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The map label for this gene is agaR [H]

Identifier: 218547758

GI number: 218547758

Start: 355597

End: 356532

Strand: Direct

Name: agaR [H]

Synonym: EFER_0343

Alternate gene names: 218547758

Gene position: 355597-356532 (Clockwise)

Preceding gene: 218547757

Following gene: 218547759

Centisome position: 7.75

GC content: 49.79

Gene sequence:

>936_bases
GTGACCCGCGGGGGCGTTTTCGCCCCCCTTTATGATATTCTTATTACTCGCTGCCAATCCCGGCAATACAAACCCGGAAG
TGTTATGACGCAAATGTCTCAGGATCATTCTCTCAATCTCTTTCTTGCTGAAACGCTGCCAGGCGATAGCCGACAGGCAC
GGCAGCTGGCGCGTCGTCAGCTCATTGTTGAAGCGGTTATGGCGGAAGGGGCGATTCGTATTGAGGAGATCACTGAGCGC
TACGGTATTAGTTTAATGACCGCCCACCGGGATATCGATGAGCTTGCCGAACGTGGACTGCTGCATAAATCCCGTGGCGT
GGTTTCGGCAACATCGACCAGCCTGGTTGAATCCAGCGATCTCTATCGCGCAACCCGTCAACTGGAAGAGAAACAGGCTA
TCGCCGAAGTGGCGGTGACTTATCTTGAACCTGGGCAGGCTATTTTTCTCGATGACTCAACAACGGTATTTCAGATGGCG
CGTTACCTGCCAGCCAGAACCCCTCTGACCGTGATTACTAATTCATTGACCTTAATGAATGAACTTAAAAACATCCGGGA
TTTAACCTTATTAGGGCTGGGGGGGCAGTACCACAACTGGTGCAATGCGTTTATGGGGCATATGACACGAGAAGAAATTG
CCGGCCTGCGGGCGAATACCTTTTTTGTCAGTATGTCGGCAATTATGGGCGATACGGTATTTCATCAGTCAGCCGAAACC
GTAGAAACGAAACGGGCGATGTTTGAATCTGCAGAAAAGCGTTTCTTATTGATGGACCATACTAAATTTGAGCGCCGCGC
TTTGTATCAGTTCGCTCATTTAAGGGAGTTTGATGCGGTCATTGTTAATCAGGGGACGCCTGTGCAGGTATTACGCCACC
TTAAAGATTTGGGGGTAAATGTGGTTGTCGCTGGAATGAAAGTGAAAGCGGAATAG

Upstream 100 bases:

>100_bases
ACAGGCGCGTCATCCGAGAAACAGTTATTTGACTGTATTTTAATCACTAAAGAGAACGCAGCTAAAATTACGGCACCGTT
TATGTTGTCAGAATAGTGCC

Downstream 100 bases:

>100_bases
TAATTATGCGGCGAACGGTTGGGAAATGTTAAAGCGCTATGCTTCTCAGACATACTGATTAATCACCCCTTTCTTCGCAC
CAATATTCAGTTGTCTCCTC

Product: transcriptional regulator of sugar metabolism, DeoR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 310

Protein sequence:

>311_residues
MTRGGVFAPLYDILITRCQSRQYKPGSVMTQMSQDHSLNLFLAETLPGDSRQARQLARRQLIVEAVMAEGAIRIEEITER
YGISLMTAHRDIDELAERGLLHKSRGVVSATSTSLVESSDLYRATRQLEEKQAIAEVAVTYLEPGQAIFLDDSTTVFQMA
RYLPARTPLTVITNSLTLMNELKNIRDLTLLGLGGQYHNWCNAFMGHMTREEIAGLRANTFFVSMSAIMGDTVFHQSAET
VETKRAMFESAEKRFLLMDHTKFERRALYQFAHLREFDAVIVNQGTPVQVLRHLKDLGVNVVVAGMKVKAE

Sequences:

>Translated_311_residues
MTRGGVFAPLYDILITRCQSRQYKPGSVMTQMSQDHSLNLFLAETLPGDSRQARQLARRQLIVEAVMAEGAIRIEEITER
YGISLMTAHRDIDELAERGLLHKSRGVVSATSTSLVESSDLYRATRQLEEKQAIAEVAVTYLEPGQAIFLDDSTTVFQMA
RYLPARTPLTVITNSLTLMNELKNIRDLTLLGLGGQYHNWCNAFMGHMTREEIAGLRANTFFVSMSAIMGDTVFHQSAET
VETKRAMFESAEKRFLLMDHTKFERRALYQFAHLREFDAVIVNQGTPVQVLRHLKDLGVNVVVAGMKVKAE
>Mature_310_residues
TRGGVFAPLYDILITRCQSRQYKPGSVMTQMSQDHSLNLFLAETLPGDSRQARQLARRQLIVEAVMAEGAIRIEEITERY
GISLMTAHRDIDELAERGLLHKSRGVVSATSTSLVESSDLYRATRQLEEKQAIAEVAVTYLEPGQAIFLDDSTTVFQMAR
YLPARTPLTVITNSLTLMNELKNIRDLTLLGLGGQYHNWCNAFMGHMTREEIAGLRANTFFVSMSAIMGDTVFHQSAETV
ETKRAMFESAEKRFLLMDHTKFERRALYQFAHLREFDAVIVNQGTPVQVLRHLKDLGVNVVVAGMKVKAE

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=261, Percent_Identity=25.6704980842912, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI226510968, Length=247, Percent_Identity=28.3400809716599, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789829, Length=244, Percent_Identity=29.9180327868852, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790635, Length=247, Percent_Identity=26.3157894736842, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082344, Length=235, Percent_Identity=26.8085106382979, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1788069, Length=247, Percent_Identity=24.2914979757085, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789059, Length=255, Percent_Identity=25.8823529411765, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=25.5411255411255, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1787540, Length=241, Percent_Identity=23.6514522821577, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1787063, Length=209, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 35017; Mature: 34886

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRGGVFAPLYDILITRCQSRQYKPGSVMTQMSQDHSLNLFLAETLPGDSRQARQLARRQ
CCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHH
LIVEAVMAEGAIRIEEITERYGISLMTAHRDIDELAERGLLHKSRGVVSATSTSLVESSD
HHHHHHHHCCCCHHHHHHHHHCCEEEEHHCCHHHHHHCCCHHHCCCCEEECHHHHHHHHH
LYRATRQLEEKQAIAEVAVTYLEPGQAIFLDDSTTVFQMARYLPARTPLTVITNSLTLMN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ELKNIRDLTLLGLGGQYHNWCNAFMGHMTREEIAGLRANTFFVSMSAIMGDTVFHQSAET
HHHHHHHEEEEECCCHHHHHHHHHHHCCCHHHHCCCCHHHHEEEHHHHHHHHHHHCCHHH
VETKRAMFESAEKRFLLMDHTKFERRALYQFAHLREFDAVIVNQGTPVQVLRHLKDLGVN
HHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHCCCE
VVVAGMKVKAE
EEEECEEEECC
>Mature Secondary Structure 
TRGGVFAPLYDILITRCQSRQYKPGSVMTQMSQDHSLNLFLAETLPGDSRQARQLARRQ
CCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHH
LIVEAVMAEGAIRIEEITERYGISLMTAHRDIDELAERGLLHKSRGVVSATSTSLVESSD
HHHHHHHHCCCCHHHHHHHHHCCEEEEHHCCHHHHHHCCCHHHCCCCEEECHHHHHHHHH
LYRATRQLEEKQAIAEVAVTYLEPGQAIFLDDSTTVFQMARYLPARTPLTVITNSLTLMN
HHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHH
ELKNIRDLTLLGLGGQYHNWCNAFMGHMTREEIAGLRANTFFVSMSAIMGDTVFHQSAET
HHHHHHHEEEEECCCHHHHHHHHHHHCCCHHHHCCCCHHHHEEEHHHHHHHHHHHCCHHH
VETKRAMFESAEKRFLLMDHTKFERRALYQFAHLREFDAVIVNQGTPVQVLRHLKDLGVN
HHHHHHHHHHHHCEEEEECCCHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHHHHHCCCE
VVVAGMKVKAE
EEEECEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]