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The map label for this gene is lsrR [H]

Identifier: 218547844

GI number: 218547844

Start: 445265

End: 446266

Strand: Direct

Name: lsrR [H]

Synonym: EFER_0434

Alternate gene names: 218547844

Gene position: 445265-446266 (Clockwise)

Preceding gene: 218547843

Following gene: 218547845

Centisome position: 9.7

GC content: 50.0

Gene sequence:

>1002_bases
ATGTCATCCCTCTTTTCTTCTATGGAGAACCCGCCTCGCATGGACAAATCCAGCCAGACTCAGGATTTTGAACTACTCAC
CGAGATAGCCATTGCGTACTACTGCGATGAGGTCACACAAGAAGAGATAGCCAATCGATTCGGTTTTTCACGGATTAAAA
TTGGTCGGTTACTAAAGCGTGCGAAAGAAGAGGGCATTGTCGAGATTAACGTTCGTTATCATCCGGTTTTCAGCACCCAG
CTTGAAAAACAGATGCAGGAACGTTTCCCGATCTCCCGCGCTTTGATTGCTCTTGATCATAATGATGAAGATGAACAGCG
CCGCCAGGTGGCAGCGCTGGTTTCTAATTATCTCGCCAATAATCTGCGTGACAATATGGTCGTCGCGGTCGGGCAGGGGC
GTAATGTGGCGGCAGTCGCTGAACACATCAGCCCAATCCAGACAAAAGATTGTCATTTTGTTTGCGGTATTGGCGGTACG
CATCGTCCTGGCGATATCATCAACGCCGACCATATCAGCCGTCTTCTGGCGAAGAAATTTGGCGGCAGCAGCGAATCGCT
CTATGCGCCCGCCTACGTTGAAAATCCCGAGCTTAAAGTGGCGTTGATGCGTAATGGCACCATAAAGGAGACGCTGGATC
GCGCACGCAAAGCGGATATCGCGCTGGTAGGTATTGGTGATATGAATGAGAACAGCTATATGGTGAAGCTGGGCTGGTTT
ACGCCGCAGGAGATCAACGATGCCAGTCTCAATCAGGGGGTCACGGGCGATATAGCGGGGTATGATTTCTTCAACGCCCA
GGGGAAACATGTCAATACCGTGATGGACGATCGCGTCATCGGGTTGAGTATTGAAGAGCTACGCCAGATCCCGTGCGTTA
TTGCTATCGCCTCCGAGAACACCAAAGCAATGTCAATTATGGGAGCATTACGTACTGGTGTGATTGATATTATCGCCACC
AGTGCGCGCAATATCCGCACTATTTTGAGTATGACGCAATAG

Upstream 100 bases:

>100_bases
CCGCATTAAACGTTGATACAACGCTCCGCTATCCCCCTGATGGCGGAGCAGATCTTTTTCTCTGCGTCAGCAGATCTGAT
ACAATTTTTGCTAAACGGCA

Downstream 100 bases:

>100_bases
TTTGGGATTAATAAATCCAGTGGGTGATATTGCCAATTGTGTAGGTATATAAATCGAAACACAACGACAGGCGGCTATCC
TGACTCTTTCATGTGGCTCT

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MSSLFSSMENPPRMDKSSQTQDFELLTEIAIAYYCDEVTQEEIANRFGFSRIKIGRLLKRAKEEGIVEINVRYHPVFSTQ
LEKQMQERFPISRALIALDHNDEDEQRRQVAALVSNYLANNLRDNMVVAVGQGRNVAAVAEHISPIQTKDCHFVCGIGGT
HRPGDIINADHISRLLAKKFGGSSESLYAPAYVENPELKVALMRNGTIKETLDRARKADIALVGIGDMNENSYMVKLGWF
TPQEINDASLNQGVTGDIAGYDFFNAQGKHVNTVMDDRVIGLSIEELRQIPCVIAIASENTKAMSIMGALRTGVIDIIAT
SARNIRTILSMTQ

Sequences:

>Translated_333_residues
MSSLFSSMENPPRMDKSSQTQDFELLTEIAIAYYCDEVTQEEIANRFGFSRIKIGRLLKRAKEEGIVEINVRYHPVFSTQ
LEKQMQERFPISRALIALDHNDEDEQRRQVAALVSNYLANNLRDNMVVAVGQGRNVAAVAEHISPIQTKDCHFVCGIGGT
HRPGDIINADHISRLLAKKFGGSSESLYAPAYVENPELKVALMRNGTIKETLDRARKADIALVGIGDMNENSYMVKLGWF
TPQEINDASLNQGVTGDIAGYDFFNAQGKHVNTVMDDRVIGLSIEELRQIPCVIAIASENTKAMSIMGALRTGVIDIIAT
SARNIRTILSMTQ
>Mature_332_residues
SSLFSSMENPPRMDKSSQTQDFELLTEIAIAYYCDEVTQEEIANRFGFSRIKIGRLLKRAKEEGIVEINVRYHPVFSTQL
EKQMQERFPISRALIALDHNDEDEQRRQVAALVSNYLANNLRDNMVVAVGQGRNVAAVAEHISPIQTKDCHFVCGIGGTH
RPGDIINADHISRLLAKKFGGSSESLYAPAYVENPELKVALMRNGTIKETLDRARKADIALVGIGDMNENSYMVKLGWFT
PQEINDASLNQGVTGDIAGYDFFNAQGKHVNTVMDDRVIGLSIEELRQIPCVIAIASENTKAMSIMGALRTGVIDIIATS
ARNIRTILSMTQ

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=312, Percent_Identity=26.6025641025641, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082414, Length=293, Percent_Identity=25.2559726962457, Blast_Score=94, Evalue=1e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 36964; Mature: 36832

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLFSSMENPPRMDKSSQTQDFELLTEIAIAYYCDEVTQEEIANRFGFSRIKIGRLLKR
CCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AKEEGIVEINVRYHPVFSTQLEKQMQERFPISRALIALDHNDEDEQRRQVAALVSNYLAN
HHHCCEEEEEEEEECCHHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHH
NLRDNMVVAVGQGRNVAAVAEHISPIQTKDCHFVCGIGGTHRPGDIINADHISRLLAKKF
CCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GGSSESLYAPAYVENPELKVALMRNGTIKETLDRARKADIALVGIGDMNENSYMVKLGWF
CCCCCCEECCEEECCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECC
TPQEINDASLNQGVTGDIAGYDFFNAQGKHVNTVMDDRVIGLSIEELRQIPCVIAIASEN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHCCEEECCCHHHHHCCCEEEEEECCC
TKAMSIMGALRTGVIDIIATSARNIRTILSMTQ
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure 
SSLFSSMENPPRMDKSSQTQDFELLTEIAIAYYCDEVTQEEIANRFGFSRIKIGRLLKR
CHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
AKEEGIVEINVRYHPVFSTQLEKQMQERFPISRALIALDHNDEDEQRRQVAALVSNYLAN
HHHCCEEEEEEEEECCHHHHHHHHHHHHCCHHHEEEEECCCCCHHHHHHHHHHHHHHHHH
NLRDNMVVAVGQGRNVAAVAEHISPIQTKDCHFVCGIGGTHRPGDIINADHISRLLAKKF
CCCCCEEEEECCCCCHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHC
GGSSESLYAPAYVENPELKVALMRNGTIKETLDRARKADIALVGIGDMNENSYMVKLGWF
CCCCCCEECCEEECCCCEEEEEECCCCHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECC
TPQEINDASLNQGVTGDIAGYDFFNAQGKHVNTVMDDRVIGLSIEELRQIPCVIAIASEN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECHHHCCEEECCCHHHHHCCCEEEEEECCC
TKAMSIMGALRTGVIDIIATSARNIRTILSMTQ
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA