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The map label for this gene is murB [H]

Identifier: 218235044

GI number: 218235044

Start: 3931429

End: 3932334

Strand: Reverse

Name: murB [H]

Synonym: BCB4264_A4010

Alternate gene names: 218235044

Gene position: 3932334-3931429 (Counterclockwise)

Preceding gene: 218235761

Following gene: 218235806

Centisome position: 72.57

GC content: 38.41

Gene sequence:

>906_bases
ATGGAACAATTAGTAAATGAGCTTATAGAAGCAGACGTTGGTCGTGTTTTAGTTAACGAGCCGTTAGCACGTTATACAAC
TATGAAAATAGGTGGACCAGCGGATATTTTAATTGTGCCAAAGCATGTAGCCGGTATTGAAAAAACATTACAGTTAGTAA
AACAATACAAAACGAAGTGGATTGTAATTGGTCGCGGTTCAAACCTTCTTGTATCTGATCAAGGCATAGAAGGTGTTGTT
ATTCGTTTAGGAGAAGGATTAGATCACTTAGAGGTCGAAAAACATAAGGTAAGAGTTGGTAGTGGATATCCTCTTATTAA
ATTGTCAACTTTACTTAGTCGTCAAGGGTTAGCTGGATTGGAGTTTGCAAGCGGTATTCCAGGAAGTGTCGGTGGTGCAG
TATATATGAATGCAGGTGCACATAAATCGGATATATCGAGTGTATTATCGAAGGCTCTCATTCTGTTTGAAGACGGTACA
ATTGACTGGTTAACGAATAAAGAACTGGAGTTTTCTTATCGGGCATCTGTATTGCAAACGAAACGTCCTGGTATTGTTTT
AGAGGCGGTGTTTCAATTACAGGCGGGAAAACGTGAAGAAATTGTACGTAGCATGCAAAATAATAAAGATTACCGCCGTG
AAACGCAACCATGGAATCACCCGTGTGCAGGAAGTGTATTTCGGAATCCAATCCCACATTTTGCAGGAGATTTAGTAGAA
AAAGCAGGGCTTCGTGGTTATAGGATTGGTGGAGCTCAAATTTCTGAAATGCATGGCAATTTTATTGTTAATACTGGGGG
AGCTTCAGCGCAAGATGTATTGTCTTTAATTGAATTAATAAAACATACAATTAAGGATAAATTTGATGTAGATATGCACA
CAGAAGTAGAAATCATTGGAAGATAA

Upstream 100 bases:

>100_bases
TTGATTTAGGAGCTGTACTGCCCGTAAATAGAGGGATAACGTTAGGTGAACGCCCTGCATATTATTGTCATAAGGAGACT
TAATATGGGGGAGATTGTCT

Downstream 100 bases:

>100_bases
CGGTTATTCGTTCCGCTCATTATCATTTATGTTATAATAAGAAGATAAGAACGGCATGAGGAACATGCCGTTCTTTATGT
TACATAGGGGGATCGTACAT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase 1 [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKWIVIGRGSNLLVSDQGIEGVV
IRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGT
IDWLTNKELEFSYRASVLQTKRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVE
KAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIGR

Sequences:

>Translated_301_residues
MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKWIVIGRGSNLLVSDQGIEGVV
IRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGT
IDWLTNKELEFSYRASVLQTKRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVE
KAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIGR
>Mature_301_residues
MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKWIVIGRGSNLLVSDQGIEGVV
IRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGLEFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGT
IDWLTNKELEFSYRASVLQTKRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVE
KAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIGR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33027; Mature: 33027

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKW
CHHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCE
IVIGRGSNLLVSDQGIEGVVIRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGL
EEEECCCEEEEECCCCCEEEEEECCCCCCCEEEHHEEEECCCCCHHHHHHHHHHCCCCCC
EFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGTIDWLTNKELEFSYRASVLQT
HHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCEEEECCCCCCHHHHHHHHHC
KRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHH
KAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIG
HCCCCEEEECCCCHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEC
R
C
>Mature Secondary Structure
MEQLVNELIEADVGRVLVNEPLARYTTMKIGGPADILIVPKHVAGIEKTLQLVKQYKTKW
CHHHHHHHHHHHHHHHHHCCCHHHHEEEEECCCEEEEEECHHHHHHHHHHHHHHHHCCCE
IVIGRGSNLLVSDQGIEGVVIRLGEGLDHLEVEKHKVRVGSGYPLIKLSTLLSRQGLAGL
EEEECCCEEEEECCCCCEEEEEECCCCCCCEEEHHEEEECCCCCHHHHHHHHHHCCCCCC
EFASGIPGSVGGAVYMNAGAHKSDISSVLSKALILFEDGTIDWLTNKELEFSYRASVLQT
HHHCCCCCCCCCEEEEECCCCHHHHHHHHHHHEEEEECCCEEEECCCCCCHHHHHHHHHC
KRPGIVLEAVFQLQAGKREEIVRSMQNNKDYRRETQPWNHPCAGSVFRNPIPHFAGDLVE
CCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHH
KAGLRGYRIGGAQISEMHGNFIVNTGGASAQDVLSLIELIKHTIKDKFDVDMHTEVEIIG
HCCCCEEEECCCCHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12721630 [H]