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The map label for this gene is fes [H]

Identifier: 218235076

GI number: 218235076

Start: 2621728

End: 2622591

Strand: Reverse

Name: fes [H]

Synonym: BCB4264_A2712

Alternate gene names: 218235076

Gene position: 2622591-2621728 (Counterclockwise)

Preceding gene: 218232484

Following gene: 218232859

Centisome position: 48.4

GC content: 33.22

Gene sequence:

>864_bases
ATGAATGCATTTTTAACAAAGGAATTACTTCCGTGGATTCAATCTAAGTATCACGTTTATCAAGAAAGGAATCATACAAC
AATTGCTGGTTTCAGTCTTGGTGGCTTAGCAGCTTTTTATGCAGCACTTCAAAATCCACATGTTTTCGGAAATGTGTTGT
CAATGTCTGGATCCGTACATTGGAAAAAGGACGATTATGAAAATACAATTCCTTGGATTGAAAATCAAATTTCATTAATA
GATTCTAATGCAACTCACCTCAATACTTACATAGCAGTAGGTGAACTTGAAAACGAACCTCTTTTAACGGCTAATAGACG
GCTATATAAAGCTTTAGAAGAAATGAAACACCAAACCACTTACGAAGAGTTTCAAGGCGGACATGATAGCGTATGGTGGC
GAGAAAAGCTATTCGATGGATTAAGGGCATTAGAAAATAAAAAGGAGAGAGAATCTATGAATCAAGAAGAACTAGATAAA
AAACTAAAAAAACAAGAGATTTTAGTAAAAGATGAGAAAGTTTGGTCCTATACGTATGAAGATCATATTAGTTCTATCGT
TAAAGAAGCAGAAAAGAAAGGGTCTTTTGATCATTTACCTGGTAAAGGGAAACCTCTTAATCTTGATAAAGATCTTTCTT
ACAATCCTGAAAAGCAACTTTATAGAACTTTAGCAAATAATCATGTTTTACCTAGGTGGATTGAGCTTTCAAAAGAAATT
GACGATTTAAAAGAAAAGCTAAAAGAAAATACAAATACTGCAGAAGCAGCGGATTTAATTCGAACTATTAATAAAAAGGT
ATTAGAACATAATCTACTTTGTCCACCAAGCGCGCAAAAAATGAGGGTGAAAATGGATTTTTAA

Upstream 100 bases:

>100_bases
AACACTTAATTATTTAATTTACGGAAAAGAAATCCCATCGTGTATTGCTGTTGCTATAGATCCTGTTGATCGATTAGAAG
AGCTAACTTATAACGATAAA

Downstream 100 bases:

>100_bases
CGATATTCAGTTAAGCTATCGCTTACTATATAATTAAGTTAGGCATTTTCAATTCATTACTAAAAGGAGGCAAATATAGT
GAAGAATACGTATCAACTTC

Product: hypothetical protein

Products: Fe [C]

Alternate protein names: Ferric enterobactin esterase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNAFLTKELLPWIQSKYHVYQERNHTTIAGFSLGGLAAFYAALQNPHVFGNVLSMSGSVHWKKDDYENTIPWIENQISLI
DSNATHLNTYIAVGELENEPLLTANRRLYKALEEMKHQTTYEEFQGGHDSVWWREKLFDGLRALENKKERESMNQEELDK
KLKKQEILVKDEKVWSYTYEDHISSIVKEAEKKGSFDHLPGKGKPLNLDKDLSYNPEKQLYRTLANNHVLPRWIELSKEI
DDLKEKLKENTNTAEAADLIRTINKKVLEHNLLCPPSAQKMRVKMDF

Sequences:

>Translated_287_residues
MNAFLTKELLPWIQSKYHVYQERNHTTIAGFSLGGLAAFYAALQNPHVFGNVLSMSGSVHWKKDDYENTIPWIENQISLI
DSNATHLNTYIAVGELENEPLLTANRRLYKALEEMKHQTTYEEFQGGHDSVWWREKLFDGLRALENKKERESMNQEELDK
KLKKQEILVKDEKVWSYTYEDHISSIVKEAEKKGSFDHLPGKGKPLNLDKDLSYNPEKQLYRTLANNHVLPRWIELSKEI
DDLKEKLKENTNTAEAADLIRTINKKVLEHNLLCPPSAQKMRVKMDF
>Mature_287_residues
MNAFLTKELLPWIQSKYHVYQERNHTTIAGFSLGGLAAFYAALQNPHVFGNVLSMSGSVHWKKDDYENTIPWIENQISLI
DSNATHLNTYIAVGELENEPLLTANRRLYKALEEMKHQTTYEEFQGGHDSVWWREKLFDGLRALENKKERESMNQEELDK
KLKKQEILVKDEKVWSYTYEDHISSIVKEAEKKGSFDHLPGKGKPLNLDKDLSYNPEKQLYRTLANNHVLPRWIELSKEI
DDLKEKLKENTNTAEAADLIRTINKKVLEHNLLCPPSAQKMRVKMDF

Specific function: Upon internalization, ferric enterobactin is processed via an exquisitely specific pathway that is dependent on FES activity, making iron available for metabolic use [H]

COG id: COG2382

COG function: function code P; Enterochelin esterase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fes family [H]

Homologues:

Organism=Escherichia coli, GI1786799, Length=137, Percent_Identity=32.1167883211679, Blast_Score=72, Evalue=5e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR021764
- InterPro:   IPR000801
- InterPro:   IPR014756 [H]

Pfam domain/function: PF11806 DUF3327; PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 33428; Mature: 33428

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAFLTKELLPWIQSKYHVYQERNHTTIAGFSLGGLAAFYAALQNPHVFGNVLSMSGSVH
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCEE
WKKDDYENTIPWIENQISLIDSNATHLNTYIAVGELENEPLLTANRRLYKALEEMKHQTT
ECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
YEEFQGGHDSVWWREKLFDGLRALENKKERESMNQEELDKKLKKQEILVKDEKVWSYTYE
HHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHEECCHHHHHHHH
DHISSIVKEAEKKGSFDHLPGKGKPLNLDKDLSYNPEKQLYRTLANNHVLPRWIELSKEI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
DDLKEKLKENTNTAEAADLIRTINKKVLEHNLLCPPSAQKMRVKMDF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC
>Mature Secondary Structure
MNAFLTKELLPWIQSKYHVYQERNHTTIAGFSLGGLAAFYAALQNPHVFGNVLSMSGSVH
CCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHCCCHHHHHHHHCCCCEE
WKKDDYENTIPWIENQISLIDSNATHLNTYIAVGELENEPLLTANRRLYKALEEMKHQTT
ECCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHH
YEEFQGGHDSVWWREKLFDGLRALENKKERESMNQEELDKKLKKQEILVKDEKVWSYTYE
HHHHCCCCCCHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHEECCHHHHHHHH
DHISSIVKEAEKKGSFDHLPGKGKPLNLDKDLSYNPEKQLYRTLANNHVLPRWIELSKEI
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHH
DDLKEKLKENTNTAEAADLIRTINKKVLEHNLLCPPSAQKMRVKMDF
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ferrienterobactin [C]

Specific reaction: ferrienterobactin = Fe [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2974033; 9278503; 8905232 [H]