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The map label for this gene is gmhB [H]

Identifier: 218235396

GI number: 218235396

Start: 2114493

End: 2115020

Strand: Reverse

Name: gmhB [H]

Synonym: BCB4264_A2210

Alternate gene names: 218235396

Gene position: 2115020-2114493 (Counterclockwise)

Preceding gene: 218234526

Following gene: 218233233

Centisome position: 39.03

GC content: 37.12

Gene sequence:

>528_bases
ATGACAAACATTAAAGCAATTTTCATTGATCGTGACGGTACAATTGGTGGTGACACTACAATACATTATCCAGGATCCTT
TACATTATTTCCATTCACAAAAACATCCTTGCAAAAACTAAAAGCTAAAAATATAAAAATTTTCTCTTTCACAAATCAAC
CCGGTATCGCAGATGGAATAGCAACTGTAGCCGATTTTGTACAAGAATTAGAAGGCTTCGGTTTTGATGATATTTATGTA
TGTCCTCATAAACACGGTGATGGTTGTGAATGCCGTAAACCAAGTACAGGCATGCTGCTTAAAGCAGCAAAAAAACATGG
ACTTAATTTAACACAATGTGCTGTAGTTGGTGATCGTTGGACTGATATTGTTGCAGGAGCAAAAGTAAATGCGACTACGA
TTCTAGTCCGAACAGGCGCTGGGTATGATGCTTTGCATACGTACCGAGACAAATGGGCACATATTGAACCAAACTACATT
GCAGATAACTTTGAAGATGCAACAAACTGGGTTTTAAATCAACTATAA

Upstream 100 bases:

>100_bases
AGAAGCTCATCCTTTTTACAAAAAATTAGGTTATGAAGTAAATGGCTACCGATTTGTAAAATATTTTTAAACTACTTTAT
AAAGTGAAGGGACTATAACT

Downstream 100 bases:

>100_bases
TACAAATGAAAATTTTGATTCACCCGAAATAATTTAAAACATAGTTAAAATAGCCTTTTTGGCAAATAATTGTATTCCAC
AAAACAGATCACCTCAAAAG

Product: hypothetical protein

Products: L-histidinol; phosphate

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MTNIKAIFIDRDGTIGGDTTIHYPGSFTLFPFTKTSLQKLKAKNIKIFSFTNQPGIADGIATVADFVQELEGFGFDDIYV
CPHKHGDGCECRKPSTGMLLKAAKKHGLNLTQCAVVGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYI
ADNFEDATNWVLNQL

Sequences:

>Translated_175_residues
MTNIKAIFIDRDGTIGGDTTIHYPGSFTLFPFTKTSLQKLKAKNIKIFSFTNQPGIADGIATVADFVQELEGFGFDDIYV
CPHKHGDGCECRKPSTGMLLKAAKKHGLNLTQCAVVGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYI
ADNFEDATNWVLNQL
>Mature_174_residues
TNIKAIFIDRDGTIGGDTTIHYPGSFTLFPFTKTSLQKLKAKNIKIFSFTNQPGIADGIATVADFVQELEGFGFDDIYVC
PHKHGDGCECRKPSTGMLLKAAKKHGLNLTQCAVVGDRWTDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIA
DNFEDATNWVLNQL

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=192, Percent_Identity=32.8125, Blast_Score=82, Evalue=2e-17,
Organism=Escherichia coli, GI87082027, Length=181, Percent_Identity=28.1767955801105, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.3.15

Molecular weight: Translated: 19268; Mature: 19137

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNIKAIFIDRDGTIGGDTTIHYPGSFTLFPFTKTSLQKLKAKNIKIFSFTNQPGIADGI
CCCEEEEEEECCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCCEEEEEECCCCCCHHHH
ATVADFVQELEGFGFDDIYVCPHKHGDGCECRKPSTGMLLKAAKKHGLNLTQCAVVGDRW
HHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEHEEEECCCH
TDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIADNFEDATNWVLNQL
HHHHCCCEECEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TNIKAIFIDRDGTIGGDTTIHYPGSFTLFPFTKTSLQKLKAKNIKIFSFTNQPGIADGI
CCEEEEEEECCCCCCCCCEEEECCCEEEEECCHHHHHHHHHCCEEEEEECCCCCCHHHH
ATVADFVQELEGFGFDDIYVCPHKHGDGCECRKPSTGMLLKAAKKHGLNLTQCAVVGDRW
HHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEHEEEECCCH
TDIVAGAKVNATTILVRTGAGYDALHTYRDKWAHIEPNYIADNFEDATNWVLNQL
HHHHCCCEECEEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-histidinol phosphate; H2O

Specific reaction: L-histidinol phosphate + H2O = L-histidinol + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]