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The map label for this gene is cat1 [H]

Identifier: 218235205

GI number: 218235205

Start: 1770127

End: 1771641

Strand: Direct

Name: cat1 [H]

Synonym: BCB4264_A1863

Alternate gene names: 218235205

Gene position: 1770127-1771641 (Clockwise)

Preceding gene: 218233614

Following gene: 218234793

Centisome position: 32.66

GC content: 38.35

Gene sequence:

>1515_bases
ATGGAGAATAATTTAGATAGAATCAGAGATCAACGTCTAAAAGATCGGGTAGTTACACCTGAAGAAGCAGCCTCCTGGAT
TCAAAGTGGAATGACTTTAGGCTTAAGTGGGTTTACACGTGCAGGTGATGTAAAAGCAGTCCCATTTGCGCTTGTAAACC
GAGTTAAGAATGATGAATCTTTTAAAGTAAATGCTTATACTGGGGCTTCTTTAGGCTCGGATGTAGACAAATTATTTGCT
GAGGCAGGAATTTTAGGGAAAAGATTACCTTTCCAAGCTGACGCGACTATGCGAAAAGGAATTAATAACGGAGACTTTTT
ATTTGTGGATCAACACTTGTCTCATACAGCAGAGTTACTCCGCGCTGACGTTCTGGATATAGATTTCGCTATTTTGGAAG
CGGTTGCGATTACAGAGGACGGAATGATTATTCCAACCACTTCAATTGGAAATTCCTTAGCGTTTTCCTTAAATGCTAAG
TCTATTATTATTGAAATGAATATGGCTCAATCCGCGCAATTAGAGGGGCTACATGATCTATATGAACCAGGTAAACAAGG
GGAGAGGCTTCCAATTCCGCTTGTGAAAACAGATGACCGAATTGGAACAATCGGTATTCCAATTGATCCTGAAAAAGTAA
AGGGAATTGTGTTTACGAATCAATTGGATTCGCCATCGACAATTGTTCCTCCGGATGAAGAAACTGTTATTATGGCACAG
CATTTAATAGAATTCCTTCGAGAAGAAGTTAAAGTAGGCCGATTAACAAATCGTTTAGCGCCGTTACAATCAGGAATTGG
TTCAGTGGCTAACGCCGTATTGCATGGAATGTTAGATTCAGAATTTGAAGATTTAGAAGTATATTCCGAGGTTTTACAAG
ATGCAGTTTTTGATCTTATGGATGCTGGAAAAGTCAATTTTGCTTCTTGTTGTTCTATCACGCTTTCTGAAGAGAAAATG
CAACAAGTATTTTCTAACTTTGAAAAATATCGTGACAAATTAATGATGCGTCCGCAAGAGATTTCCAATCATCCTGAAAT
CATTCGTCGCCTTGGATTAATCTCAATTAATACTGCATTAGAATTAGATATATACGGAAATGTTAACTCTACTCACGTTT
TAGGTACAAAAATGATGAATGGTATTGGTGGGTCTGGTGATTTTGCAAGAAATGCACGCTTAGCTATCTTTGTTACTAAA
TCGATTGCGAAAGGTGGTAACATTTCAAGTATCGTTCCTTTCGTTTCTCATGTAGACCATACTGAACATGATGTAGATGT
TATCGTCACTGAACAGGGGTATGCCGACTTAAGGGGACTTGCGCCAAGAGAAAGAGTGGAACTTATTATTGAGAATTGCG
CACATCCAATGTATCGTGATCAACTACGTGCCTATTACGAAGAAGCAAAAACAAGAGGTGGACAAACTCCTCATATTTTA
GAAAAAGCTTTTTCTTGGCATACGAATTATGCTAAAAATGGAACAATGCTTGAAGCGGTAGTAGAAACTGTATAG

Upstream 100 bases:

>100_bases
CTGTTCTGTCTGAATTTTCGGCATTGTATACTAAAATCCCTATTTTGATAGTGTTAATGTGTAAAATAATTATGAATATT
CAATGAGAGAGGGATTACAT

Downstream 100 bases:

>100_bases
GTTTGTATCGTACGAAATAGTAAAATGAATGAGTGAGTTTGAAGATTAAATTTTAGAAAAAGAGAACGCCAACTTTTAGG
GATGGCGTTCTTTTTCTTTA

Product: acetyl-CoA hydrolase/transferase family protein

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIQSGMTLGLSGFTRAGDVKAVPFALVNRVKNDESFKVNAYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVLDIDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTDDRIGTIGIPIDPEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLREEVKVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QQVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEAVVETV

Sequences:

>Translated_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIQSGMTLGLSGFTRAGDVKAVPFALVNRVKNDESFKVNAYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVLDIDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTDDRIGTIGIPIDPEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLREEVKVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QQVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEAVVETV
>Mature_504_residues
MENNLDRIRDQRLKDRVVTPEEAASWIQSGMTLGLSGFTRAGDVKAVPFALVNRVKNDESFKVNAYTGASLGSDVDKLFA
EAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELLRADVLDIDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAK
SIIIEMNMAQSAQLEGLHDLYEPGKQGERLPIPLVKTDDRIGTIGIPIDPEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HLIEFLREEVKVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLMDAGKVNFASCCSITLSEEKM
QQVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTALELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTK
SIAKGGNISSIVPFVSHVDHTEHDVDVIVTEQGYADLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
EKAFSWHTNYAKNGTMLEAVVETV

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=486, Percent_Identity=42.5925925925926, Blast_Score=397, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17538151, Length=397, Percent_Identity=26.448362720403, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI32563853, Length=245, Percent_Identity=29.7959183673469, Blast_Score=76, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6319456, Length=510, Percent_Identity=42.5490196078431, Blast_Score=400, Evalue=1e-112,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 55629; Mature: 55629

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIQSGMTLGLSGFTRAGDVKAVPFALVNRVKNDES
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNAYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVLDIDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPLVKTDDRIGTIGIPIDPEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHCEEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLREEVKVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQQVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEAVVETV
HHHHHHCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MENNLDRIRDQRLKDRVVTPEEAASWIQSGMTLGLSGFTRAGDVKAVPFALVNRVKNDES
CCCCHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCCCCCCCCHHHHHHHHHHCCCCC
FKVNAYTGASLGSDVDKLFAEAGILGKRLPFQADATMRKGINNGDFLFVDQHLSHTAELL
EEEEEEECCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCEEEEEHHHHHHHHHH
RADVLDIDFAILEAVAITEDGMIIPTTSIGNSLAFSLNAKSIIIEMNMAQSAQLEGLHDL
HHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEECCCCHHHHCCHHHH
YEPGKQGERLPIPLVKTDDRIGTIGIPIDPEKVKGIVFTNQLDSPSTIVPPDEETVIMAQ
HCCCCCCCCCCCCEEECCCCEEEECCCCCHHHHCEEEEECCCCCCCCCCCCCCCHHHHHH
HLIEFLREEVKVGRLTNRLAPLQSGIGSVANAVLHGMLDSEFEDLEVYSEVLQDAVFDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DAGKVNFASCCSITLSEEKMQQVFSNFEKYRDKLMMRPQEISNHPEIIRRLGLISINTAL
HCCCCCHHHHEEEEECHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHCCEEECCEE
ELDIYGNVNSTHVLGTKMMNGIGGSGDFARNARLAIFVTKSIAKGGNISSIVPFVSHVDH
EEEEECCCCCCEEHHHHHHHCCCCCCCCCCCCEEEEEEEEHHCCCCCHHHHHHHHHHCCC
TEHDVDVIVTEQGYADLRGLAPRERVELIIENCAHPMYRDQLRAYYEEAKTRGGQTPHIL
CCCCEEEEEECCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHH
EKAFSWHTNYAKNGTMLEAVVETV
HHHHHHCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]