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The map label for this gene is fixA [H]

Identifier: 218547488

GI number: 218547488

Start: 51573

End: 52343

Strand: Direct

Name: fixA [H]

Synonym: EFER_0049

Alternate gene names: 218547488

Gene position: 51573-52343 (Clockwise)

Preceding gene: 218547481

Following gene: 218547489

Centisome position: 1.12

GC content: 50.97

Gene sequence:

>771_bases
ATGAAGATTATTACTTGCTATAAGTGCGTGCCTGATGAACAGGATATTGCGGTCAATAATGCTGATGGTTCATTAGACTT
CAGTAAAGCCGATGCCAAAATAAGCCAATACGATCTCAACGCTATTGAAGCGGCTTGTCAGTTAAAACAGCAGGCGGCAG
AAGCGCAGGTGACGGCCTTAAGTGTGGGCGGTAAAGCCCTGACCAACGCCAAAGGGCGTAAAGATGTGCTATCACGCGGT
CCGGATGAACTGATTGTGGTGATTGATGACCAGTTCGAGCAGGCACTGCCGCAACAAACGGCGACTGCACTGGCTGCAGC
CGCCCAGAAAGCAGGGTTTGATCTGATCCTCTGCGGCGATGGTTCTTCCGACCTTTATGCCCAACAGGTTGGTTTGCTGG
TGGGCGAAATCCTCGATATTCCAGTCGTTAACGGTGTCAGCAAAATTATTTCCCTGACGACAGATACCCTCACCGTTGAA
CGCGAACTGGAAGATGAAACAGAAACGTTAAGCATTCCGTTGCCTGCGGTTGTTGCTGTTTCCACTGATATCAACTCCCC
ACAAATTCCTTCGATGAAAGCCATTCTCGGCGCGGCGAAAAAGCCAGTCCAGGTATGGTCGGCGGCGGATATTGGCTTTA
ACGCCGTGGAAGCCTGGTCTGAACAACAGGTTGCCGCACCGAAACAGCGCGAGCGTCAGCGCATCGTGATTGAAGGCGAC
GGCGAAGAACAGATCGCCGCATTTGCTGAAAATCTTCGCAAAGTCATTTAA

Upstream 100 bases:

>100_bases
TATTGGTGATTAAAGTTTTATTCCCGAATTAAAGGACGTGATATCTGTAATTAACACCACCGATATGAACGACGTTTCCT
TCATGATTTCTGGAGATGCA

Downstream 100 bases:

>100_bases
TTACAGGGGATGCTATGAACACGTTTTCTCAAGTCTGGGTATTCAGCGATACCCCTTCTCGTCTGCCGGAACTGATGAAC
GGTGCGCAGGCTTTAGCTAA

Product: electron transfer flavoprotein FixA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVE
RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGD
GEEQIAAFAENLRKVI

Sequences:

>Translated_256_residues
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVE
RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGD
GEEQIAAFAENLRKVI
>Mature_256_residues
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRG
PDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVE
RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGD
GEEQIAAFAENLRKVI

Specific function: Required for anaerobic carnitine reduction. May bring reductant to CaiA [H]

COG id: COG2086

COG function: function code C; Electron transfer flavoprotein, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF beta-subunit/fixA family [H]

Homologues:

Organism=Homo sapiens, GI4503609, Length=192, Percent_Identity=32.2916666666667, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI62420877, Length=192, Percent_Identity=32.2916666666667, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI87081682, Length=256, Percent_Identity=97.65625, Blast_Score=472, Evalue=1e-134,
Organism=Escherichia coli, GI2367123, Length=257, Percent_Identity=55.6420233463035, Blast_Score=266, Evalue=7e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000049
- InterPro:   IPR014730
- InterPro:   IPR012255
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01012 ETF [H]

EC number: NA

Molecular weight: Translated: 27245; Mature: 27245

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS01065 ETF_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTAL
CCEEEEEECCCCCCCEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGD
ECCCHHHCCCCCHHHHHHCCCCEEEEEECCHHHHHCHHHHHHHHHHHHHHCCCEEEEECC
GSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVERELEDETETLSIPLPAVVAV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCEEECCCCEEEEE
STDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGD
ECCCCCCCCCHHHHHHHCCCCCHHHEEECCCCCHHHHHCCCHHHCCCCHHCCCEEEEECC
GEEQIAAFAENLRKVI
CHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEAACQLKQQAAEAQVTAL
CCEEEEEECCCCCCCEEEECCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEE
SVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTATALAAAAQKAGFDLILCGD
ECCCHHHCCCCCHHHHHHCCCCEEEEEECCHHHHHCHHHHHHHHHHHHHHCCCEEEEECC
GSSDLYAQQVGLLVGEILDIPVVNGVSKIISLTTDTLTVERELEDETETLSIPLPAVVAV
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEHHHCCCCCEEECCCCEEEEE
STDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVEAWSEQQVAAPKQRERQRIVIEGD
ECCCCCCCCCHHHHHHHCCCCCHHHEEECCCCCHHHHHCCCHHHCCCCHHCCCEEEEECC
GEEQIAAFAENLRKVI
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA