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The map label for this gene is cysC [C]

Identifier: 218234957

GI number: 218234957

Start: 1416135

End: 1416728

Strand: Direct

Name: cysC [C]

Synonym: BCB4264_A1478

Alternate gene names: 218234957

Gene position: 1416135-1416728 (Clockwise)

Preceding gene: 218235386

Following gene: 218232883

Centisome position: 26.13

GC content: 37.04

Gene sequence:

>594_bases
ATGGATACGAATATTACTTGGCATACAGCTTCGGTTTCAAAAGATGAGAGAAGAGTGAAGAATGGACATCATAGTTTTGT
AATTTGGTTTACTGGTTTATCAGCTTCGGGTAAATCTACAGTAGCGAATGCGGTCGCTCGTAAACTGTTTGAAAAGAATA
TTGGAAATTATGTGCTGGATGGGGATAACATTCGCCACGGTTTAAATAAAGACTTAGGATTTTCTGAAAGTGATCGCATG
GAAAATATAAGACGTATTGGCGAAGTGGCAAAGTTATTTGTAGACCAAGGAGCAGTTGTCCTTACAGCATTTATTTCACC
ATTTCGAGTAGACCGCAAACAAGTAAGAGATTTATTAGCGGCAGATGAATTTATTGAAATTTTTGTGAAGTGTCCGATTG
AAGAGTGTGAGAAACGTGATCCGAAAGGACTTTATAAAAAGGCAAGAAAAGGTGATATTAAGGATTTCACAGGTATTGAT
TCGCCTTATGAAGAGCCAGAGCAAGCGGAATTAATTGTAGAAACGCACAAATATTCTATTGAAGAATGTGCAGAACAAAT
CGTGAAGTACTTACAAGAGCGTAGTTTTATATAG

Upstream 100 bases:

>100_bases
CGGTGAGATTCCGCCAAGTACATTTAGTCGTAAAGAAGTAGTGGAAGTGCTAATTAAAGGCTTGAAAAAAGAAGTAGTAA
CAGAATAGGGAGAGAACGAG

Downstream 100 bases:

>100_bases
GGGGATAAACAATGAGTTATGAAAAAGTATGGGCTAACAATGAAAAATTAAATCAGACCGAGAAAAATAAATTAGAAAAA
GATGGCTTAGAAATTTTTAA

Product: adenylylsulfate kinase

Products: NA

Alternate protein names: APS kinase; ATP adenosine-5'-phosphosulfate 3'-phosphotransferase; Adenosine-5'-phosphosulfate kinase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MDTNITWHTASVSKDERRVKNGHHSFVIWFTGLSASGKSTVANAVARKLFEKNIGNYVLDGDNIRHGLNKDLGFSESDRM
ENIRRIGEVAKLFVDQGAVVLTAFISPFRVDRKQVRDLLAADEFIEIFVKCPIEECEKRDPKGLYKKARKGDIKDFTGID
SPYEEPEQAELIVETHKYSIEECAEQIVKYLQERSFI

Sequences:

>Translated_197_residues
MDTNITWHTASVSKDERRVKNGHHSFVIWFTGLSASGKSTVANAVARKLFEKNIGNYVLDGDNIRHGLNKDLGFSESDRM
ENIRRIGEVAKLFVDQGAVVLTAFISPFRVDRKQVRDLLAADEFIEIFVKCPIEECEKRDPKGLYKKARKGDIKDFTGID
SPYEEPEQAELIVETHKYSIEECAEQIVKYLQERSFI
>Mature_197_residues
MDTNITWHTASVSKDERRVKNGHHSFVIWFTGLSASGKSTVANAVARKLFEKNIGNYVLDGDNIRHGLNKDLGFSESDRM
ENIRRIGEVAKLFVDQGAVVLTAFISPFRVDRKQVRDLLAADEFIEIFVKCPIEECEKRDPKGLYKKARKGDIKDFTGID
SPYEEPEQAELIVETHKYSIEECAEQIVKYLQERSFI

Specific function: Catalyzes the synthesis of activated sulfate [H]

COG id: COG0529

COG function: function code P; Adenylylsulfate kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the APS kinase family [H]

Homologues:

Organism=Homo sapiens, GI46094058, Length=201, Percent_Identity=49.7512437810945, Blast_Score=202, Evalue=2e-52,
Organism=Homo sapiens, GI34447231, Length=201, Percent_Identity=48.2587064676617, Blast_Score=196, Evalue=1e-50,
Organism=Homo sapiens, GI62912492, Length=201, Percent_Identity=48.2587064676617, Blast_Score=196, Evalue=1e-50,
Organism=Escherichia coli, GI1789107, Length=196, Percent_Identity=51.530612244898, Blast_Score=219, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI17542422, Length=201, Percent_Identity=49.2537313432836, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6322852, Length=193, Percent_Identity=58.5492227979275, Blast_Score=225, Evalue=4e-60,
Organism=Drosophila melanogaster, GI24667032, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24667028, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI24667036, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=4e-48,
Organism=Drosophila melanogaster, GI116007838, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667044, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24667040, Length=202, Percent_Identity=48.019801980198, Blast_Score=187, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002891 [H]

Pfam domain/function: PF01583 APS_kinase [H]

EC number: =2.7.1.25 [H]

Molecular weight: Translated: 22514; Mature: 22514

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTNITWHTASVSKDERRVKNGHHSFVIWFTGLSASGKSTVANAVARKLFEKNIGNYVLD
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEC
GDNIRHGLNKDLGFSESDRMENIRRIGEVAKLFVDQGAVVLTAFISPFRVDRKQVRDLLA
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
ADEFIEIFVKCPIEECEKRDPKGLYKKARKGDIKDFTGIDSPYEEPEQAELIVETHKYSI
HHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHCCH
EECAEQIVKYLQERSFI
HHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDTNITWHTASVSKDERRVKNGHHSFVIWFTGLSASGKSTVANAVARKLFEKNIGNYVLD
CCCCEEEEECCCCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCEEEC
GDNIRHGLNKDLGFSESDRMENIRRIGEVAKLFVDQGAVVLTAFISPFRVDRKQVRDLLA
CCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHH
ADEFIEIFVKCPIEECEKRDPKGLYKKARKGDIKDFTGIDSPYEEPEQAELIVETHKYSI
HHHHHHHHHHCCHHHHHCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHCCH
EECAEQIVKYLQERSFI
HHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]