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The map label for this gene is hutM [H]

Identifier: 218234571

GI number: 218234571

Start: 481654

End: 483075

Strand: Direct

Name: hutM [H]

Synonym: BCB4264_A0496

Alternate gene names: 218234571

Gene position: 481654-483075 (Clockwise)

Preceding gene: 218233836

Following gene: 218231572

Centisome position: 8.89

GC content: 37.13

Gene sequence:

>1422_bases
ATGATGAATCAAAATCAAGGATTAAAAAGAGAATTGAAAAGCAGGCACATATTTATGATTGCACTTGGAGGCGTTATTGG
TACCGGTCTTTTTTTAGGATCTGGGTATACAATTCATGAAGCTGGGCCTGGAGGAGCTATTGTAGCATATCTTGTTGGAG
GATTTGTTATGTATTTAACGATGCTCTGTCTTGGAGAGTTAGCTGTTGCAATGCCTGACGCAGGATCTTATCAAACGTAT
GCTACGAAGCATATTTCCCCTGCAGCGGGTTATGTAGTTGGATGGATGTCATGGTTAAACTGGTCAGCTACGATAGGGAT
TGAACTAATTGCAGTTAGTATTTTAATGAAGCGATGGTTTCCAGATGTACCTTCATGGATTTGGTGCGTAGTGTTTGCGT
TACTCCTCTTTGCTATTAATGCGTTATCTTCAAGAAGTTTTGCGGAAGTTGAATTTTGGTTTGCAAGTATTAAAGTAATT
ACGATCATTGCATTTATTATTTTGGGCGGGGCAGCAATGTTTGGTTTTCTAGATATGAAAGGAAATGAACCAGCACCGAT
GTTCTCTAGTTTTACTGATTATGGTGGATTGTTCCCAAATGGATTATCAGCTATTTTAATTACGATGATTGCAGTTAATT
TTTCTTTCCAAGGAACGGAACTAGTCGGTATTGCAGCAGGTGAGAGTGAAAATCCAGAGAAAACAATCCCGAAGGCAATT
AACAATACAGTTTGGCGTATACTTGTTTTCTTTGTACTATCTATTTTTATTCTTGCTGGACTATTCCCTTGGCAACAAGC
AGGAGTAATAGAAAGTCCATTTGTAGTTGTATTTGATAAAATTGGTATTCCTTATGCAGCAGATATTATAAATTTTGTTA
TCATTACAGCAGTGCTATCCGTTGCGAATTCAGGATTATATGCAACTTCTCGTATGCTATGGTCTATGTCTAATCAAGGA
ATGATTAGTCCGATTTTTGGTAAGTTATCTAAAAACGGTGTTCCTATTTATGCATTGATTGTAAGTACAATTGTAGGTTG
CCTTTCATTACTATCAGGTATTTATGCGGAAGATACAGTTTATTTATGGCTACTTTCTATTGCCGGGTTCGGGGCGATAT
TAGTTTGGGCATCTATTGCTCTATCTAACTTATTAGCTAGGAGGTCATACATAAAGCAGGGCGGGGATGTGAAAGAATTG
AAATTTAAAACACCTCTGTATCCATTCGTACCACTGCTTGCACTAGTATTAAATGTAACAGTAATTATTGGTATGGCCTT
TATTCCAGAACAAAGAATGGCATTGTATTGCGGAATTCCATTTATGATTGTTTGTTTACTGTTTTACCGTGCGACAAGAA
ATAAGGCACGTAAAGTAGAACATATTGAAAAGACAAATACGACGGAAGTAGAGAGCTTCTAA

Upstream 100 bases:

>100_bases
TGACGTGTATTTTTGCTCTTTTAAATCATTATTTTTACGGTGAATAATTTTAAAAACGCTTACATTAAATGGGTTTACAA
AGTGAAAAGGGGGGATTTAT

Downstream 100 bases:

>100_bases
TATGAATTAATTTGGAGACTGTAAGATTTGTAAACAGTCTCTTTTTTTGTGAAAATAAAGTTGGAAACATACTACGTATG
TAAAGGGGAATTAGCGATGA

Product: amino acid permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFALLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKEL
KFKTPLYPFVPLLALVLNVTVIIGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKARKVEHIEKTNTTEVESF

Sequences:

>Translated_473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFALLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKEL
KFKTPLYPFVPLLALVLNVTVIIGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKARKVEHIEKTNTTEVESF
>Mature_473_residues
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLTMLCLGELAVAMPDAGSYQTY
ATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWFPDVPSWIWCVVFALLLFAINALSSRSFAEVEFWFASIKVI
TIIAFIILGGAAMFGFLDMKGNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLSVANSGLYATSRMLWSMSNQG
MISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTVYLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKEL
KFKTPLYPFVPLLALVLNVTVIIGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKARKVEHIEKTNTTEVESF

Specific function: Transporter For The Intake Of S-Methylmethionine. [C]

COG id: COG0833

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081708, Length=464, Percent_Identity=51.7241379310345, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1788480, Length=464, Percent_Identity=41.5948275862069, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=463, Percent_Identity=37.7969762419007, Blast_Score=303, Evalue=1e-83,
Organism=Escherichia coli, GI48994972, Length=471, Percent_Identity=36.3057324840764, Blast_Score=295, Evalue=4e-81,
Organism=Escherichia coli, GI1786789, Length=453, Percent_Identity=37.0860927152318, Blast_Score=292, Evalue=4e-80,
Organism=Escherichia coli, GI1789017, Length=454, Percent_Identity=37.2246696035242, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1786602, Length=458, Percent_Identity=37.117903930131, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI87081915, Length=426, Percent_Identity=37.0892018779343, Blast_Score=273, Evalue=2e-74,
Organism=Escherichia coli, GI1790653, Length=441, Percent_Identity=36.0544217687075, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI87081869, Length=257, Percent_Identity=28.0155642023346, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87082250, Length=471, Percent_Identity=23.3545647558386, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI2367353, Length=350, Percent_Identity=26, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87082023, Length=224, Percent_Identity=27.6785714285714, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=438, Percent_Identity=21.4611872146119, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=375, Percent_Identity=22.4, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17531343, Length=431, Percent_Identity=21.5777262180974, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17533459, Length=434, Percent_Identity=24.4239631336406, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320772, Length=440, Percent_Identity=34.7727272727273, Blast_Score=245, Evalue=9e-66,
Organism=Saccharomyces cerevisiae, GI6324061, Length=501, Percent_Identity=31.3373253493014, Blast_Score=242, Evalue=1e-64,
Organism=Saccharomyces cerevisiae, GI6324553, Length=405, Percent_Identity=34.320987654321, Blast_Score=233, Evalue=4e-62,
Organism=Saccharomyces cerevisiae, GI6320717, Length=502, Percent_Identity=28.6852589641434, Blast_Score=223, Evalue=5e-59,
Organism=Saccharomyces cerevisiae, GI6319824, Length=417, Percent_Identity=30.9352517985612, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6324059, Length=429, Percent_Identity=34.032634032634, Blast_Score=221, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6322892, Length=409, Percent_Identity=33.4963325183374, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324990, Length=482, Percent_Identity=29.6680497925311, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6319543, Length=418, Percent_Identity=30.1435406698565, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6320251, Length=418, Percent_Identity=30.1435406698565, Blast_Score=207, Evalue=4e-54,
Organism=Saccharomyces cerevisiae, GI6321053, Length=423, Percent_Identity=28.8416075650118, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6319542, Length=417, Percent_Identity=29.7362110311751, Blast_Score=199, Evalue=7e-52,
Organism=Saccharomyces cerevisiae, GI6321629, Length=481, Percent_Identity=28.2744282744283, Blast_Score=199, Evalue=8e-52,
Organism=Saccharomyces cerevisiae, GI6324924, Length=506, Percent_Identity=29.4466403162055, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6322967, Length=506, Percent_Identity=26.8774703557312, Blast_Score=188, Evalue=1e-48,
Organism=Saccharomyces cerevisiae, GI6324981, Length=484, Percent_Identity=29.3388429752066, Blast_Score=176, Evalue=9e-45,
Organism=Saccharomyces cerevisiae, GI6319608, Length=433, Percent_Identity=25.8660508083141, Blast_Score=166, Evalue=5e-42,
Organism=Saccharomyces cerevisiae, GI6320364, Length=488, Percent_Identity=23.9754098360656, Blast_Score=104, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24667468, Length=369, Percent_Identity=22.4932249322493, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221512776, Length=410, Percent_Identity=20.2439024390244, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24666159, Length=410, Percent_Identity=20.2439024390244, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 51680; Mature: 51680

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVPSWIWCVVFALLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKELKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
VIIGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKARKVEHIEKTNTTEVESF
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMNQNQGLKRELKSRHIFMIALGGVIGTGLFLGSGYTIHEAGPGGAIVAYLVGGFVMYLT
CCCCCCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
MLCLGELAVAMPDAGSYQTYATKHISPAAGYVVGWMSWLNWSATIGIELIAVSILMKRWF
HHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
PDVPSWIWCVVFALLLFAINALSSRSFAEVEFWFASIKVITIIAFIILGGAAMFGFLDMK
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECC
GNEPAPMFSSFTDYGGLFPNGLSAILITMIAVNFSFQGTELVGIAAGESENPEKTIPKAI
CCCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHHHH
NNTVWRILVFFVLSIFILAGLFPWQQAGVIESPFVVVFDKIGIPYAADIINFVIITAVLS
HHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHH
VANSGLYATSRMLWSMSNQGMISPIFGKLSKNGVPIYALIVSTIVGCLSLLSGIYAEDTV
HHCCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHH
YLWLLSIAGFGAILVWASIALSNLLARRSYIKQGGDVKELKFKTPLYPFVPLLALVLNVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
VIIGMAFIPEQRMALYCGIPFMIVCLLFYRATRNKARKVEHIEKTNTTEVESF
HHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704263; 9384377; 8550462; 8867804 [H]