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The map label for this gene is ntdR [H]

Identifier: 218234544

GI number: 218234544

Start: 1095901

End: 1096914

Strand: Direct

Name: ntdR [H]

Synonym: BCB4264_A1118

Alternate gene names: 218234544

Gene position: 1095901-1096914 (Clockwise)

Preceding gene: 218234381

Following gene: 218233583

Centisome position: 20.22

GC content: 38.36

Gene sequence:

>1014_bases
GTGTCGACTATAGAGGACGTGGCGAAATTAGCAGGGTTATCAAGGACAACGGTTTCTAGGGTGATTAATAATCATCCATA
TGTTTCAGATGAGAAGAAAAAAAGGGTTCAATTAGCAATGAAGCATTTAGGCTTCGTTCCTAATTCTGCGGCGAGAAGGC
TTCGTAAACAAAAAACGGAAACAATTGCGGTGCTAGTTCCAAGGATTACAAATCCTTTCTTCAGTAGATTTATTGAAGCA
ATCGAGATTGCTGCTTCTGAACATAAATATAAACTGATTATTTGTCAAACAAGGTATTTACCGGAAAAAGAGATGGAGTA
TTTACAATTATTATCTACGAAACAAGTAGATGGGATTATTCTATGTTCACTAGAAAATCCGTGGGAAGATGTAGAGCCAT
ACTTACAGCACGGTCCAATCGTGTTGTGTAATGAATATATTGAGGAAGCAAATATTCCAACAGTGAAATTTGATCATGCG
CAAGGAGCATACATAGCTGCGAAGCATGTGTTAGATCAAGGATATCGTAATCTTATTTTTTGCCGTGGTAACGAAACCAA
AGTCGTTAGCCAGCAGCGAAAAATGGGCTTTTTACGTGCAATAACTGAGAAGAGCCGCCAAGTAGAAGCGATTGACTTTA
TTGAAAACGCTTTCTATTGGGAAGATGGAAAACGAATATTCCATGAAGTATTAAAGGACAAAAAAAATCCTACCGCGATT
TTGGCAGGAGGCGATGAGGTAGCAGCTGGAATTATCTCAGAGGCGAAACGCCATAACTGGAGCATTCCAGATGATCTCGC
TGTTATCGGTTTTGATAATCAAATATTATCGCAGATTACAGAACCAGGTATTACGACAATTGAACAGCCAATTGATGAAA
TGGCCCGAAAAGTTGTCGACCTAATGATGGATAAAATTCATACGAAAAATTATCGAAAAAAAGAATTGTATGAGTTTGAA
CTGGAGCTCTTGGTGAAAGGTTCAACGATGAAGGATAAGATGTTATTAGCCTAG

Upstream 100 bases:

>100_bases
TATTAATATAGTAAAATCATAACAACCGATATTGCAGTTTCCAATAATATACTATATAATCAATTTAAGAAAACGTTTTC
ATGCAAAGGGGGAGAATTTC

Downstream 100 bases:

>100_bases
TAGACTATGTCTGCTAGGTTTTTTTCTGTTCACAAACTACTATTCTTCGTGAACGCAATCATCACATTTGTTATGGTATG
CTTCGTGCTGCTCATCAATT

Product: sugar-binding transcriptional regulator, LacI family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFIENAFYWEDGKRIFHEVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFE
LELLVKGSTMKDKMLLA

Sequences:

>Translated_337_residues
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEA
IEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHA
QGAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFIENAFYWEDGKRIFHEVLKDKKNPTAI
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFE
LELLVKGSTMKDKMLLA
>Mature_336_residues
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTETIAVLVPRITNPFFSRFIEAI
EIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGIILCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQ
GAYIAAKHVLDQGYRNLIFCRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFIENAFYWEDGKRIFHEVLKDKKNPTAIL
AGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVDLMMDKIHTKNYRKKELYEFEL
ELLVKGSTMKDKMLLA

Specific function: Positively regulates the ntdABC operon and negatively regulates its own transcription. Binds to NTD to induce ntdABC transcription [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=329, Percent_Identity=31.6109422492401, Blast_Score=197, Evalue=6e-52,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=31.0126582278481, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1790194, Length=318, Percent_Identity=27.6729559748428, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1789202, Length=301, Percent_Identity=29.9003322259136, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1788474, Length=311, Percent_Identity=27.9742765273312, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI48994940, Length=329, Percent_Identity=24.0121580547112, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1789068, Length=327, Percent_Identity=23.5474006116208, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=26.4984227129338, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790715, Length=319, Percent_Identity=22.884012539185, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1786268, Length=333, Percent_Identity=24.3243243243243, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1790689, Length=312, Percent_Identity=23.7179487179487, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786540, Length=325, Percent_Identity=23.6923076923077, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787906, Length=324, Percent_Identity=20.0617283950617, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789456, Length=317, Percent_Identity=21.7665615141956, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 38606; Mature: 38475

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLDQGYRNLIF
EEECCCCHHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEE
CRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFIENAFYWEDGKRIFHEVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVD
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LMMDKIHTKNYRKKELYEFELELLVKGSTMKDKMLLA
HHHHHHHCCCCHHHHHHHHEEEHEEECCCCCCCCCCC
>Mature Secondary Structure 
STIEDVAKLAGLSRTTVSRVINNHPYVSDEKKKRVQLAMKHLGFVPNSAARRLRKQKTE
CCHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
TIAVLVPRITNPFFSRFIEAIEIAASEHKYKLIICQTRYLPEKEMEYLQLLSTKQVDGII
EEEEEECHHCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCCEEE
LCSLENPWEDVEPYLQHGPIVLCNEYIEEANIPTVKFDHAQGAYIAAKHVLDQGYRNLIF
EEECCCCHHHHHHHHHCCCEEEEHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCEEEE
CRGNETKVVSQQRKMGFLRAITEKSRQVEAIDFIENAFYWEDGKRIFHEVLKDKKNPTAI
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
LAGGDEVAAGIISEAKRHNWSIPDDLAVIGFDNQILSQITEPGITTIEQPIDEMARKVVD
EECCHHHHHHHHHHHHHCCCCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LMMDKIHTKNYRKKELYEFELELLVKGSTMKDKMLLA
HHHHHHHCCCCHHHHHHHHEEEHEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]