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The map label for this gene is gapC [H]

Identifier: 218548937

GI number: 218548937

Start: 1624659

End: 1625741

Strand: Direct

Name: gapC [H]

Synonym: EFER_1585

Alternate gene names: 218548937

Gene position: 1624659-1625741 (Clockwise)

Preceding gene: 218548933

Following gene: 218548941

Centisome position: 35.41

GC content: 45.8

Gene sequence:

>1083_bases
TTGTGGCATTGCTCACCCAGCCATCATGGTCTATGCCTGGAAGGGAAAAATCCCCCTTCTCAATCCCGACAGGAGATCAC
CATGAGTAAGATTGGCATTAATGGTTTTGGTCGTATCGGTCGTCTGGTATTGCGTCGTTTACTGGAAGTGAAAAGCGATG
TGGAAGTGGTCGCAATTAACGATCTCACCTCCCCTAAAATTCTCGCGTATCTGTTAAAACATGACTCTAACTATGGTCAG
TTTCCATGGAGTGTTGATTTTACTGAAGATGCGTTAATTGTAGACGGCAAAGAAATTGCTGTTTACGCCGAAAAAGACGC
AAGAAACATTCCCTGGAAAGCGAAAGGCGCAGACATCATCGTTGAATGCACTGGATTTTACACATCTGGCGAAAAATCGC
AGGCGCATCTGGATGCGGGAGCGAAAAAAGTTCTTATTTCCGCGCCCGCTGGTGATATGAAAACCATTGTCTATCATGTC
AATGAAGATACGCTGGCAGCCAGTGATACCATAATTTCTGTTGCCTCATGCACGACCAACTGCCTTGCTCCGATGGCAAA
GGCCCTTCATGACAGCTTTGGTATTAAAGTGGGAACAATGACCACAATTCACGCTTATACCGGTACTCAGTCCTTAGTTG
ATGGGCCACGTGGTAAAGATTTACGTGCATCGAGAGCGGCGGCAGAAAATATCATTCCCCACACCACCGGTGCGGCAAAA
GCGATTGGCCTGGTGATCCCAGAACTGAGTGGCAAATTGAAAGGTCACGCGCAACGCGTGCCAGTAAAAACGGGTTCCGT
GACGGAACTGGTTTCACTTTTGAGCCAAAAAGTGACGGTAGAAGAAGTGAATGATGTTATGAAAAAAGCCACTACTCATA
ATGAGTCTTTTGGTTATACCGATGAGGATATTGTTTCTTCTGATGTGATTGGGTCACATTTTGGCTCAGTGTTTGACGCC
ACTCAGACAGAAGTCACGGAAGTTGGTGATCTACAACTGGTTAAAACCGTCGCCTGGTACGATAACGAATATGGATTCGT
GACACAGCTGGTGCGTACTTTAGAAAAATTCATCAAGCTTTAA

Upstream 100 bases:

>100_bases
TTCCCAAAATAAATAAACAAAACGCTAACATAACCAGCTTTTATTAAAAATTCATTAATTATTCTCCCCAATGGTTCAGT
CACTTGGTCTTTAGTGCTCA

Downstream 100 bases:

>100_bases
ACCGAAAGCCGGGTAATAAAGAGCATTACCCGGCAAACAAGTTAGCCACTTAACGTAATGAACGGCTGTTTATCGCATCC
ATCAGTGTTTCATCGTGTTG

Product: glyceraldehyde-3-phosphate dehydrogenase C

Products: NA

Alternate protein names: GAPDH-C [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MWHCSPSHHGLCLEGKNPPSQSRQEITMSKIGINGFGRIGRLVLRRLLEVKSDVEVVAINDLTSPKILAYLLKHDSNYGQ
FPWSVDFTEDALIVDGKEIAVYAEKDARNIPWKAKGADIIVECTGFYTSGEKSQAHLDAGAKKVLISAPAGDMKTIVYHV
NEDTLAASDTIISVASCTTNCLAPMAKALHDSFGIKVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAK
AIGLVIPELSGKLKGHAQRVPVKTGSVTELVSLLSQKVTVEEVNDVMKKATTHNESFGYTDEDIVSSDVIGSHFGSVFDA
TQTEVTEVGDLQLVKTVAWYDNEYGFVTQLVRTLEKFIKL

Sequences:

>Translated_360_residues
MWHCSPSHHGLCLEGKNPPSQSRQEITMSKIGINGFGRIGRLVLRRLLEVKSDVEVVAINDLTSPKILAYLLKHDSNYGQ
FPWSVDFTEDALIVDGKEIAVYAEKDARNIPWKAKGADIIVECTGFYTSGEKSQAHLDAGAKKVLISAPAGDMKTIVYHV
NEDTLAASDTIISVASCTTNCLAPMAKALHDSFGIKVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAK
AIGLVIPELSGKLKGHAQRVPVKTGSVTELVSLLSQKVTVEEVNDVMKKATTHNESFGYTDEDIVSSDVIGSHFGSVFDA
TQTEVTEVGDLQLVKTVAWYDNEYGFVTQLVRTLEKFIKL
>Mature_360_residues
MWHCSPSHHGLCLEGKNPPSQSRQEITMSKIGINGFGRIGRLVLRRLLEVKSDVEVVAINDLTSPKILAYLLKHDSNYGQ
FPWSVDFTEDALIVDGKEIAVYAEKDARNIPWKAKGADIIVECTGFYTSGEKSQAHLDAGAKKVLISAPAGDMKTIVYHV
NEDTLAASDTIISVASCTTNCLAPMAKALHDSFGIKVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAK
AIGLVIPELSGKLKGHAQRVPVKTGSVTELVSLLSQKVTVEEVNDVMKKATTHNESFGYTDEDIVSSDVIGSHFGSVFDA
TQTEVTEVGDLQLVKTVAWYDNEYGFVTQLVRTLEKFIKL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7657116, Length=329, Percent_Identity=46.2006079027356, Blast_Score=282, Evalue=3e-76,
Organism=Homo sapiens, GI7669492, Length=325, Percent_Identity=45.2307692307692, Blast_Score=271, Evalue=6e-73,
Organism=Escherichia coli, GI1788079, Length=325, Percent_Identity=47.0769230769231, Blast_Score=283, Evalue=8e-78,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=39.6969696969697, Blast_Score=234, Evalue=9e-63,
Organism=Caenorhabditis elegans, GI17534677, Length=335, Percent_Identity=47.1641791044776, Blast_Score=279, Evalue=2e-75,
Organism=Caenorhabditis elegans, GI17534679, Length=335, Percent_Identity=47.4626865671642, Blast_Score=278, Evalue=3e-75,
Organism=Caenorhabditis elegans, GI32566163, Length=335, Percent_Identity=47.1641791044776, Blast_Score=277, Evalue=6e-75,
Organism=Caenorhabditis elegans, GI17568413, Length=330, Percent_Identity=47.5757575757576, Blast_Score=276, Evalue=1e-74,
Organism=Saccharomyces cerevisiae, GI6321631, Length=339, Percent_Identity=46.0176991150442, Blast_Score=292, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=339, Percent_Identity=46.0176991150442, Blast_Score=288, Evalue=8e-79,
Organism=Saccharomyces cerevisiae, GI6322409, Length=339, Percent_Identity=45.1327433628319, Blast_Score=284, Evalue=1e-77,
Organism=Drosophila melanogaster, GI19922412, Length=327, Percent_Identity=47.4006116207951, Blast_Score=293, Evalue=1e-79,
Organism=Drosophila melanogaster, GI85725000, Length=331, Percent_Identity=45.9214501510574, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI22023983, Length=331, Percent_Identity=45.9214501510574, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI17933600, Length=331, Percent_Identity=45.9214501510574, Blast_Score=278, Evalue=3e-75,
Organism=Drosophila melanogaster, GI18110149, Length=331, Percent_Identity=45.9214501510574, Blast_Score=278, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 39001; Mature: 39001

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWHCSPSHHGLCLEGKNPPSQSRQEITMSKIGINGFGRIGRLVLRRLLEVKSDVEVVAIN
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
DLTSPKILAYLLKHDSNYGQFPWSVDFTEDALIVDGKEIAVYAEKDARNIPWKAKGADII
CCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEE
VECTGFYTSGEKSQAHLDAGAKKVLISAPAGDMKTIVYHVNEDTLAASDTIISVASCTTN
EEEECCEECCCCCHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEECCHHEEEHHHHHHH
CLAPMAKALHDSFGIKVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAK
HHHHHHHHHHHHHCEEECCEEEEEEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHH
AIGLVIPELSGKLKGHAQRVPVKTGSVTELVSLLSQKVTVEEVNDVMKKATTHNESFGYT
HHHEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
DEDIVSSDVIGSHFGSVFDATQTEVTEVGDLQLVKTVAWYDNEYGFVTQLVRTLEKFIKL
CHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MWHCSPSHHGLCLEGKNPPSQSRQEITMSKIGINGFGRIGRLVLRRLLEVKSDVEVVAIN
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEC
DLTSPKILAYLLKHDSNYGQFPWSVDFTEDALIVDGKEIAVYAEKDARNIPWKAKGADII
CCCCHHHHHHHHHCCCCCCCCCEEECCCCCEEEECCCEEEEEECCCCCCCCCCCCCCEEE
VECTGFYTSGEKSQAHLDAGAKKVLISAPAGDMKTIVYHVNEDTLAASDTIISVASCTTN
EEEECCEECCCCCHHHHCCCCCEEEEECCCCCCEEEEEEECCCCEECCHHEEEHHHHHHH
CLAPMAKALHDSFGIKVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAK
HHHHHHHHHHHHHCEEECCEEEEEEECCCHHHHCCCCCCCCHHHHHHHHHCCCCCCCHHH
AIGLVIPELSGKLKGHAQRVPVKTGSVTELVSLLSQKVTVEEVNDVMKKATTHNESFGYT
HHHEEECCCCCCCCCCCEECCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCC
DEDIVSSDVIGSHFGSVFDATQTEVTEVGDLQLVKTVAWYDNEYGFVTQLVRTLEKFIKL
CHHHHHHHHHHHHHHHHHCCCHHHHHHCCCHHEEHHHHHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]