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The map label for this gene is 218235177

Identifier: 218235177

GI number: 218235177

Start: 1665934

End: 1667193

Strand: Direct

Name: 218235177

Synonym: BCB4264_A1755

Alternate gene names: NA

Gene position: 1665934-1667193 (Clockwise)

Preceding gene: 218231203

Following gene: 218234468

Centisome position: 30.74

GC content: 34.13

Gene sequence:

>1260_bases
ATGAGAGTGGAAGTATGGGGAGGAGCAGGAGAATACGGTCGCTCCTGCTACTTCGTAAAAAATAAAGAAACGAAAATAGT
ATTTGATTGTGGTATTAATCGATCTTATGAGGATAGTTATCCAAAAATAGAGAGAGAAGCTGTTCCATTTTTAGATGCGG
TATTTTTATCACATATTCATGAAGATCATACGATGGGTTTACCTTTATTAGCGAAGTATGGCTATAAGAAAAAAATTTGG
ACGACTCGTTATACGAAGGAGCAACTGCCGTTATATTATGAAAAATGGAGAAACTATAATGTGATGCAAGGGTGGAATTT
ACCTTATAGCGACCAACATATAAAAGATTTAAATTATGTATGTATTGATGAGATTAGTAATCCAAATGAATGGATACAAA
TTACTCCTACATTGCGGTTTCAATGGGGATATAGTGGGCATGTATTAGGAGCTGTTTGGTTTTTAGTTGATATGTGTAAT
ACATACGTATTTTATTCAGGCGACTATTCAGCAGATTCTAATATACTACGAGCTAATTTACCTGAGAAATTGGGCTACAA
TATAAAAATCGCAATTGTGGATGCCGCTTATCACACAGAGGATGTTTCGCAAAATGAACGTGTAAACGAACTATGTGCAG
AAATTGAACGAGTTATGCAAAATAAAGGAATAGCATTATTACCGCTTCCACAACTTGGTAGGGCGCAAGATATAGTATTG
TATTTATATGAACGATATAAAGAATTTCCGCTTATAGTAGATAAAGAAATTTTGGCTGGATTTGAAGAGATGTTCGTATA
TAAAGATTGGATAAAAAATAATGAAGAATTTAAATGGATTATGGAGAGTTTAAAAAGAAACATAATAGTGATGGATAATG
ACATTAGTATGCAAAATAGTTACGGAATAGTTGTAATGAGTGATGCGAATATGCAAACGAAACGAGCGCAGTTATATTAT
GAACAACTTCGGAATGAAAAGCGAAATGCCGTTATTTTTACTGGGCATATTGCGAAAGGGAGTTTTGCAGAAAAAGTTAT
GAAAGAACATGTAAGGAGTACATGTAGGGTGAAGCGAGTTGTGTATAAAGTTCACCAAAGTATAAGAGACGTTAAAGAGA
TGCTAAATACATTATTACCAGAACATACGGTGTTAGTGCACGCTTTGAAAGAGGATACGGATCGATTACAACAAAAGCTA
AGTACAGCAGGATATGAAAATGTATATTCACTTGCAATGGAACGTATAGAAGTCATTTAA

Upstream 100 bases:

>100_bases
TATCTATAGGCATGGCGATGGCCGTTGTTTCTGTTGGACTTACAACAATATGCTTATTACTGCTACAACATATGGAGCAA
AAACGAAAAGGGGTAGCATG

Downstream 100 bases:

>100_bases
AATGCAAAGGGGATAGGTATATGAAAAAAGTATTTGTATTCGTAAGCATTTTCTTTTGTTGTTTCCTTTATAACGTTAAG
GAAGGGTTTGCTGCTAGTCC

Product: metallo-beta-lactamase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRVEVWGGAGEYGRSCYFVKNKETKIVFDCGINRSYEDSYPKIEREAVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPLYYEKWRNYNVMQGWNLPYSDQHIKDLNYVCIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMCN
TYVFYSGDYSADSNILRANLPEKLGYNIKIAIVDAAYHTEDVSQNERVNELCAEIERVMQNKGIALLPLPQLGRAQDIVL
YLYERYKEFPLIVDKEILAGFEEMFVYKDWIKNNEEFKWIMESLKRNIIVMDNDISMQNSYGIVVMSDANMQTKRAQLYY
EQLRNEKRNAVIFTGHIAKGSFAEKVMKEHVRSTCRVKRVVYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQQKL
STAGYENVYSLAMERIEVI

Sequences:

>Translated_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKIVFDCGINRSYEDSYPKIEREAVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPLYYEKWRNYNVMQGWNLPYSDQHIKDLNYVCIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMCN
TYVFYSGDYSADSNILRANLPEKLGYNIKIAIVDAAYHTEDVSQNERVNELCAEIERVMQNKGIALLPLPQLGRAQDIVL
YLYERYKEFPLIVDKEILAGFEEMFVYKDWIKNNEEFKWIMESLKRNIIVMDNDISMQNSYGIVVMSDANMQTKRAQLYY
EQLRNEKRNAVIFTGHIAKGSFAEKVMKEHVRSTCRVKRVVYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQQKL
STAGYENVYSLAMERIEVI
>Mature_419_residues
MRVEVWGGAGEYGRSCYFVKNKETKIVFDCGINRSYEDSYPKIEREAVPFLDAVFLSHIHEDHTMGLPLLAKYGYKKKIW
TTRYTKEQLPLYYEKWRNYNVMQGWNLPYSDQHIKDLNYVCIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMCN
TYVFYSGDYSADSNILRANLPEKLGYNIKIAIVDAAYHTEDVSQNERVNELCAEIERVMQNKGIALLPLPQLGRAQDIVL
YLYERYKEFPLIVDKEILAGFEEMFVYKDWIKNNEEFKWIMESLKRNIIVMDNDISMQNSYGIVVMSDANMQTKRAQLYY
EQLRNEKRNAVIFTGHIAKGSFAEKVMKEHVRSTCRVKRVVYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQQKL
STAGYENVYSLAMERIEVI

Specific function: Unknown

COG id: COG1782

COG function: function code R; Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7706427, Length=431, Percent_Identity=26.9141531322506, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI33300633, Length=444, Percent_Identity=24.5495495495495, Blast_Score=115, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI32564696, Length=431, Percent_Identity=21.3457076566125, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI32566029, Length=432, Percent_Identity=22.6851851851852, Blast_Score=98, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6323307, Length=440, Percent_Identity=22.7272727272727, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24648013, Length=443, Percent_Identity=25.9593679458239, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI21358523, Length=437, Percent_Identity=23.1121281464531, Blast_Score=100, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022712
- InterPro:   IPR001279
- InterPro:   IPR004087
- InterPro:   IPR019975
- InterPro:   IPR004044
- InterPro:   IPR011108 [H]

Pfam domain/function: PF10996 Beta-Casp; PF07650 KH_2; PF00753 Lactamase_B; PF07521 RMMBL [H]

EC number: NA

Molecular weight: Translated: 49216; Mature: 49216

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKIVFDCGINRSYEDSYPKIEREAVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPLYYEKWRNYNVMQGWNLPYSDQHIKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHCCHHHHHHCCCCCEECCCCCCCCCHHCCCCEE
CIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMCNTYVFYSGDYSADSNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEECCC
PEKLGYNIKIAIVDAAYHTEDVSQNERVNELCAEIERVMQNKGIALLPLPQLGRAQDIVL
HHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YLYERYKEFPLIVDKEILAGFEEMFVYKDWIKNNEEFKWIMESLKRNIIVMDNDISMQNS
HHHHHHHCCCCEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCC
YGIVVMSDANMQTKRAQLYYEQLRNEKRNAVIFTGHIAKGSFAEKVMKEHVRSTCRVKRV
CCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQQKLSTAGYENVYSLAMERIEVI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVEVWGGAGEYGRSCYFVKNKETKIVFDCGINRSYEDSYPKIEREAVPFLDAVFLSHIH
CEEEEECCCCCCCCEEEEEECCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
EDHTMGLPLLAKYGYKKKIWTTRYTKEQLPLYYEKWRNYNVMQGWNLPYSDQHIKDLNYV
CCCCCCCHHHHHCCCCCCEEEECCCHHHCCHHHHHHCCCCCEECCCCCCCCCHHCCCCEE
CIDEISNPNEWIQITPTLRFQWGYSGHVLGAVWFLVDMCNTYVFYSGDYSADSNILRANL
EEECCCCCCCEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCEEEECCCCCCCCCEEECCC
PEKLGYNIKIAIVDAAYHTEDVSQNERVNELCAEIERVMQNKGIALLPLPQLGRAQDIVL
HHHHCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHH
YLYERYKEFPLIVDKEILAGFEEMFVYKDWIKNNEEFKWIMESLKRNIIVMDNDISMQNS
HHHHHHHCCCCEECHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCCC
YGIVVMSDANMQTKRAQLYYEQLRNEKRNAVIFTGHIAKGSFAEKVMKEHVRSTCRVKRV
CCEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
VYKVHQSIRDVKEMLNTLLPEHTVLVHALKEDTDRLQQKLSTAGYENVYSLAMERIEVI
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]