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The map label for this gene is fixB [H]

Identifier: 218547489

GI number: 218547489

Start: 52358

End: 53299

Strand: Direct

Name: fixB [H]

Synonym: EFER_0050

Alternate gene names: 218547489

Gene position: 52358-53299 (Clockwise)

Preceding gene: 218547488

Following gene: 218547490

Centisome position: 1.14

GC content: 56.16

Gene sequence:

>942_bases
ATGAACACGTTTTCTCAAGTCTGGGTATTCAGCGATACCCCTTCTCGTCTGCCGGAACTGATGAACGGTGCGCAGGCTTT
AGCTAATCAAATCAACACATTTGTCCTCAATGATGCCGACGGCGCACTGGCAATCCAGTTTGGCGCTAATCATGTCTGGA
AATTAAGCGGCAAACCGGACGATCGGATGATCGAAGATTACGCCGGTGTCATGGCTGACACTATTCGCCAGCACGGCGCA
GACGGTCTGGTGCTGTTGCCGAATACCCGTCGCGGCAAATTACTGGCGGCAAAACTGGGTTATCGCCTTAAAGCGGCGGT
GTCTAACGATGCCAGCGCCGTTAGCGTGCAGGACGGTAAAGCGACAGTGAAACACATGGTTTACGGCGGTCTGGCGATTG
GCGAAGAACGCATTGCCACGCCGTATGCGGTACTGACCATCAGCAGCGGCACGTTTGATGCGGCTCAGCCAGACGCGTCA
CGTACTGGCGAAACACACACCGTGGCGTGGCAGGCTCCGGCGGTGGCGATTACCCGCACGGCAACGCAGGCGCGCCAGAG
CAACAGCGTCGATCTGGATAAAGCCCGTCTGGTGGTCAGCGTCGGTCGCGGCATTGGCAGCAAAGAAAACATTGCGCTGG
CAGAACAGCTTTGCAAGGCGATAGGTGCGGAGTTGGCCTGTTCTCGTCCGGTGGCGGAAAACGAAAAATGGATGGAGCAC
GAACGCTATGTCGGTATCTCCAACCTGATGCTGAAACCTGAACTGTACCTGGCGGTGGGGATCTCCGGGCAGATCCAGCA
CATGGTTGGCGCTAACGCATCGCAAACCATTTTCGCCATCAACAAAGATAAAAATGCGCCGATCTTCCAGTACGCGGATT
ACGGCATTGTTGGCGACGCCGTGAAGATCCTTCCGGCACTGACCGCAGCTTTTGCGCGTTGA

Upstream 100 bases:

>100_bases
AGCGCGAGCGTCAGCGCATCGTGATTGAAGGCGACGGCGAAGAACAGATCGCCGCATTTGCTGAAAATCTTCGCAAAGTC
ATTTAATTACAGGGGATGCT

Downstream 100 bases:

>100_bases
TCCACTCTGGCAGGGCTGCATTTTGGCCCTGCCGCTGACAGGGAGCTCTTATGTCCGAAGATATCTTTGACGCCATCATC
GTCGGTGCAGGGCTTGCCGG

Product: electron transfer flavoprotein FixB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPDDRMIEDYAGVMADTIRQHGA
DGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
RTGETHTVAWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAAFAR

Sequences:

>Translated_313_residues
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPDDRMIEDYAGVMADTIRQHGA
DGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
RTGETHTVAWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAAFAR
>Mature_313_residues
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPDDRMIEDYAGVMADTIRQHGA
DGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
RTGETHTVAWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDAVKILPALTAAFAR

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2025

COG function: function code C; Electron transfer flavoprotein, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF alpha-subunit/fixB family [H]

Homologues:

Organism=Homo sapiens, GI189181759, Length=222, Percent_Identity=36.4864864864865, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4503607, Length=222, Percent_Identity=36.4864864864865, Blast_Score=114, Evalue=1e-25,
Organism=Escherichia coli, GI1786226, Length=313, Percent_Identity=98.0830670926518, Blast_Score=632, Evalue=0.0,
Organism=Escherichia coli, GI1787990, Length=314, Percent_Identity=43.9490445859873, Blast_Score=277, Evalue=7e-76,
Organism=Escherichia coli, GI87082157, Length=116, Percent_Identity=38.7931034482759, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17506929, Length=225, Percent_Identity=32.8888888888889, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6325261, Length=142, Percent_Identity=36.6197183098592, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17136898, Length=192, Percent_Identity=38.0208333333333, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI24652801, Length=192, Percent_Identity=38.0208333333333, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001308
- InterPro:   IPR014730
- InterPro:   IPR014731
- InterPro:   IPR018206
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF; PF00766 ETF_alpha [H]

EC number: NA

Molecular weight: Translated: 33451; Mature: 33451

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00696 ETF_ALPHA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPD
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCEEEEECCCCC
DRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGK
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHCCEEEEEECCCCCEEEECCCH
ATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVAWQAPAVAITRT
HHHHHHHHCCEEECCHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEHH
ATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
HHHHHCCCCCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDA
HHCCCHHHEEECCCEEEEEECCCCCHHHHCCCCCCEEEEEECCCCCCEEEECCCCCHHHH
VKILPALTAAFAR
HHHHHHHHHHHCC
>Mature Secondary Structure
MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGALAIQFGANHVWKLSGKPD
CCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCEEEEECCCCC
DRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYRLKAAVSNDASAVSVQDGK
HHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEHHCCEEEEEECCCCCEEEECCCH
ATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDASRTGETHTVAWQAPAVAITRT
HHHHHHHHCCEEECCHHCCCCEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEEEHH
ATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLCKAIGAELACSRPVAENEKWMEH
HHHHHCCCCCCHHHHHEEEEECCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCHHHHHH
ERYVGISNLMLKPELYLAVGISGQIQHMVGANASQTIFAINKDKNAPIFQYADYGIVGDA
HHCCCHHHEEECCCEEEEEECCCCCHHHHCCCCCCEEEEEECCCCCCEEEECCCCCHHHH
VKILPALTAAFAR
HHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA