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The map label for this gene is yneH [H]

Identifier: 218548905

GI number: 218548905

Start: 1583014

End: 1583940

Strand: Direct

Name: yneH [H]

Synonym: EFER_1550

Alternate gene names: 218548905

Gene position: 1583014-1583940 (Clockwise)

Preceding gene: 218548904

Following gene: 218548906

Centisome position: 34.5

GC content: 51.56

Gene sequence:

>927_bases
GTGGCAGTTGCCATGGATAATTTCGTTTTAGAGTCTATTTTGCGTCAGGTGCGTCCACTTATTGGTAAGGGGAAAGTTGC
CGACTACATTCCGGCGTTAGCTACAGTTGACGGTAACCGTCTGGGAATGGCGATTTGTACTGTTGATGGGCAATGTTATC
AGGCCGGGGATGCTGAAGAGCGTTTCTCTATTCAGTCGATCTCCAAGGTGCTCAGTCTGGTAGTGGCGATGCGGCACTAC
AGTGAGGAGGAGATTTGGCAGCGAGTGGGTAAAGATCCCTCCGGTTCGCCGTTTAACTCGCTGGTACAACTGGAGATGGA
GCAGGGTATCCCACGCAACCCCTTTATCAATGCCGGGGCTCTGGTTGTATGCGATATGCTGCAAGGTCGTCTTAGTGCGC
CGCGTCAGCGAATGCTGGAAGTTGTTCGCGGGCTTAGCGGTGTAGCGGATATCGCCTATGACGGGGTGGTGGCGCGTTCT
GAATTTGAACACTCGGCGCGTAATGCGGCTATTGCCTGGCTGATGAAATCCTTTGGCAATTTCCATCATGATGTCGGTAC
TGTTCTGCAAAACTATTTTCACTACTGCGCACTGAAAATGAGTTGTGTGGAGCTTGCTCGCACTTTTGTTTTTCTGGCTA
ATCAGGGTAAGGCTATTCATATTGATGAACCAATAGTCACGCCAATGCAGGCGCGGCAAATTAATGCTCTGATGGCGACC
AGTGGCATGTATCAAAATGCCGGAGAGTTTGCCTGGCGCGTCGGTTTGCCTGCTAAGTCGGGTGTTGGCGGCGGAATTGT
GGCGATTATTCCCCATGAAATGGCAATTGCTGTCTGGAGCCCGGAGCTTGATCACGCGGGTAATTCACTGGCAGGTATTG
CTGCGCTTGAACAGTTAACACAAAGGCTGGGGCGTTCGGTGTACTGA

Upstream 100 bases:

>100_bases
GACCGTGTGGAAAGATCGTCTGTGAGTTAAGCTCCTGACGCAGAATATTCAGCTCTGTTATAATCGCGGGCCATTAAGTC
CTGCTGGCAAGGAGCAAGTT

Downstream 100 bases:

>100_bases
TGAATTCGTTTGATCCACTGTTTAAACGTTTATCCCGCTCTACATTTCGTTCTCGTTTTCGCCTTGGCGAGAAAGAGCGG
CAATACTGTTGGCAGAAAGG

Product: glutaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 308; Mature: 307

Protein sequence:

>308_residues
MAVAMDNFVLESILRQVRPLIGKGKVADYIPALATVDGNRLGMAICTVDGQCYQAGDAEERFSIQSISKVLSLVVAMRHY
SEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVADIAYDGVVARS
EFEHSARNAAIAWLMKSFGNFHHDVGTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPIVTPMQARQINALMAT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIIPHEMAIAVWSPELDHAGNSLAGIAALEQLTQRLGRSVY

Sequences:

>Translated_308_residues
MAVAMDNFVLESILRQVRPLIGKGKVADYIPALATVDGNRLGMAICTVDGQCYQAGDAEERFSIQSISKVLSLVVAMRHY
SEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVADIAYDGVVARS
EFEHSARNAAIAWLMKSFGNFHHDVGTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPIVTPMQARQINALMAT
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIIPHEMAIAVWSPELDHAGNSLAGIAALEQLTQRLGRSVY
>Mature_307_residues
AVAMDNFVLESILRQVRPLIGKGKVADYIPALATVDGNRLGMAICTVDGQCYQAGDAEERFSIQSISKVLSLVVAMRHYS
EEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVADIAYDGVVARSE
FEHSARNAAIAWLMKSFGNFHHDVGTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPIVTPMQARQINALMATS
GMYQNAGEFAWRVGLPAKSGVGGGIVAIIPHEMAIAVWSPELDHAGNSLAGIAALEQLTQRLGRSVY

Specific function: Unknown

COG id: COG2066

COG function: function code E; Glutaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutaminase family [H]

Homologues:

Organism=Homo sapiens, GI156104878, Length=274, Percent_Identity=37.5912408759124, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI20336214, Length=294, Percent_Identity=33.3333333333333, Blast_Score=162, Evalue=4e-40,
Organism=Escherichia coli, GI1787804, Length=308, Percent_Identity=93.8311688311688, Blast_Score=604, Evalue=1e-174,
Organism=Escherichia coli, GI1786693, Length=286, Percent_Identity=37.7622377622378, Blast_Score=192, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17507019, Length=291, Percent_Identity=37.8006872852234, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI193204073, Length=309, Percent_Identity=36.2459546925566, Blast_Score=181, Evalue=5e-46,
Organism=Caenorhabditis elegans, GI193204075, Length=311, Percent_Identity=36.0128617363344, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17532727, Length=308, Percent_Identity=32.4675324675325, Blast_Score=169, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24653162, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281363239, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281363241, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24653158, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653164, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI116008307, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653156, Length=285, Percent_Identity=36.140350877193, Blast_Score=188, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24653166, Length=285, Percent_Identity=36.140350877193, Blast_Score=187, Evalue=6e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR015868 [H]

Pfam domain/function: PF04960 Glutaminase [H]

EC number: =3.5.1.2 [H]

Molecular weight: Translated: 33533; Mature: 33402

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVAMDNFVLESILRQVRPLIGKGKVADYIPALATVDGNRLGMAICTVDGQCYQAGDAEE
CCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHH
RFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
LVVCDMLQGRLSAPRQRMLEVVRGLSGVADIAYDGVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
FHHDVGTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPIVTPMQARQINALMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIIPHEMAIAVWSPELDHAGNSLAGIAALEQLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHCCCHHHHHHHHHHHH
QRLGRSVY
HHHCCCCC
>Mature Secondary Structure 
AVAMDNFVLESILRQVRPLIGKGKVADYIPALATVDGNRLGMAICTVDGQCYQAGDAEE
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHH
RFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLVQLEMEQGIPRNPFINAGA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCH
LVVCDMLQGRLSAPRQRMLEVVRGLSGVADIAYDGVVARSEFEHSARNAAIAWLMKSFGN
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCC
FHHDVGTVLQNYFHYCALKMSCVELARTFVFLANQGKAIHIDEPIVTPMQARQINALMAT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHH
SGMYQNAGEFAWRVGLPAKSGVGGGIVAIIPHEMAIAVWSPELDHAGNSLAGIAALEQLT
CCCCCCCCCEEEEECCCCCCCCCCCEEEEECCCEEEEEECCCHHHCCCHHHHHHHHHHHH
QRLGRSVY
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]