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The map label for this gene is norR [H]

Identifier: 218547783

GI number: 218547783

Start: 381780

End: 383294

Strand: Direct

Name: norR [H]

Synonym: EFER_0369

Alternate gene names: 218547783

Gene position: 381780-383294 (Clockwise)

Preceding gene: 218547780

Following gene: 218547785

Centisome position: 8.32

GC content: 56.57

Gene sequence:

>1515_bases
ATGAGTTTTTCCGTTGATGTGCTGGCGAATATCGCCATCGAATTGCAGCGTGGGATTGGTCATCAGGATCGTTTTCAGCG
CCTGATCACCACGTTGCGTCAGGTGCTGGAGTGCGATGCGTCTGCGTTGCTACGTTACGACTCGCGGCAGTTTATTCCGC
TTGCCATCGACGGACTGGCGAAGGATGTACTCGGTAGACGCTTTGCCCTGGAAGGGCATCCGCGGCTGGAAGCGATAGCC
CGCGCCGGGGACGTGGTGCGTTTTCCCGCAGACAGCGAATTGCCCGATCCCTATGACGGTTTGATTCCCGGGCAGGAGAG
TCTGAAGGTTCACGCCTGCGTTGGTCTGCCGTTATTTGCCGGACAAAACCTGATCGGTGCATTGACACTCGACGGGATGC
AGCCCGATCAGTTCGATGTTTTCAGCGACGAAGAGTTACGGCTGATTGCCGCGCTGGCGGCGGGAGCGTTAAGCAATGCG
TTGCTGATTGAACAACTGGAAAGTCAGAATATGCTGCCGGGCGATGCCGCGCCGTTTGAAGCGCTGAAAGAGACGCAGAT
GATCGGCCTGTCGCCAGGCATGACGCAATTGAAAAAAGAGATTGAGATTGTGGCGGCGTCCGATCTCAACGTCCTAATCA
GTGGTGAGACGGGAACGGGTAAGGAGCTGGTGGCGAAAGCGATTCATGAAGCCTCGCCACGGGCGGTGAATCCGTTAGTC
TATCTCAACTGTGCCGCACTGCCGGAAAGTGTGGCGGAAAGTGAGTTGTTCGGGCACGTGAAAGGGGCGTTTACTGGCGC
TATCAGTAACCGCAGTGGGAAGTTTGAAATGGCGGATAACGGCACGCTGTTTCTGGATGAGATCGGCGAGTTGTCGTTGA
CATTGCAGGCCAAGCTGCTGCGCGTGTTGCAGTATGGCGATATTCAGCGTGTTGGCGATGACCGCAGTTTGCGGGTCGAT
GTGCGCGTGCTGGCGGCGACTAACCGCGACTTGCGCGAAGAGGTGCTGGCAGGGCGATTTCGTGCCGACTTGTTTCATCG
CCTGAGTGTGTTTCCGCTTTTGGTGCCGCCGCTGCGTGAGCGGGGTGATGACGTCATTCTTCTGGCGGGGTATTTCTGTG
AGCAGTGTCGTTTGCGGCTGGGGCTCTCCCGCGTGGTATTAAGTGCCGGGGCGCGGAATTTATTGCAACACTATAGTTTT
CCGGGAAACGTGCGCGAACTGGAACATGCTATTCATCGGGCGGTAGTACTGTCGAGAGCCACTCGCAGCGGCGATGAAGT
GATTCTTGAAGCGCAACATTTTGCTTTTCCTGAGGTGACGTTGCCGCCGCCAGAAGCGGCGGCGGTGCCTATCGTTAAGC
AAAACCTGCGTGAAGCGACAGAAGAGTTCCAGCGTAAAACCATTCGCCAGGCACTGGCACAAAATCATCACAACTGGGCT
GCCAGCGCACGGATGCTGGAAACCGACGTCGCCAACTTGCATCGGTTGGCGAAACGTCTGGGGCTGAAGGATTAA

Upstream 100 bases:

>100_bases
TATATAAATAAAATTATGCTCATTAGTGAGCAGTCAAAATGACTATCAATAAAATGGTCGATATGACAATATCTATAGTC
AAATTGACAGCGAGGCAAAG

Downstream 100 bases:

>100_bases
ATAATCCCGGCCTGATAGAAATCCTGCAGGTTAATCGCGCCGACGAGTTTGCCGTTTTCATCTACCACCGGTGCGGCGGT
GATTTTGCGTTTCATCAGGA

Product: anaerobic nitric oxide reductase transcription regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLTLQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLLVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSF
PGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEEFQRKTIRQALAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD

Sequences:

>Translated_504_residues
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIA
RAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
LLIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLTLQAKLLRVLQYGDIQRVGDDRSLRVD
VRVLAATNRDLREEVLAGRFRADLFHRLSVFPLLVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSF
PGNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEEFQRKTIRQALAQNHHNWA
ASARMLETDVANLHRLAKRLGLKD
>Mature_503_residues
SFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIAR
AGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNAL
LIEQLESQNMLPGDAAPFEALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVY
LNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLTLQAKLLRVLQYGDIQRVGDDRSLRVDV
RVLAATNRDLREEVLAGRFRADLFHRLSVFPLLVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSFP
GNVRELEHAIHRAVVLSRATRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEEFQRKTIRQALAQNHHNWAA
SARMLETDVANLHRLAKRLGLKD

Specific function: Required for the expression of anaerobic nitric oxide (NO) reductase, acts as a transcriptional activator for at least the norVW operon. Activation also requires sigma-54 [H]

COG id: COG3604

COG function: function code KT; Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082152, Length=504, Percent_Identity=97.2222222222222, Blast_Score=952, Evalue=0.0,
Organism=Escherichia coli, GI1789087, Length=357, Percent_Identity=41.1764705882353, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=47.4683544303797, Blast_Score=255, Evalue=6e-69,
Organism=Escherichia coli, GI1788550, Length=299, Percent_Identity=46.1538461538462, Blast_Score=251, Evalue=1e-67,
Organism=Escherichia coli, GI1790437, Length=231, Percent_Identity=55.8441558441558, Blast_Score=249, Evalue=3e-67,
Organism=Escherichia coli, GI1788905, Length=316, Percent_Identity=39.873417721519, Blast_Score=225, Evalue=6e-60,
Organism=Escherichia coli, GI1790299, Length=336, Percent_Identity=40.7738095238095, Blast_Score=224, Evalue=1e-59,
Organism=Escherichia coli, GI1789233, Length=333, Percent_Identity=39.3393393393393, Blast_Score=213, Evalue=2e-56,
Organism=Escherichia coli, GI87081872, Length=316, Percent_Identity=38.9240506329114, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI1787583, Length=334, Percent_Identity=37.125748502994, Blast_Score=207, Evalue=2e-54,
Organism=Escherichia coli, GI1786524, Length=249, Percent_Identity=46.5863453815261, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789828, Length=247, Percent_Identity=36.0323886639676, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI87081858, Length=207, Percent_Identity=34.2995169082126, Blast_Score=106, Evalue=3e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003018
- InterPro:   IPR009057
- InterPro:   IPR002078 [H]

Pfam domain/function: PF01590 GAF; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 55286; Mature: 55155

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLTLQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLLVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
RGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLSRA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEEFQRKTIRQALAQNHHNWA
CCCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALLRYDSRQFIPLAIDGLA
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEHHHHHHH
KDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLIPGQESLKVHACVGLPLFA
HHHHCCEEECCCCCHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHC
GQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNALLIEQLESQNMLPGDAAPFE
CCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHH
ALKETQMIGLSPGMTQLKKEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLV
HHHHHHHCCCCCCHHHHHHHHEEEEECCCEEEEECCCCCCHHHHHHHHHHCCCCCCCCEE
YLNCAALPESVAESELFGHVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLTLQAKLL
EEEEHHCCHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCCEEEEECCCCHHHHHHHHHH
RVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLLVPPLRE
HHHHCCCHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHC
RGDDVILLAGYFCEQCRLRLGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLSRA
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
TRSGDEVILEAQHFAFPEVTLPPPEAAAVPIVKQNLREATEEFQRKTIRQALAQNHHNWA
CCCCCCEEEEEHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASARMLETDVANLHRLAKRLGLKD
HHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA