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The map label for this gene is perR [H]

Identifier: 218235160

GI number: 218235160

Start: 525012

End: 525440

Strand: Direct

Name: perR [H]

Synonym: BCB4264_A0542

Alternate gene names: 218235160

Gene position: 525012-525440 (Clockwise)

Preceding gene: 218236119

Following gene: 218232722

Centisome position: 9.69

GC content: 38.0

Gene sequence:

>429_bases
GTGGTCAAAGAAGAATTAAAAGAAGCGCTAGAAATGCTGAAAAATACGGGTGTACGCATTACTCCACAGCGTCATGCTAT
TTTAGAGTACCTTGTGGAATCAATGACGCACCCAACAGCGGATGATATTTATAAAGCATTAGAAGGTAAGTTTCCAAATA
TGAGTGTTGCAACTGTCTATAATAACTTACGTGTGTTTAAAGAGGTTGGACTTGTAAAGGAATTAACTTATGGAGACGCT
TCAAGTAGATTTGATTATGTTACAAGTCAACATTATCATGTGATTTGCGAAAAATGTGGTAAGATTGTTGATTTTCCTTA
TGGAGGCTTGGAAAAGCTGGAAGAGGAAGCTGCGAAAACGACAGGCTTCGTTATCAATAGTCATCGCTTAGAAATTTATG
GCGTTTGTCCAGAGTGTCATAAGGCGTAA

Upstream 100 bases:

>100_bases
ACATACTTATAGTAGAAATATTGACGATTTATAAGAAAAGGAGTACACTCTTTATAAGAATTATAAAATAATAATCCGTA
TAGAATCGGGGTGCATGACG

Downstream 100 bases:

>100_bases
TATATAATAAAGAAAGAGGCTGACGGCTATACGTCAGCCTCTTTCTTTATTATATAAGGATTAGCGTGAGGTTAATCGGG
ATTTACAGTGCTAAGTTAGT

Product: transcriptional regulator, Fur family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYGGLEKLEEEAAKTTGFVINSHRLEIYGVCPECHKA

Sequences:

>Translated_142_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYGGLEKLEEEAAKTTGFVINSHRLEIYGVCPECHKA
>Mature_142_residues
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVYNNLRVFKEVGLVKELTYGDA
SSRFDYVTSQHYHVICEKCGKIVDFPYGGLEKLEEEAAKTTGFVINSHRLEIYGVCPECHKA

Specific function: Hydrogen and organic peroxide sensor. Represses the expression of a regulon of peroxide-inducible genes such as katA, ahpC, ahpF, the heme biosynthesis operon (hemAXCDBL), fur, perR, zosA and mrgA [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=128, Percent_Identity=34.375, Blast_Score=76, Evalue=7e-16,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16117; Mature: 16117

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFKEVGLVKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYGGLEKLEEEAAKT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHH
TGFVINSHRLEIYGVCPECHKA
HCEEEECCCEEEEEECCHHCCC
>Mature Secondary Structure
MVKEELKEALEMLKNTGVRITPQRHAILEYLVESMTHPTADDIYKALEGKFPNMSVATVY
CCHHHHHHHHHHHHHCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCHHHHHH
NNLRVFKEVGLVKELTYGDASSRFDYVTSQHYHVICEKCGKIVDFPYGGLEKLEEEAAKT
HHHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHCCCEECCCCCCHHHHHHHHHHH
TGFVINSHRLEIYGVCPECHKA
HCEEEECCCEEEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202460; 9384377; 9701813; 12100544 [H]