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The map label for this gene is cfa [H]

Identifier: 218548744

GI number: 218548744

Start: 1419340

End: 1420488

Strand: Reverse

Name: cfa [H]

Synonym: EFER_1383

Alternate gene names: 218548744

Gene position: 1420488-1419340 (Counterclockwise)

Preceding gene: 218548745

Following gene: 218548742

Centisome position: 30.96

GC content: 48.22

Gene sequence:

>1149_bases
ATGAGTTCATCGTGTATAGAAGAAGTTAGCGTACCGGATGATGACTGGTATCGCATCGCCAACGAATTACTTAGCCGTGC
TGACATTACAATCAATGGCTCAGCACCGGCGGATATTCGTGTCAAAAACCCCGATTTTTTTAAACGCGTTTTGCAGGAAG
GATCGCTGGGCTTGGGTGAGAGTTACATGGATGGCTGGTGGGAATGCGACAGACTCGATATGTTCTTTAGCAAAGTCCTG
CGCGCCGGTCTGGAAAACCAACTCCCCCGCCATCTCAAAGACACACTCCGTATTGCAAGCGCTCGCTTGTTCAACCTGCA
AAGTAAAAAACGCGCCTGGATAGTGGGCAAAGAACATTACGATTTGGGTAATGATCTATTCAGCCGAATGCTTGATCCCT
ACATGCAATATTCCTGCGCTTACTGGAAAGATGCCGATAACCTGGAAGCTGCCCAGCAAGCGAAGTTGAAAATGATTTGC
GAAAAATTGCATTTGAAACCAGGGATGCGGGTTCTGGATATCGGCTGTGGCTGGGGCGGCTTGTCGCAGTATCTTGCCAC
TCATTATGGTGCCAGTGTTGTTGGGGTAACGATTTCTGCTGAGCAACAAAAAATGGCTCAGGAACGTTGCGCCGGGCTAG
ATGTGGAGATTCTGCTGGAAGATTATCGTGATCTTAACGACCAGTTTGATCGGATCGTTTCGGTTGGGATGTTCGAACAT
GTCGGGCCAAAGAATTACAACACTTACTTCGAAGTGGTAGACCGTAATTTAAAACCAGACGGTTTATTCCTGCTACACAC
CATCGGTTCCAAAAAGACCGACCATAATGTTGATCCGTGGATTAACAAATACATTTTCCCTAACGGTTGCCTTCCCTCCG
TACGGCAAATTGCCTGTGCCAGTGAGCCACATTTCATTATGGAAGACTGGCATAACTTTGGGGCAGATTATGACACGACG
CTGATGGCATGGTATGAACGCTTTCTTGCCGCCTGGCCAGAAATTGCCGATAACTATAGCGAACGCTTCAAGCGTATGTT
TACTTACTACCTGAATGCCTGTGCCGGAGCGTTTCGCGCCCGCGATATTCAGCTCTGGCAGGTCGTTTTCTCACGTGGTG
TTGAACACGGTTTACGCGTTCCTCGCTAA

Upstream 100 bases:

>100_bases
ATTCCAGGCTCACGGAATTTTTCCGTGAGATTTCTCACAAAGCCATAAAAGCGACTACGCTGTTTTAAGGTTCTGATCAC
CGACCAGTGATGGAGAAGCT

Downstream 100 bases:

>100_bases
CTAAACCCCCCGCGAAATGCGGGGGTAGCCATCATTGCTTTCAGACCTGCGTCTCGCTGCCTGGCTCTTTCAACGCATTT
TCGCGCGCAGCCAGTACGCG

Product: cyclopropane fatty acyl phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MSSSCIEEVSVPDDDWYRIANELLSRADITINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVL
RAGLENQLPRHLKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADNLEAAQQAKLKMIC
EKLHLKPGMRVLDIGCGWGGLSQYLATHYGASVVGVTISAEQQKMAQERCAGLDVEILLEDYRDLNDQFDRIVSVGMFEH
VGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHNVDPWINKYIFPNGCLPSVRQIACASEPHFIMEDWHNFGADYDTT
LMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVEHGLRVPR

Sequences:

>Translated_382_residues
MSSSCIEEVSVPDDDWYRIANELLSRADITINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVL
RAGLENQLPRHLKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADNLEAAQQAKLKMIC
EKLHLKPGMRVLDIGCGWGGLSQYLATHYGASVVGVTISAEQQKMAQERCAGLDVEILLEDYRDLNDQFDRIVSVGMFEH
VGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHNVDPWINKYIFPNGCLPSVRQIACASEPHFIMEDWHNFGADYDTT
LMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVEHGLRVPR
>Mature_381_residues
SSSCIEEVSVPDDDWYRIANELLSRADITINGSAPADIRVKNPDFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLR
AGLENQLPRHLKDTLRIASARLFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPYMQYSCAYWKDADNLEAAQQAKLKMICE
KLHLKPGMRVLDIGCGWGGLSQYLATHYGASVVGVTISAEQQKMAQERCAGLDVEILLEDYRDLNDQFDRIVSVGMFEHV
GPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHNVDPWINKYIFPNGCLPSVRQIACASEPHFIMEDWHNFGADYDTTL
MAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVEHGLRVPR

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=382, Percent_Identity=92.4083769633508, Blast_Score=746, Evalue=0.0,
Organism=Caenorhabditis elegans, GI133904226, Length=385, Percent_Identity=30.1298701298701, Blast_Score=146, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 44023; Mature: 43891

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSSCIEEVSVPDDDWYRIANELLSRADITINGSAPADIRVKNPDFFKRVLQEGSLGLGE
CCCHHHHHCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEECCHHHHHHHHHCCCCCCCH
SYMDGWWECDRLDMFFSKVLRAGLENQLPRHLKDTLRIASARLFNLQSKKRAWIVGKEHY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHC
DLGNDLFSRMLDPYMQYSCAYWKDADNLEAAQQAKLKMICEKLHLKPGMRVLDIGCGWGG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHH
LSQYLATHYGASVVGVTISAEQQKMAQERCAGLDVEILLEDYRDLNDQFDRIVSVGMFEH
HHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHNVDPWINKYIFPNGCLPSVRQIACA
CCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHC
SEPHFIMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVVFSRGVEHGLRVPR
HHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SSSCIEEVSVPDDDWYRIANELLSRADITINGSAPADIRVKNPDFFKRVLQEGSLGLGE
CCHHHHHCCCCCHHHHHHHHHHHHHCCEEECCCCCCCEEECCHHHHHHHHHCCCCCCCH
SYMDGWWECDRLDMFFSKVLRAGLENQLPRHLKDTLRIASARLFNLQSKKRAWIVGKEHY
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHC
DLGNDLFSRMLDPYMQYSCAYWKDADNLEAAQQAKLKMICEKLHLKPGMRVLDIGCGWGG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHH
LSQYLATHYGASVVGVTISAEQQKMAQERCAGLDVEILLEDYRDLNDQFDRIVSVGMFEH
HHHHHHHHCCCEEEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VGPKNYNTYFEVVDRNLKPDGLFLLHTIGSKKTDHNVDPWINKYIFPNGCLPSVRQIACA
CCCCCCCHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHC
SEPHFIMEDWHNFGADYDTTLMAWYERFLAAWPEIADNYSERFKRMFTYYLNACAGAFRA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDIQLWQVVFSRGVEHGLRVPR
HHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]