzB [H]

Identifier: 218549441

GI number: 218549441

Start: 2135141

End: 2136121

Strand: Reverse

Name: wzzB [H]

Synonym: EFER_2110

Alternate gene names: 218549441

Gene position: 2136121-2135141 (Counterclockwise)

Preceding gene: 218549442

Following gene: 218549431

Centisome position: 46.55

GC content: 44.85

Gene sequence:

>981_bases
TTGATTAGAGTGGAAAATAACCATATCTCTGGTCGTAGCAACGACCCAGAACAGATAGATTTGATTGATCTTTTGATGCA
GCTCTGGCGCGGTAAGCTCACTATCATTGCTTGCATAGTTGTTGCTATTGCGCTTGCAGTGGGGTACCTGGTAATTGCTA
AAGAAAAATGGACTTCAACAGCAATAATCACTAAACCTGATGTGGCGCAGATTGGTGCTTATAGCAATGCTCTTGAAGTA
CTCTATGGGGGAGGGGCACCGAAAGTTTCTGATGTCCAATATGATTTTTTTAACCGTTTTAGTACTGCACTTTTTGCATT
AGGGGAGAACTTAGATAACCTAGAGAAACCTGAGAAACTTATCATTGAGCCAACCATAAAAGGGCAAAGCTTACCATTAG
CGGTGTCCTATGTCGGTCAAACCGCAGAGGGAGCGCAACGGCAATTAGCTGAGTATCTTCAGCAGGTTGATGAGCTGGTA
GCCAAAGAGCTGGATGGCGATTTGCAAGATAACATTAAACTGCAAACCACGACTCTTGAAGACTCTTTAAAAACTCAGGA
AATGGTTGCGCAGGAGCAGAAAGATTTGCGTATCAAGCAGATTAAAGAAGCGCTTCGTTATGCGATGCAGGCAAATGTCA
CTAAACCTCAAATCCAGCAAACTCAGGACGTAACCCAGGATTCAATGTTCTTGCTTGGTAGCGATGCCCTCAATGCAATG
GTTGAACACGAAGCTACCCGACCTCTGGTATTTTCTCCTGAATATTATCGGACGCGTCAAACTTTGTTGGATATTGCAGA
TCTGAAAGTCGATAACATTAATGTTCACGCTTATCGCTATGTCATGAAACCGACATTGCCAGTGCGTCGCGATAGCCCGA
AAAAGGCAATCACCTTGATTCTGGCGGTGTTGCTGGGCGGCATGGTTGGCGCGGGGATTGTACTGGGGCGTAACGCTCTA
CGTAATTACAACGCGAAGTAA

Upstream 100 bases:

>100_bases
CGCTTAATTTAAACATCAATCAATTTTATCATTTATCCTATAGCATAAATCATAATTATAGCTAAACTACTGTTGGCTAA
ACCTAATTTTATATAGGGTA

Downstream 100 bases:

>100_bases
TCTTTTCGGTTTTAAAGAAAAAGGGCAGGGTGGTGACACCTTGCCCTTTTTTTGCCGGATGCGACAACAACATCGTATCC
GCTTACCCCGCAATCACTGA

Product: polysaccharide antigen chain regulator

Products: NA

Alternate protein names: Polysaccharide antigen chain regulator [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MIRVENNHISGRSNDPEQIDLIDLLMQLWRGKLTIIACIVVAIALAVGYLVIAKEKWTSTAIITKPDVAQIGAYSNALEV
LYGGGAPKVSDVQYDFFNRFSTALFALGENLDNLEKPEKLIIEPTIKGQSLPLAVSYVGQTAEGAQRQLAEYLQQVDELV
AKELDGDLQDNIKLQTTTLEDSLKTQEMVAQEQKDLRIKQIKEALRYAMQANVTKPQIQQTQDVTQDSMFLLGSDALNAM
VEHEATRPLVFSPEYYRTRQTLLDIADLKVDNINVHAYRYVMKPTLPVRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK

Sequences:

>Translated_326_residues
MIRVENNHISGRSNDPEQIDLIDLLMQLWRGKLTIIACIVVAIALAVGYLVIAKEKWTSTAIITKPDVAQIGAYSNALEV
LYGGGAPKVSDVQYDFFNRFSTALFALGENLDNLEKPEKLIIEPTIKGQSLPLAVSYVGQTAEGAQRQLAEYLQQVDELV
AKELDGDLQDNIKLQTTTLEDSLKTQEMVAQEQKDLRIKQIKEALRYAMQANVTKPQIQQTQDVTQDSMFLLGSDALNAM
VEHEATRPLVFSPEYYRTRQTLLDIADLKVDNINVHAYRYVMKPTLPVRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK
>Mature_326_residues
MIRVENNHISGRSNDPEQIDLIDLLMQLWRGKLTIIACIVVAIALAVGYLVIAKEKWTSTAIITKPDVAQIGAYSNALEV
LYGGGAPKVSDVQYDFFNRFSTALFALGENLDNLEKPEKLIIEPTIKGQSLPLAVSYVGQTAEGAQRQLAEYLQQVDELV
AKELDGDLQDNIKLQTTTLEDSLKTQEMVAQEQKDLRIKQIKEALRYAMQANVTKPQIQQTQDVTQDSMFLLGSDALNAM
VEHEATRPLVFSPEYYRTRQTLLDIADLKVDNINVHAYRYVMKPTLPVRRDSPKKAITLILAVLLGGMVGAGIVLGRNAL
RNYNAK

Specific function: Confers a modal distribution of chain length on the O- antigen component of lipopolysaccharide (LPS). Gives rise to a reduced number of short chain molecules and increases in numbers of longer molecules, with a modal value of 13 (in strain O111/M92) and o

COG id: COG3765

COG function: function code M; Chain length determinant protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the wzzB/cld/rol family [H]

Homologues:

Organism=Escherichia coli, GI87082029, Length=326, Percent_Identity=72.3926380368098, Blast_Score=479, Evalue=1e-137,
Organism=Escherichia coli, GI87082332, Length=332, Percent_Identity=27.1084337349398, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786802, Length=347, Percent_Identity=28.5302593659942, Blast_Score=108, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003856 [H]

Pfam domain/function: PF02706 Wzz [H]

EC number: NA

Molecular weight: Translated: 36285; Mature: 36285

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRVENNHISGRSNDPEQIDLIDLLMQLWRGKLTIIACIVVAIALAVGYLVIAKEKWTST
CEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCE
AIITKPDVAQIGAYSNALEVLYGGGAPKVSDVQYDFFNRFSTALFALGENLDNLEKPEKL
EEEECCCHHHHCCHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IIEPTIKGQSLPLAVSYVGQTAEGAQRQLAEYLQQVDELVAKELDGDLQDNIKLQTTTLE
EEEECCCCCCCCEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
DSLKTQEMVAQEQKDLRIKQIKEALRYAMQANVTKPQIQQTQDVTQDSMFLLGSDALNAM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHEEECHHHHHHH
VEHEATRPLVFSPEYYRTRQTLLDIADLKVDNINVHAYRYVMKPTLPVRRDSPKKAITLI
HHHCCCCCEEECCHHHHHHHHHHHHHHCEECCCEEEEEEEEECCCCCCCCCCHHHHHHHH
LAVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MIRVENNHISGRSNDPEQIDLIDLLMQLWRGKLTIIACIVVAIALAVGYLVIAKEKWTST
CEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEECCCCCE
AIITKPDVAQIGAYSNALEVLYGGGAPKVSDVQYDFFNRFSTALFALGENLDNLEKPEKL
EEEECCCHHHHCCHHHHHHHEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCE
IIEPTIKGQSLPLAVSYVGQTAEGAQRQLAEYLQQVDELVAKELDGDLQDNIKLQTTTLE
EEEECCCCCCCCEEHEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHH
DSLKTQEMVAQEQKDLRIKQIKEALRYAMQANVTKPQIQQTQDVTQDSMFLLGSDALNAM
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHEEECHHHHHHH
VEHEATRPLVFSPEYYRTRQTLLDIADLKVDNINVHAYRYVMKPTLPVRRDSPKKAITLI
HHHCCCCCEEECCHHHHHHHHHHHHHHCEECCCEEEEEEEEECCCCCCCCCCHHHHHHHH
LAVLLGGMVGAGIVLGRNALRNYNAK
HHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]