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The map label for this gene is hisI [H]

Identifier: 218235744

GI number: 218235744

Start: 1405468

End: 1405773

Strand: Direct

Name: hisI [H]

Synonym: BCB4264_A1464

Alternate gene names: 218235744

Gene position: 1405468-1405773 (Clockwise)

Preceding gene: 218235029

Following gene: 218233645

Centisome position: 25.94

GC content: 34.64

Gene sequence:

>306_bases
ATGAAACCTAATTTTTCAAAAGGATTAATACCGGCAATTGTCATCGAAGAAGGTACGAAAGACGTTTTAATGCTAGCTTA
TATGAATGAAGAAGCATATGAAAAAACGTTAGAGACGAAAAGAACATGGTTTTATTCTCGTTCGAGGCAGTCGTTATGGA
ATAAGGGGGAAACATCAGGGAATGTTCAATATGTGCAATCTTTATATTTAGATTGTGATCAAGATTCAATTGTTGTGAAT
GTGAAACAAGTAGGACCTGCTTGTCATACGGGAGAGAAGACATGTTTTCACTATCAAATTATATAG

Upstream 100 bases:

>100_bases
CAGTTGATGCAGCGTTAGCGGCATCCATCTTTCATTATGGTGAGGCGACAGTGCATAGTGTAAAGCGAAAATTAAGAGAT
GCAAATATTGAGGTGCGGTT

Downstream 100 bases:

>100_bases
GGGGATACATATGGAAAATGCCTTTAAGTTGCTGTATAAAACAATTGAAGAACGAAAGGAAAGCCCACTTCCTGAATCGT
ATACAAATTATTTATTTTCA

Product: phosphoribosyl-AMP cyclohydrolase

Products: NA

Alternate protein names: PRA-CH [H]

Number of amino acids: Translated: 101; Mature: 101

Protein sequence:

>101_residues
MKPNFSKGLIPAIVIEEGTKDVLMLAYMNEEAYEKTLETKRTWFYSRSRQSLWNKGETSGNVQYVQSLYLDCDQDSIVVN
VKQVGPACHTGEKTCFHYQII

Sequences:

>Translated_101_residues
MKPNFSKGLIPAIVIEEGTKDVLMLAYMNEEAYEKTLETKRTWFYSRSRQSLWNKGETSGNVQYVQSLYLDCDQDSIVVN
VKQVGPACHTGEKTCFHYQII
>Mature_101_residues
MKPNFSKGLIPAIVIEEGTKDVLMLAYMNEEAYEKTLETKRTWFYSRSRQSLWNKGETSGNVQYVQSLYLDCDQDSIVVN
VKQVGPACHTGEKTCFHYQII

Specific function: Histidine biosynthesis; second step. Histidine biosynthesis; third step. [C]

COG id: COG0139

COG function: function code E; Phosphoribosyl-AMP cyclohydrolase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PRA-CH family [H]

Homologues:

Organism=Escherichia coli, GI2367128, Length=91, Percent_Identity=49.4505494505495, Blast_Score=101, Evalue=7e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002496
- ProDom:   PD002610 [H]

Pfam domain/function: PF01502 PRA-CH [H]

EC number: =3.5.4.19 [H]

Molecular weight: Translated: 11614; Mature: 11614

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNFSKGLIPAIVIEEGTKDVLMLAYMNEEAYEKTLETKRTWFYSRSRQSLWNKGETSG
CCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCC
NVQYVQSLYLDCDQDSIVVNVKQVGPACHTGEKTCFHYQII
CHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MKPNFSKGLIPAIVIEEGTKDVLMLAYMNEEAYEKTLETKRTWFYSRSRQSLWNKGETSG
CCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCHHHHHHCCCCCCC
NVQYVQSLYLDCDQDSIVVNVKQVGPACHTGEKTCFHYQII
CHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA