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The map label for this gene is rbsK [H]

Identifier: 218547513

GI number: 218547513

Start: 80358

End: 81590

Strand: Direct

Name: rbsK [H]

Synonym: EFER_0074

Alternate gene names: 218547513

Gene position: 80358-81590 (Clockwise)

Preceding gene: 218547512

Following gene: 218547514

Centisome position: 1.75

GC content: 45.26

Gene sequence:

>1233_bases
ATGTATCGGGATACCCGTCGTGAACATATTGTCCGGCTACTTCGCAACAAGGAGGAGTGCACTGTCAGCGATTTAGCTCA
TTATTTTTCCGTTACCAAAGAGACTATTCGGACAGATTTAGCATGGTTGCAAAAGCGTGGCATGGTTATTCGCCATCATG
GTGGCGTCTCATTAAAAAAACATTTAATGCAAAACGCGCTTTCGCAACAAGAGTATGTCGATATGAGTTTGCTTATCAAG
CAACAACAGCAGGGAATTGGCTTTTTAACCTCCCTTGATGATAAAGGACACCGAATGGCAGGAAAAGTGTGTGTGTTAGG
ATCATTTAACGTCGATATCGTGGCGAAAGTGTATCGTTTTCCGCATGAAGGTGAAACGTTGGTGGCCAAAGAAACCACCA
TGGGGCCGGGAGGGAAAGGTGCGAATCAGGCACTTGCTGCTCATCGGGCTGGGGCGCAAATACACTTCGCCTGTAAGATT
GGTCGCGACCAGTTTAATCATTTTGCCCGCAATCATATTGAATCGATTGGTATTGGCTCATTTACTTTTTACGAATCTGA
ACGATCTACCACGGGTTGTGCAGTTATTTATGTAAATAATGAAGGTGAAAACATGATTGCCATGTCTCCAGGGGCTAATC
ATGAATTAAGTGATAACGATATTATTCAACTTTCTCACTTTATTGCTGAATCCAATGTCTTCATTGTGCAGATGGAGAAT
AATCTTGCCGCCACTCACCTGGCATTAAAATGTGCCAAACAAATGCAGGTGACAACGATTTTAAATCCTGCGCCGTGGTC
CATTGATGTTGCCACACTATTACCTTATGTTGATATTGTGACACCCAATGAAACCGAAGCATCGGCGATGTCAGGTATGG
TAATTAATGATATTTCTGATGCTATGAAGGCGGCGAAGCATATTCATAATGCCGGGCAGTGCTCAGTAATTATCACGATG
GGAAAACAAGGCGCATTAATTTATGACGGGCAACAATGTGCGCATATTCCGGCATTTTCGGCAGTCGCTGTAGATACAAC
AGGTGCGGGGGATGCGTTTAATGGCGCGCTCGCCGCCGCACTGGCGAAGGGTGAATCACTTGTTAAAGCAGCCTGGTATG
CCAGCGCTTTCGCTTCGCTGGCAGTAGAAAAAGAAGGGGCAGCCAATATGCCAGATATCTCTCTGGTGGATGCCAGAATT
CAGCAGCAGAACGTCGCCATTCAAACTTTCTGA

Upstream 100 bases:

>100_bases
AATAATATTTTTGTTTGTTTTTGTTTGTCTGTTTTTTTCTTGATAAAACTCCCGTTAATAATTTGTTTTTTAGTGATAAT
AAAATCAAAAAGGAAGACTT

Downstream 100 bases:

>100_bases
TGTTTCACTGAACGAAGGATGAAATATGAAAACAATTGAAGGGATTATTCCGGTAATGCTAACGCCTTTTACGGCGGATA
ATAAAATTGATTACTCTGGT

Product: transcriptional regulator of sugar metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MYRDTRREHIVRLLRNKEECTVSDLAHYFSVTKETIRTDLAWLQKRGMVIRHHGGVSLKKHLMQNALSQQEYVDMSLLIK
QQQQGIGFLTSLDDKGHRMAGKVCVLGSFNVDIVAKVYRFPHEGETLVAKETTMGPGGKGANQALAAHRAGAQIHFACKI
GRDQFNHFARNHIESIGIGSFTFYESERSTTGCAVIYVNNEGENMIAMSPGANHELSDNDIIQLSHFIAESNVFIVQMEN
NLAATHLALKCAKQMQVTTILNPAPWSIDVATLLPYVDIVTPNETEASAMSGMVINDISDAMKAAKHIHNAGQCSVIITM
GKQGALIYDGQQCAHIPAFSAVAVDTTGAGDAFNGALAAALAKGESLVKAAWYASAFASLAVEKEGAANMPDISLVDARI
QQQNVAIQTF

Sequences:

>Translated_410_residues
MYRDTRREHIVRLLRNKEECTVSDLAHYFSVTKETIRTDLAWLQKRGMVIRHHGGVSLKKHLMQNALSQQEYVDMSLLIK
QQQQGIGFLTSLDDKGHRMAGKVCVLGSFNVDIVAKVYRFPHEGETLVAKETTMGPGGKGANQALAAHRAGAQIHFACKI
GRDQFNHFARNHIESIGIGSFTFYESERSTTGCAVIYVNNEGENMIAMSPGANHELSDNDIIQLSHFIAESNVFIVQMEN
NLAATHLALKCAKQMQVTTILNPAPWSIDVATLLPYVDIVTPNETEASAMSGMVINDISDAMKAAKHIHNAGQCSVIITM
GKQGALIYDGQQCAHIPAFSAVAVDTTGAGDAFNGALAAALAKGESLVKAAWYASAFASLAVEKEGAANMPDISLVDARI
QQQNVAIQTF
>Mature_410_residues
MYRDTRREHIVRLLRNKEECTVSDLAHYFSVTKETIRTDLAWLQKRGMVIRHHGGVSLKKHLMQNALSQQEYVDMSLLIK
QQQQGIGFLTSLDDKGHRMAGKVCVLGSFNVDIVAKVYRFPHEGETLVAKETTMGPGGKGANQALAAHRAGAQIHFACKI
GRDQFNHFARNHIESIGIGSFTFYESERSTTGCAVIYVNNEGENMIAMSPGANHELSDNDIIQLSHFIAESNVFIVQMEN
NLAATHLALKCAKQMQVTTILNPAPWSIDVATLLPYVDIVTPNETEASAMSGMVINDISDAMKAAKHIHNAGQCSVIITM
GKQGALIYDGQQCAHIPAFSAVAVDTTGAGDAFNGALAAALAKGESLVKAAWYASAFASLAVEKEGAANMPDISLVDARI
QQQNVAIQTF

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=259, Percent_Identity=36.6795366795367, Blast_Score=155, Evalue=8e-38,
Organism=Escherichia coli, GI1790193, Length=307, Percent_Identity=38.4364820846906, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI87082343, Length=292, Percent_Identity=28.7671232876712, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI87081971, Length=297, Percent_Identity=25.9259259259259, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788417, Length=303, Percent_Identity=22.7722772277228, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788491, Length=310, Percent_Identity=23.2258064516129, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788017, Length=200, Percent_Identity=26.5, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789432, Length=161, Percent_Identity=30.4347826086957, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532905, Length=288, Percent_Identity=36.4583333333333, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6319884, Length=325, Percent_Identity=26.1538461538462, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI20128807, Length=270, Percent_Identity=37.037037037037, Blast_Score=135, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24583886, Length=271, Percent_Identity=30.2583025830258, Blast_Score=105, Evalue=4e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 44557; Mature: 44557

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS51000 HTH_DEOR_2 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRDTRREHIVRLLRNKEECTVSDLAHYFSVTKETIRTDLAWLQKRGMVIRHHGGVSLKK
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHH
HLMQNALSQQEYVDMSLLIKQQQQGIGFLTSLDDKGHRMAGKVCVLGSFNVDIVAKVYRF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEECCCHHHHHHHHHC
PHEGETLVAKETTMGPGGKGANQALAAHRAGAQIHFACKIGRDQFNHFARNHIESIGIGS
CCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCE
FTFYESERSTTGCAVIYVNNEGENMIAMSPGANHELSDNDIIQLSHFIAESNVFIVQMEN
EEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
NLAATHLALKCAKQMQVTTILNPAPWSIDVATLLPYVDIVTPNETEASAMSGMVINDISD
CCHHHHHHHHHHHHEEEEEEECCCCCCEEHHHHHCEEEEECCCCCHHHHHCCCHHHHHHH
AMKAAKHIHNAGQCSVIITMGKQGALIYDGQQCAHIPAFSAVAVDTTGAGDAFNGALAAA
HHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
LAKGESLVKAAWYASAFASLAVEKEGAANMPDISLVDARIQQQNVAIQTF
HHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCCEEEEEC
>Mature Secondary Structure
MYRDTRREHIVRLLRNKEECTVSDLAHYFSVTKETIRTDLAWLQKRGMVIRHHGGVSLKK
CCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHH
HLMQNALSQQEYVDMSLLIKQQQQGIGFLTSLDDKGHRMAGKVCVLGSFNVDIVAKVYRF
HHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEECCEEEEECCCHHHHHHHHHC
PHEGETLVAKETTMGPGGKGANQALAAHRAGAQIHFACKIGRDQFNHFARNHIESIGIGS
CCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHCCCCE
FTFYESERSTTGCAVIYVNNEGENMIAMSPGANHELSDNDIIQLSHFIAESNVFIVQMEN
EEEEECCCCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEEECC
NLAATHLALKCAKQMQVTTILNPAPWSIDVATLLPYVDIVTPNETEASAMSGMVINDISD
CCHHHHHHHHHHHHEEEEEEECCCCCCEEHHHHHCEEEEECCCCCHHHHHCCCHHHHHHH
AMKAAKHIHNAGQCSVIITMGKQGALIYDGQQCAHIPAFSAVAVDTTGAGDAFNGALAAA
HHHHHHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHH
LAKGESLVKAAWYASAFASLAVEKEGAANMPDISLVDARIQQQNVAIQTF
HHCCHHHHHHHHHHHHHHHHHEECCCCCCCCCCHHHHHHHHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]