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The map label for this gene is yaaJ [H]

Identifier: 218547447

GI number: 218547447

Start: 6280

End: 7827

Strand: Reverse

Name: yaaJ [H]

Synonym: EFER_0006

Alternate gene names: 218547447

Gene position: 7827-6280 (Counterclockwise)

Preceding gene: 218547450

Following gene: 218547446

Centisome position: 0.17

GC content: 50.45

Gene sequence:

>1548_bases
ATGACGACCTCATGTATGATAGCGCCGATTAAGTCATGCCTCAGGGTATATACTGTTAATCAGTTGATAACGTTAACACA
GGATAGTTCTGGCGTACCGGCAGTAAGAGGGATGTTAATGCCTGATTTTTTCTCATTTATTAATAGTATTCTCTGGGGTT
CGGTCATGATCTACCTGCTCTTTGGGGCAGGTTGCTGGTTTACATGGCGTACCGGATTCGTTCAGTTTCGTTATATCCGC
CAGTTTGGCAAAAGTCTGAAAAATAGTCTTCATCCGCAATCCGGGGGCTTAACCGCTTTTCAGGCACTCTGTACCAGCCT
CGCTGCGCGCATAGGGAGTGGTAACCTTGCTGGCGTAGCGCTGGCGATCACCACTGGCGGCCCCGGCGCAATCTTTTGGA
TGTGGGTCGTTGCCTTCCTGGGAATGGCGACATCTTTTGCCGAGTGTTCTCTCGCACAACTCTATAAAGAGCGTGACCGT
AACGGGCAATTTCGTGGTGGCCCGGCATGGTATATGGCACGAGGCCTCGGGATGCGTTGGATGGGCGTGTTGTTTGCCGT
CTTTCTGTTGATTGCTTATGGGCTAATCATTAACGGTGTGCAGGCTAATTCGGTTTCCCGGGCGTTGCATTTTGCATTTG
ATTTCCCGCCTCTGATCAGCGGCGTGGCACTTGCAGTACTGATGCTGTTGGCTGTGTTGCGAGGGATACAAGGCGTAGCC
CGTCTGATGCAATGGTTTATACCCGTCGTGGCGTTGATCTGGATACTTGCCAGCGTGGTGATTTGCCTCATGAATATTGA
GCAGATTCCAGCGATCCTGTTAACGATTATTAAATGTGCATTCGGCTGGCAGGAAGCTGCCGGAGGCGTTGCGGGTTATA
CCCTAAGTCAGGCAATTACCAGTGGTTTCCAGCGTGGTATGTTTTCTAACGAAGCGGGTATGGGTTCTACACCAAATGCT
GCCGCCGCAGCTGCATCGTGGCCCCCCCACCCTGCTGCTCAGGGTATCGTGCAAATGATCGGCATTTTTATCGATACCCT
GGTAGTGTGTAGCGCAACAGCAATGCTGGTTTTGCTGGCAGGTCACGGTACGCCATTTGCGCCAATAGAAGGTATTCATC
TTGTGCAGAAAGCTATGACTGTACTGGTAGGTGAATGGGGCGCCAGTTTTGTAGCGATTATCGTGATCCTGTTTGCCTTC
AGCTCTATTGTCGCGAATTATATTTATGCAGAAAACAATCTCTATTTCTTGCATCTGGATAATCCAACTGCGATATGGGG
GCTGCGTATAGCAACCTGCTGCACAGTGATTTTAGGCACAGTGATGAGCTTTCCCTTAATGTGGCAGCTGACCGATATCA
TTATGGCCTGTATGGCGATCACTAACCTGACAGCAATTCTGCTGCTTTCCCCCGTGGTGCACACTATTGCCAGTGATTAT
CTGCGACAGCGCAAACTTGGTGTGCGTCCAACGTTCGATCCAATGCGCTACCCGGATATTGAACAGCAGCTCTCCCCGGA
CGCCTGGGATGAAGTACCACGAGAGTAA

Upstream 100 bases:

>100_bases
ATCACGACATCGTGACATCGCAACCGCAGACAATGCGCTGCACACTCCACGAAAGACATCAACTTTTCTGACTCGACGTT
GATATCACCCGCCTTTATGA

Downstream 100 bases:

>100_bases
TTGCAACTATCGATCAATTGATCCTGTTTTTTTGCTAAAGTCGCCTTAAATTTCCTGCAAGGACTGGATATGTTGATTCT
TATTTCACCTGCAAAAACTC

Product: amino acid sodium/proton transporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MTTSCMIAPIKSCLRVYTVNQLITLTQDSSGVPAVRGMLMPDFFSFINSILWGSVMIYLLFGAGCWFTWRTGFVQFRYIR
QFGKSLKNSLHPQSGGLTAFQALCTSLAARIGSGNLAGVALAITTGGPGAIFWMWVVAFLGMATSFAECSLAQLYKERDR
NGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGLIINGVQANSVSRALHFAFDFPPLISGVALAVLMLLAVLRGIQGVA
RLMQWFIPVVALIWILASVVICLMNIEQIPAILLTIIKCAFGWQEAAGGVAGYTLSQAITSGFQRGMFSNEAGMGSTPNA
AAAAASWPPHPAAQGIVQMIGIFIDTLVVCSATAMLVLLAGHGTPFAPIEGIHLVQKAMTVLVGEWGASFVAIIVILFAF
SSIVANYIYAENNLYFLHLDNPTAIWGLRIATCCTVILGTVMSFPLMWQLTDIIMACMAITNLTAILLLSPVVHTIASDY
LRQRKLGVRPTFDPMRYPDIEQQLSPDAWDEVPRE

Sequences:

>Translated_515_residues
MTTSCMIAPIKSCLRVYTVNQLITLTQDSSGVPAVRGMLMPDFFSFINSILWGSVMIYLLFGAGCWFTWRTGFVQFRYIR
QFGKSLKNSLHPQSGGLTAFQALCTSLAARIGSGNLAGVALAITTGGPGAIFWMWVVAFLGMATSFAECSLAQLYKERDR
NGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGLIINGVQANSVSRALHFAFDFPPLISGVALAVLMLLAVLRGIQGVA
RLMQWFIPVVALIWILASVVICLMNIEQIPAILLTIIKCAFGWQEAAGGVAGYTLSQAITSGFQRGMFSNEAGMGSTPNA
AAAAASWPPHPAAQGIVQMIGIFIDTLVVCSATAMLVLLAGHGTPFAPIEGIHLVQKAMTVLVGEWGASFVAIIVILFAF
SSIVANYIYAENNLYFLHLDNPTAIWGLRIATCCTVILGTVMSFPLMWQLTDIIMACMAITNLTAILLLSPVVHTIASDY
LRQRKLGVRPTFDPMRYPDIEQQLSPDAWDEVPRE
>Mature_514_residues
TTSCMIAPIKSCLRVYTVNQLITLTQDSSGVPAVRGMLMPDFFSFINSILWGSVMIYLLFGAGCWFTWRTGFVQFRYIRQ
FGKSLKNSLHPQSGGLTAFQALCTSLAARIGSGNLAGVALAITTGGPGAIFWMWVVAFLGMATSFAECSLAQLYKERDRN
GQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGLIINGVQANSVSRALHFAFDFPPLISGVALAVLMLLAVLRGIQGVAR
LMQWFIPVVALIWILASVVICLMNIEQIPAILLTIIKCAFGWQEAAGGVAGYTLSQAITSGFQRGMFSNEAGMGSTPNAA
AAAASWPPHPAAQGIVQMIGIFIDTLVVCSATAMLVLLAGHGTPFAPIEGIHLVQKAMTVLVGEWGASFVAIIVILFAFS
SIVANYIYAENNLYFLHLDNPTAIWGLRIATCCTVILGTVMSFPLMWQLTDIIMACMAITNLTAILLLSPVVHTIASDYL
RQRKLGVRPTFDPMRYPDIEQQLSPDAWDEVPRE

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=476, Percent_Identity=81.3025210084034, Blast_Score=772, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 55910; Mature: 55779

Theoretical pI: Translated: 8.34; Mature: 8.34

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHCCCCCCCCCCCCCCHHHHCCCCHHHCCCCC
>Mature Secondary Structure 
TTSCMIAPIKSCLRVYTVNQLITLTQDSSGVPAVRGMLMPDFFSFINSILWGSVMIYLL
CCCHHHHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGAGCWFTWRTGFVQFRYIRQFGKSLKNSLHPQSGGLTAFQALCTSLAARIGSGNLAGVA
HHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEE
LAITTGGPGAIFWMWVVAFLGMATSFAECSLAQLYKERDRNGQFRGGPAWYMARGLGMRW
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHH
MGVLFAVFLLIAYGLIINGVQANSVSRALHFAFDFPPLISGVALAVLMLLAVLRGIQGVA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLMQWFIPVVALIWILASVVICLMNIEQIPAILLTIIKCAFGWQEAAGGVAGYTLSQAIT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHH
SGFQRGMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVVCSATAMLVLLA
HHHHHCCCCCCCCCCCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GHGTPFAPIEGIHLVQKAMTVLVGEWGASFVAIIVILFAFSSIVANYIYAENNLYFLHLD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEC
NPTAIWGLRIATCCTVILGTVMSFPLMWQLTDIIMACMAITNLTAILLLSPVVHTIASDY
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRQRKLGVRPTFDPMRYPDIEQQLSPDAWDEVPRE
HHHHHCCCCCCCCCCCCCCHHHHCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]