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The map label for this gene is cysH [H]

Identifier: 218234802

GI number: 218234802

Start: 1414242

End: 1414946

Strand: Direct

Name: cysH [H]

Synonym: BCB4264_A1476

Alternate gene names: 218234802

Gene position: 1414242-1414946 (Clockwise)

Preceding gene: 218233899

Following gene: 218235386

Centisome position: 26.1

GC content: 36.6

Gene sequence:

>705_bases
ATGTTGACGTATGAAACGTGGGAAGAAAATGTTGTTTCGTTTTCGGAAGAAGATGAAACAAAAGGTGCGTTATCAGTATT
AAATTGGGCTTATAAAGAATATAAAGATGAGGTTGTCTACGCATGTAGCTTTGGGGTGGAAGGTATGGTATTGCTGCACA
TTATAAACCAAGTAAATCCATCTGCTAAAGTTGTATTTTTGGATACAAATGTTCATTTTCAAGAAACGTATGAATTAATT
CAAAAAGTGCGGGAACGATTTCCTTCATTGAATATTATAGAAAAACAGCCAGAACTTACACTTGATGAACAGGCGAAGTT
GCATGGTGAAAAACTGTGGGAGAGCAATCCGAATCTTTGTTGTAAGATTAGAAAAATTTTACCTTTAGAAAAATCATTAG
TCGTGGAAAAAGCATGGATATCGGGCTTAAGAAGGGAACAATCAGAAACACGTAAGCATACAAAGTTTATAAATCAAGAT
CATCGTTTTCAATCTATTAAAGTTTGTCCACTCATTCATTGGACGTGGAAAGAAGTTTGGCGATATGTATACAAACATAG
CTTGCCGTATAACCCGTTGCATGATGTTGGCTATCCAAGTATTGGGTGTGAGAAATGTACGTTACCTGTAGGGGATGGTG
GCGATTCAAGAGATGGTAGATGGGCTGGAAAAGTGAAAACTGAATGTGGTCTTCATTACCAATAA

Upstream 100 bases:

>100_bases
ACGTTTAAAGTGAAAAGCGCTGACTAGAAAAACTAGAGGCGGTTTTAACCTATTTTCATTAGGTTAAAACCGTCTTTTTG
CTTTTACAGGGGGAAAAAAC

Downstream 100 bases:

>100_bases
GATGAATCTTGAAATAAAGCGAAGAGAGGATATAGAAAAATGAGCATAGTAAACGGATTAGTAAACCGTATAGATGAGAC
ATATGACGTATCACAAATTG

Product: phosphoadenylyl-sulfate reductase (thioredoxin)

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLCCKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ

Sequences:

>Translated_234_residues
MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLCCKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ
>Mature_234_residues
MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNPSAKVVFLDTNVHFQETYELI
QKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLCCKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQD
HRFQSIKVCPLIHWTWKEVWRYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=209, Percent_Identity=33.4928229665072, Blast_Score=107, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6325425, Length=202, Percent_Identity=31.6831683168317, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 27314; Mature: 27314

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNP
CCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCC
SAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLC
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCE
CKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVW
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHH
RYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ
HHHHHCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCEECCCEECCCCCCCC
>Mature Secondary Structure
MLTYETWEENVVSFSEEDETKGALSVLNWAYKEYKDEVVYACSFGVEGMVLLHIINQVNP
CCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCC
SAKVVFLDTNVHFQETYELIQKVRERFPSLNIIEKQPELTLDEQAKLHGEKLWESNPNLC
CCEEEEEECCCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCCE
CKIRKILPLEKSLVVEKAWISGLRREQSETRKHTKFINQDHRFQSIKVCPLIHWTWKEVW
EHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECEEEEHHHHHHH
RYVYKHSLPYNPLHDVGYPSIGCEKCTLPVGDGGDSRDGRWAGKVKTECGLHYQ
HHHHHCCCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA