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The map label for this gene is norW [H]

Identifier: 218547781

GI number: 218547781

Start: 379024

End: 380157

Strand: Reverse

Name: norW [H]

Synonym: EFER_0367

Alternate gene names: 218547781

Gene position: 380157-379024 (Counterclockwise)

Preceding gene: 218547782

Following gene: 218547777

Centisome position: 8.28

GC content: 55.03

Gene sequence:

>1134_bases
ATGAGCAACGGCATTGTGATCATTGGTTCAGGCTTCGCCGCCCGCCAACTGGTGAAAAATATTCGTAAACAGGATACCGG
TATTCCATTGACCCTGATTGCCGCCGACAGCATGGATGAGTACAACAAACCTGATCTTAGCCATGTGATCAGTCAGGGGC
AACGTGCCGACGACCTTACCCGCCAGACGGCGGGTGAATTTGCCGAGCAGTTTAATCTGCGCCTGTTTCCGCACACCTGG
GTGACGGATATCGATGCCGAAGCCCATGTGGTGAAAAGCCAGAATAATCAGTGGCAATACGACAAGCTAGTGCTGGCAAC
CGGTGCCAACGCCTTTGTCCCGCCGGTGCCTGGGCGTGAGTTAATGCTGACGTTAAATAGTCAGCAAGAGTATCGCGCCT
GTGAAACACAGCTGCGGGATGCCCGACGGGTGTTGATTGTAGGCGGTGGTTTGATTGGTAGCGAACTGGCGATGGATTTT
TGTCGGGCAGGCAAAGCGGTCACGCTAATCGACAACGCTGCCAGTATTCTGGCGTCGTTAATGCCACCGGAAGTAAGCAG
TCGCTTACAGCATCGGTTGACGGAGATGGGCGTTCATCTGCTGTTGAAATCTCAGTTGCAGGGGCTGGAAAAAACGAATT
CTGGCATTCTGGCAACGCTGGACCGCCAGCGCAGCACCGAAGTGGATGCGGTAATTGCCGCCACCGGACTGCGCCCGGAA
ACCGCCCTGGCACGACGCGCCGGGCTGACGATTAATCGCGGCGTTTGCGTCGATAGCTATCTGCAAACCAGTAATGCCGA
TATTTACGCGCTGGGCGATTGCGCGGAAATTAACGGTCAGGTATTGCCGTTCCTCCAGCCGATTCAACTTAGCGCGATGG
TGCTGGCAAAAAATCTTCTCGGCAATAACACGCCGCTGAAACTCCCGGCGATGCTGGTGAAAATCAAAACGCCGGAATTA
CCGCTGCATCTGGCAGGGGAAACCCAGCGTCGGGATTTGCGCTGGCAGATTTGTACCGAAAGCCAGGGAATGGTGGCGCG
CGGCGTTGACGATGCCGACCAGCTTCGCGCCTTTGTAGTCAGTGAGGATCGGATGAAAGAGGCGTTTGGATTGTTGAAAA
CCTTGCCGATGTAG

Upstream 100 bases:

>100_bases
TTGCGCCAGGAACGCCGTGGAGTGAAGTCCCGGATAACTTCCTGTGCCCGGAATGCTCCCTCGGCAAAGACGTCTTTGAC
GAACTGGCATCGGAGGCAAA

Downstream 100 bases:

>100_bases
GCAGGCTAGTGTGCCCAAAATGTCGGATGCGACGCTGGCGCGTCTTATCCGACCTACGGGGAGCGAATGTGTAGGCCGGA
TAAGGCGTTCACGCCGCATC

Product: nitric oxide reductase

Products: NAD; reduced flavorubredoxin; H2O [C]

Alternate protein names: Flavorubredoxin reductase; FlRd-reductase; FlavoRb reductase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTW
VTDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPE
TALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPEL
PLHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM

Sequences:

>Translated_377_residues
MSNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTW
VTDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPE
TALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPEL
PLHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM
>Mature_376_residues
SNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWV
TDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFC
RAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPET
ALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELP
LHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM

Specific function: One of at least two accessory proteins for anaerobic nitric oxide (NO) reductase. Reduces the rubredoxin moiety of NO reductase [H]

COG id: COG0446

COG function: function code R; Uncharacterized NAD(FAD)-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI4757732, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI22202629, Length=214, Percent_Identity=26.1682242990654, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789065, Length=377, Percent_Identity=96.2864721485411, Blast_Score=741, Evalue=0.0,
Organism=Escherichia coli, GI1789765, Length=323, Percent_Identity=25.3869969040248, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788892, Length=274, Percent_Identity=27.007299270073, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787352, Length=246, Percent_Identity=29.6747967479675, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17559934, Length=276, Percent_Identity=25.3623188405797, Blast_Score=85, Evalue=7e-17,
Organism=Drosophila melanogaster, GI24639257, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281359715, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281359713, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639250, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18543267, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24639252, Length=373, Percent_Identity=23.0563002680965, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: NA

Molecular weight: Translated: 41289; Mature: 41158

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLT
CCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCHHHHH
RQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRE
HHHHHHHHHHCCCEECCCCCEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCE
LMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASL
EEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
MPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEEEECCCCCH
TALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLL
HHHHHHCCCEEECCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GNNTPLKLPAMLVKIKTPELPLHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVV
CCCCCCEECEEEEEEECCCCCEEECCCCCCCCCEEEEECCCCCCEECCCCCHHHHHHHHH
SEDRMKEAFGLLKTLPM
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNGIVIIGSGFAARQLVKNIRKQDTGIPLTLIAADSMDEYNKPDLSHVISQGQRADDLT
CCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCHHHHH
RQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDKLVLATGANAFVPPVPGRE
HHHHHHHHHHCCCEECCCCCEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCE
LMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDFCRAGKAVTLIDNAASILASL
EEEEECCCHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHH
MPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTNSGILATLDRQRSTEVDAVIAATGLRPE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHEEEEECCCCCH
TALARRAGLTINRGVCVDSYLQTSNADIYALGDCAEINGQVLPFLQPIQLSAMVLAKNLL
HHHHHHCCCEEECCCCHHHHHHCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHH
GNNTPLKLPAMLVKIKTPELPLHLAGETQRRDLRWQICTESQGMVARGVDDADQLRAFVV
CCCCCCEECEEEEEEECCCCCEEECCCCCCCCCEEEEECCCCCCEECCCCCHHHHHHHHH
SEDRMKEAFGLLKTLPM
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADH; oxidized flavorubredoxin; O2 [C]

Specific reaction: NADH + oxidized flavorubredoxin + O2 = NAD + reduced flavorubredoxin + H2O [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA