Click here to switch to the map view.

The map label for this gene is des [H]

Identifier: 218234936

GI number: 218234936

Start: 2874061

End: 2875092

Strand: Reverse

Name: des [H]

Synonym: BCB4264_A3000

Alternate gene names: 218234936

Gene position: 2875092-2874061 (Counterclockwise)

Preceding gene: 218230864

Following gene: 218233947

Centisome position: 53.06

GC content: 34.5

Gene sequence:

>1032_bases
ATGACCTTAGAAAATACTAAAAATTTAAAAAAACAAGTTGCTCCTTTTGAAAAATCAACGATTAAAAAAAGTGTTTGGCA
ACTGATCAACACAATCGTGCCATTTATTATTTTATGGTACCTTGCTTATAAAAGTTTGTCAGTTTCTTATTGGTTAACAT
TAGTTCCAGCACTGTTAGCCGCTGGATTTATGACAAGAATTTTCATTATTTTTCATGATTGCACCCATTATTCGTTCTTT
AAAAGTCGACGTGCAAATAGAATAGTTGGAACGTGTATGGGTGTTTTAACATTATTCCCATTTGATCAGTGGGGGCATGA
ACATTCTATTCACCACGCTACAAGTGGTAATTTGGATAAGAGGGGTACAGGGGATATTTGGACGCTTACAGTTGATGAAT
ATGTAGCTGCACCATTTAGACTTCGTTTAGCATATCGCTTATATCGCAATCCATTCGTTATGTTTGGATTAGGTCCGATT
TATGTTTTCTTGCTTAAAAATAGATTTAACCGAAAAGGTGCAAGGCAGAAAGAACGTATGAATACTTATTTGACGAATAT
TATAATTGTTGCTGTAGTAGCTATACTTTGCTGGGCAATTGGGTGGCAATCGTTTCTGTTAGTACATGGTACTATATTCT
TAATAGCAGGTTCAGTAGGGATTTGGCTGTTTTACGTACAGCACACATTTGAGGATTCTTATTTTGAAGAGGATAAAGAT
TGGGAATATGTGAAAGCGGCAGTGGAAGGAAGTTCTTTTTATAAGCTTCCTAAAATTTTGCAATTCTTAACTGGTAATAT
TGGATTCCATCATGTTCACCATTTAAGCCCAAGGGTACCTAACTATAAACTAGAAGAGGCACACAATAATACGCTTCCGT
TAAAAAATGTACCAACGATTACGCTTGCTACAAGCTTACAATCACTACGTTTCCGTCTTTGGGATGAGAAAAGTAACAAT
TTTGTTAGCTTTAAAGATGTCAAAAATATAATTAAAAATAATGTTTCTGTTCGAGTGAAATCTGAACTATAA

Upstream 100 bases:

>100_bases
TTTTCATAGTATATAATATTTATTATAGCTACTTTTAACACCTGATACTAATAGTGTGCTATAATATGAATTAGCAACAA
AAAGGAAAGGAATTAGAACA

Downstream 100 bases:

>100_bases
TTGCATCGTATATAAAACTCCCCTTAATCATTTTCGATTTAAGGGGAGTTTGTGTTTAAAGAGTAGATGCCAGATAAGAG
GAAAATTTACATAATTCAAA

Product: fatty acid desaturase

Products: NA

Alternate protein names: Delta(5) acyl-lipid desaturase; Delta(5) desaturase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MTLENTKNLKKQVAPFEKSTIKKSVWQLINTIVPFIILWYLAYKSLSVSYWLTLVPALLAAGFMTRIFIIFHDCTHYSFF
KSRRANRIVGTCMGVLTLFPFDQWGHEHSIHHATSGNLDKRGTGDIWTLTVDEYVAAPFRLRLAYRLYRNPFVMFGLGPI
YVFLLKNRFNRKGARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKD
WEYVKAAVEGSSFYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLQSLRFRLWDEKSNN
FVSFKDVKNIIKNNVSVRVKSEL

Sequences:

>Translated_343_residues
MTLENTKNLKKQVAPFEKSTIKKSVWQLINTIVPFIILWYLAYKSLSVSYWLTLVPALLAAGFMTRIFIIFHDCTHYSFF
KSRRANRIVGTCMGVLTLFPFDQWGHEHSIHHATSGNLDKRGTGDIWTLTVDEYVAAPFRLRLAYRLYRNPFVMFGLGPI
YVFLLKNRFNRKGARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKD
WEYVKAAVEGSSFYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLQSLRFRLWDEKSNN
FVSFKDVKNIIKNNVSVRVKSEL
>Mature_342_residues
TLENTKNLKKQVAPFEKSTIKKSVWQLINTIVPFIILWYLAYKSLSVSYWLTLVPALLAAGFMTRIFIIFHDCTHYSFFK
SRRANRIVGTCMGVLTLFPFDQWGHEHSIHHATSGNLDKRGTGDIWTLTVDEYVAAPFRLRLAYRLYRNPFVMFGLGPIY
VFLLKNRFNRKGARQKERMNTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKDW
EYVKAAVEGSSFYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTITLATSLQSLRFRLWDEKSNNF
VSFKDVKNIIKNNVSVRVKSEL

Specific function: Catalyzes the introduction of a cis-double bond at the delta(5) position of existing saturated fatty acids attached to membrane phospholipids. It is not strictly specific for palmitic acid (C16) but can also accept C14 as well as C18 species to yield unsa

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: 1.14.99.-

Molecular weight: Translated: 39806; Mature: 39675

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLENTKNLKKQVAPFEKSTIKKSVWQLINTIVPFIILWYLAYKSLSVSYWLTLVPALLA
CCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGFMTRIFIIFHDCTHYSFFKSRRANRIVGTCMGVLTLFPFDQWGHEHSIHHATSGNLDK
HHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCC
RGTGDIWTLTVDEYVAAPFRLRLAYRLYRNPFVMFGLGPIYVFLLKNRFNRKGARQKERM
CCCCCEEEEEHHHHHCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCHHHHHH
NTYLTNIIIVAVVAILCWAIGWQSFLLVHGTIFLIAGSVGIWLFYVQHTFEDSYFEEDKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCC
WEYVKAAVEGSSFYKLPKILQFLTGNIGFHHVHHLSPRVPNYKLEEAHNNTLPLKNVPTI
HHHHHHHHCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCHHHCCCCCCCCCCCCCC
TLATSLQSLRFRLWDEKSNNFVSFKDVKNIIKNNVSVRVKSEL
HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCEEEEECCC
>Mature Secondary Structure 
TLENTKNLKKQVAPFEKSTIKKSVWQLINTIVPFIILWYLAYKSLSVSYWLTLVPALLA
CCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9555904; 9384377 [H]