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The map label for this gene is mrdB [H]

Identifier: 218235664

GI number: 218235664

Start: 1046267

End: 1047523

Strand: Direct

Name: mrdB [H]

Synonym: BCB4264_A1073

Alternate gene names: 218235664

Gene position: 1046267-1047523 (Clockwise)

Preceding gene: 218232231

Following gene: 218235996

Centisome position: 19.31

GC content: 35.64

Gene sequence:

>1257_bases
TTGAACAAAAAAGGGGAGCGTTTTTTAAAAGAAGTTACGAACCATATTAAATCAAAAGAAGCGAAGGACTTAGTAGCAGC
TGAACTAAATTTTCACTTGAAACAGGCGAAGAATATGTGGATGGATAAAGGATTAAGTGAGGAAGTTGCTGAAGATAAGG
CTGTTGAACAAATGGGGAGTCCGATTAAACTTGGCCGGGAACTTAACAAACTTCATAAGCCAAAGGTGGATTGGTTCTTA
CTTATTTTATTAGTAGCTGCTATGGGGTTAGGGTTTTTACCAATAATCGCTCTTGGGCATACGAACGATTTACTAATGAA
CAAAGTAATTTTTGTAATTCTCGGCATTGCAACAGCTGTTGGGATGATGCTGCTTGATTACCGGAAGCTAGAAAGACTCG
GGTGGCTGTTTTATACAATTGGAATACTTATCTTGTTAGCTATAAAATGTTTTCCGACTGGTTACGTGATTGGGGAAGCG
ATAATAAAAATTGGCCCCATCAAAATTGACTGTTTAATGACGATACCATTCTTCTTTTTAGCTTGGGCTTCGTTTTTCAA
TAATAGTAGGTTAAAGTTTATACATCTTCTCATGTTGTACGTATTTTCTTTATATTTATTTTCAACTATATCAATTCTTT
TACCCATTTTCATCTACATTACGATGGTATTTGTTATGCTTTGGTGGAGTAAGTTAGGAAAGAAAACGGCATGGCTCATT
ACAATTTTACCAATTTTACCCTTTATTGTTAGGGATCTATTTTCCTGGTCTGCGGTAAAAGAATACCGGATAGCTAGAAT
TTTAGGATTTATAAATCCAGCGCATGATCAATGGGATTTACGTTTACAAGAGGCAATGTCTTCAGCGGGTTGGTTTGGTA
CATATGGAAATATAAAGTCTATCCGTGCTGCCCATACTGATTTTGTATTTGCAAGTTTGACTTACTATTATGGATATGTA
CTTGCGCTAGTTCTTGTCGTGATTCTTTCTCTTTTTGCAGTAAGAATAATGAACATAGCTTATAAAATAAATGATGGTTA
TGGTAAATTGCTTCTCGTTGGCGGAGTGACTCTTTTTGTAATCCATTTTATTTGTAACGTTGGCATGACCCTCGGGATAT
TACCACGTGTTTCTATATCATTACCTTTTATTAGCTACGGATTGATACCAACTCTGTTTCATGCATTTATAATGGGAATC
GTACTAAGTGTATATCGACGTAAAGATATGTCGTTTAGAATGAGAAAAACACCTTGA

Upstream 100 bases:

>100_bases
CAATTAAATGATAAAGGAAACAAGATGCTGCGAAAGGCAGAGAAGAATGCTACGAAGGCACGATTTATATTAAAAGGCTT
AGTACAGGAGTGAGAAAAAA

Downstream 100 bases:

>100_bases
TACTTATTATAAGTTGTATATAAAAGAATTCATTATTATGATCAAGTAAAAACGTAAATAGATAGTAGAAGAGGGGTATG
ATAAATACTCCTCTTTTCGT

Product: cell division protein, FtsW/RodA/SpoVE family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MNKKGERFLKEVTNHIKSKEAKDLVAAELNFHLKQAKNMWMDKGLSEEVAEDKAVEQMGSPIKLGRELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKVIFVILGIATAVGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWASFFNNSRLKFIHLLMLYVFSLYLFSTISILLPIFIYITMVFVMLWWSKLGKKTAWLI
TILPILPFIVRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIRAAHTDFVFASLTYYYGYV
LALVLVVILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFVIHFICNVGMTLGILPRVSISLPFISYGLIPTLFHAFIMGI
VLSVYRRKDMSFRMRKTP

Sequences:

>Translated_418_residues
MNKKGERFLKEVTNHIKSKEAKDLVAAELNFHLKQAKNMWMDKGLSEEVAEDKAVEQMGSPIKLGRELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKVIFVILGIATAVGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWASFFNNSRLKFIHLLMLYVFSLYLFSTISILLPIFIYITMVFVMLWWSKLGKKTAWLI
TILPILPFIVRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIRAAHTDFVFASLTYYYGYV
LALVLVVILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFVIHFICNVGMTLGILPRVSISLPFISYGLIPTLFHAFIMGI
VLSVYRRKDMSFRMRKTP
>Mature_418_residues
MNKKGERFLKEVTNHIKSKEAKDLVAAELNFHLKQAKNMWMDKGLSEEVAEDKAVEQMGSPIKLGRELNKLHKPKVDWFL
LILLVAAMGLGFLPIIALGHTNDLLMNKVIFVILGIATAVGMMLLDYRKLERLGWLFYTIGILILLAIKCFPTGYVIGEA
IIKIGPIKIDCLMTIPFFFLAWASFFNNSRLKFIHLLMLYVFSLYLFSTISILLPIFIYITMVFVMLWWSKLGKKTAWLI
TILPILPFIVRDLFSWSAVKEYRIARILGFINPAHDQWDLRLQEAMSSAGWFGTYGNIKSIRAAHTDFVFASLTYYYGYV
LALVLVVILSLFAVRIMNIAYKINDGYGKLLLVGGVTLFVIHFICNVGMTLGILPRVSISLPFISYGLIPTLFHAFIMGI
VLSVYRRKDMSFRMRKTP

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=342, Percent_Identity=23.6842105263158, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786277, Length=171, Percent_Identity=30.4093567251462, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 47691; Mature: 47691

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHCCHHHHHHCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]