Click here to switch to the map view.

The map label for this gene is vanYB [H]

Identifier: 218235210

GI number: 218235210

Start: 3180964

End: 3181695

Strand: Reverse

Name: vanYB [H]

Synonym: BCB4264_A3298

Alternate gene names: 218235210

Gene position: 3181695-3180964 (Counterclockwise)

Preceding gene: 218234803

Following gene: 218233222

Centisome position: 58.71

GC content: 33.61

Gene sequence:

>732_bases
TTGGTATTAGCAATGGGATGGAGTCTTGCTGCTTGTAGTGGAAAGCAAACATCTCAGGCAACTACTAATAATAACGATAA
AAATAAAAATGAAATACATGCGAAGAAAAAAGATGTTTTACCTATCTCTGATGTTAATGATTGGAGAATTATCCTTGTAA
ATAGAGAGCATATGTTATCAAAGGAACTAGGAATCGAATTAACAAGTATCACCCAAAATGCGAAGCCAAATATGAAAATA
GATAGTAGAATTGCAACTTCCTATCAGGATATGGTAGCAGCTGCAAAAAAAGAGGGAATCAATCTTTATTTAAGATCAGG
TTATCGAGCTATAAAATTACAACAAACGTATTATGATGCTTCAGTTAAAAGCTATAAATCTCAAGGCTTGTCGGATAAAG
AGGCTAGTGCTAAGGCATTGGAATATCTTCAGTATCCTGGTGCAAGTGAACATCATACTGGATTAGCGTTAGACATTATT
TCAGTTGAATGGCAGAATACTGTAGAAGATTTAAATGCAAAATTTGAAACTACCGATGCATTCAAATGGTTAGATAAGAA
TGCTGCAGAATATGGATTTACTCTCCGCTATCCAAAAGATAAAGAGAATATTACTGGCATTAAGTATGAGCCATGGCACT
ATCGTTATGTAGGGAAAGAAGTTGCTGTTTATCTAAAAGAAAAAGGGTTAACTTTAGAAGAATATAACGAAAAAATTAAG
TCTGGTAAGTAA

Upstream 100 bases:

>100_bases
GGATTTCAAGGAGATTCCTAGAGACGTGTTGGGAAATTGGTATAAAGACTAATAAACAAAAAGGGAATGAGATACAATTA
AAAAATTTATAATTTTAGCA

Downstream 100 bases:

>100_bases
AAATATGCTTTAATTTTATTAAACATTATGCACTGCTACAGGAAAAGGTGAATCTGAGGATGTGTTAACCTTCCGCCTAG
TATTGTAAAAACTGAGTATG

Product: D-alanyl-D-alanine carboxypeptidase

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MVLAMGWSLAACSGKQTSQATTNNNDKNKNEIHAKKKDVLPISDVNDWRIILVNREHMLSKELGIELTSITQNAKPNMKI
DSRIATSYQDMVAAAKKEGINLYLRSGYRAIKLQQTYYDASVKSYKSQGLSDKEASAKALEYLQYPGASEHHTGLALDII
SVEWQNTVEDLNAKFETTDAFKWLDKNAAEYGFTLRYPKDKENITGIKYEPWHYRYVGKEVAVYLKEKGLTLEEYNEKIK
SGK

Sequences:

>Translated_243_residues
MVLAMGWSLAACSGKQTSQATTNNNDKNKNEIHAKKKDVLPISDVNDWRIILVNREHMLSKELGIELTSITQNAKPNMKI
DSRIATSYQDMVAAAKKEGINLYLRSGYRAIKLQQTYYDASVKSYKSQGLSDKEASAKALEYLQYPGASEHHTGLALDII
SVEWQNTVEDLNAKFETTDAFKWLDKNAAEYGFTLRYPKDKENITGIKYEPWHYRYVGKEVAVYLKEKGLTLEEYNEKIK
SGK
>Mature_243_residues
MVLAMGWSLAACSGKQTSQATTNNNDKNKNEIHAKKKDVLPISDVNDWRIILVNREHMLSKELGIELTSITQNAKPNMKI
DSRIATSYQDMVAAAKKEGINLYLRSGYRAIKLQQTYYDASVKSYKSQGLSDKEASAKALEYLQYPGASEHHTGLALDII
SVEWQNTVEDLNAKFETTDAFKWLDKNAAEYGFTLRYPKDKENITGIKYEPWHYRYVGKEVAVYLKEKGLTLEEYNEKIK
SGK

Specific function: Vancomycin-inducible, penicillin-resistant, DD- carboxypeptidase that hydrolyzes depsipeptide- and D-alanyl-D- alanine-containing peptidoglycan precursors. Insensitive to beta- lactams [H]

COG id: COG1876

COG function: function code M; D-alanyl-D-alanine carboxypeptidase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M15B family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009045
- InterPro:   IPR003709 [H]

Pfam domain/function: PF02557 VanY [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 27631; Mature: 27631

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLAMGWSLAACSGKQTSQATTNNNDKNKNEIHAKKKDVLPISDVNDWRIILVNREHMLS
CEEEECCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
KELGIELTSITQNAKPNMKIDSRIATSYQDMVAAAKKEGINLYLRSGYRAIKLQQTYYDA
HHHCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHHHHH
SVKSYKSQGLSDKEASAKALEYLQYPGASEHHTGLALDIISVEWQNTVEDLNAKFETTDA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHCCCCCCCHH
FKWLDKNAAEYGFTLRYPKDKENITGIKYEPWHYRYVGKEVAVYLKEKGLTLEEYNEKIK
HHHHHCCHHHCCEEEECCCCCCCCCCCEECCEEEEECCHHEEEEECCCCCCHHHHHHHHH
SGK
CCC
>Mature Secondary Structure
MVLAMGWSLAACSGKQTSQATTNNNDKNKNEIHAKKKDVLPISDVNDWRIILVNREHMLS
CEEEECCCEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCEEEEEECCHHHHH
KELGIELTSITQNAKPNMKIDSRIATSYQDMVAAAKKEGINLYLRSGYRAIKLQQTYYDA
HHHCCEEEEECCCCCCCCEEHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEEEHHHHHH
SVKSYKSQGLSDKEASAKALEYLQYPGASEHHTGLALDIISVEWQNTVEDLNAKFETTDA
HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECHHHHHHHHCCCCCCCHH
FKWLDKNAAEYGFTLRYPKDKENITGIKYEPWHYRYVGKEVAVYLKEKGLTLEEYNEKIK
HHHHHCCHHHCCEEEECCCCCCCCCCCEECCEEEEECCHHEEEEECCCCCCHHHHHHHHH
SGK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8631706; 12663927 [H]