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The map label for this gene is ftsW [H]

Identifier: 218547546

GI number: 218547546

Start: 120372

End: 121616

Strand: Direct

Name: ftsW [H]

Synonym: EFER_0111

Alternate gene names: 218547546

Gene position: 120372-121616 (Clockwise)

Preceding gene: 218547545

Following gene: 218547547

Centisome position: 2.62

GC content: 51.97

Gene sequence:

>1245_bases
ATGCGTTTATCTCTCCCTCGCCTGAAAATGCCACGTCTGCCGGGATTCAGTATCCTTGCATGGCTCTTTACGGCAGTAAA
AGGCTGGGTGATGGGCTCGCGGGAAAAAGATACCGACAGCCTGATCATGTACGATCGTACTCTGCTGTGGCTGACCTTCG
GCCTTGCGGCGATCGGTTTTATCATGGTGACGTCGGCATCAATGCCGATCGGGCAACGCTTGACTAACGATCCCTTTTTC
TTCGCTAAGCGTGATGGCGTCTACCTGATCCTGGCGTTCATTCTGGCGATTATTACACTGCGCCTGCCGATGGAGTTCTG
GCAGCGCTATAGCACTACGATGCTGTTAGGTTCGATCATTTTGCTGATGATCGTACTGGTGGTAGGTAGCTCGGTAAAAG
GGGCATCGCGTTGGATCGATCTTGGTTTGCTGCGTATTCAGCCAGCGGAGCTGACTAAGTTATCGCTGTTTTGCTACATC
GCCAACTATCTGGTGCGTAAAGGCGACGAAGTACGTAATAACCTGCGTGGCTTCCTGAAACCGATGGGCGTGATTCTGGT
GTTGGCGATCTTGCTGCTGGCACAACCTGACCTCGGTACGGTGGTGGTGCTGTTTGTGACGACGCTGGCGATGCTGTTTT
TGGCGGGGGCGAAGCTGTGGCAGTTTATCGCCATTATCGGCATGGGAATCTCGGCTGTTATTCTGCTGATCCTCGCTGAA
CCGTACCGTATTCGCCGTGTAACTTCATTCTGGAATCCCTGGGATGATCCGTTTGGCAGCGGTTACCAACTGACACAATC
GCTGATGGCGTTTGGTCGTGGCGAATTATGGGGACAAGGGCTGGGTAATTCGGTGCAGAAACTGGAGTATCTGCCGGAGG
CGCATACTGACTTTATTTTCGCCATTATCGGTGAAGAACTGGGGTATGTCGGTGTGGTACTGGCACTTTTAATGGTATTC
TTCGTCGCTTTTCGCGCGATGTCTATCGGTCGTAAAGCGCTGGAAATTGATCACCGTTTTTCAGGCTTTTTGGCCTGTTC
TATCGGTATCTGGTTCAGCTTCCAGGCACTGGTGAACGTTGGCGCAGCCGCGGGGATGTTACCGACCAAAGGCCTGACAT
TGCCTCTCATCAGTTACGGCGGTTCGAGTTTATTGATTATGTCGACAGCGATCATGCTGTTGTTGCGCATTGATTATGAA
ACACGTCTGGAAAAAGCCCAGGCGTTTGCACGAGGTTCACGATGA

Upstream 100 bases:

>100_bases
ATATGGTTCTGCTCTCCCCGGCCTGTGCCAGCCTTGATCAGTTCAAGAACTTTGAACAACGAGGCAATGAATTTGCCCGT
CTGGCGAAGGAGTTAGGTTG

Downstream 100 bases:

>100_bases
GCGGTCAAGGGAAGCGGTTAATGGTGATGGCTGGTGGTACTGGTGGTCATGTGTTCCCAGGACTGGCGGTTGCGCACCAT
TTAATAGCCCAGGGGTGGGA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MRLSLPRLKMPRLPGFSILAWLFTAVKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFF
FAKRDGVYLILAFILAIITLRLPMEFWQRYSTTMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
ANYLVRKGDEVRNNLRGFLKPMGVILVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
PYRIRRVTSFWNPWDDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVF
FVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYE
TRLEKAQAFARGSR

Sequences:

>Translated_414_residues
MRLSLPRLKMPRLPGFSILAWLFTAVKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFF
FAKRDGVYLILAFILAIITLRLPMEFWQRYSTTMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
ANYLVRKGDEVRNNLRGFLKPMGVILVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
PYRIRRVTSFWNPWDDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVF
FVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYE
TRLEKAQAFARGSR
>Mature_414_residues
MRLSLPRLKMPRLPGFSILAWLFTAVKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFF
FAKRDGVYLILAFILAIITLRLPMEFWQRYSTTMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
ANYLVRKGDEVRNNLRGFLKPMGVILVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
PYRIRRVTSFWNPWDDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVF
FVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYE
TRLEKAQAFARGSR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=414, Percent_Identity=97.3429951690821, Blast_Score=791, Evalue=0.0,
Organism=Escherichia coli, GI1786853, Length=317, Percent_Identity=32.1766561514196, Blast_Score=158, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 46020; Mature: 46020

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLSLPRLKMPRLPGFSILAWLFTAVKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRLPMEFWQRYSTTMLLGSII
HHHHCCCCCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYIANYLVRKGDEVRNNLRGFLK
HHHHHHHHCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PMGVILVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
PYRIRRVTSFWNPWDDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIF
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCHHHHH
AIIGEELGYVGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYETRLEKAQAFARGSR
HHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRLSLPRLKMPRLPGFSILAWLFTAVKGWVMGSREKDTDSLIMYDRTLLWLTFGLAAIGF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
IMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRLPMEFWQRYSTTMLLGSII
HHHHCCCCCCCHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYIANYLVRKGDEVRNNLRGFLK
HHHHHHHHCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
PMGVILVLAILLLAQPDLGTVVVLFVTTLAMLFLAGAKLWQFIAIIGMGISAVILLILAE
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCC
PYRIRRVTSFWNPWDDPFGSGYQLTQSLMAFGRGELWGQGLGNSVQKLEYLPEAHTDFIF
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHCCCCHHHHHHHHCCCCCHHHHH
AIIGEELGYVGVVLALLMVFFVAFRAMSIGRKALEIDHRFSGFLACSIGIWFSFQALVNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAAAGMLPTKGLTLPLISYGGSSLLIMSTAIMLLLRIDYETRLEKAQAFARGSR
HHHCCCCCCCCCCEEHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]