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The map label for this gene is glnA [H]

Identifier: 218234274

GI number: 218234274

Start: 3711892

End: 3713226

Strand: Reverse

Name: glnA [H]

Synonym: BCB4264_A3803

Alternate gene names: 218234274

Gene position: 3713226-3711892 (Counterclockwise)

Preceding gene: 218234632

Following gene: 218233539

Centisome position: 68.52

GC content: 38.73

Gene sequence:

>1335_bases
ATGTCTAGATACACAAAAGAAGATATTTTCCGTTTGGCGAAAGAAGAGAATGTAAAGTATATCCGTTTACAATTTACGGA
CCTTTTAGGGGTAATTAAAAACGTAGAGATTCCAGTGAGACAATTAACGAAAGCTCTTGATAACAAAATGATGTTTGATG
GATCTTCGATTGAAGGTTTCGTACGTATTGAAGAGTCTGATATGTATTTATATCCTGATTTAGACACTTGGGTAATTTTC
CCTTGGACAGCTGAAAAAGGTAAAGTAGCTCGACTAATCTGTGATATTTACAATGCAGATGGCACTCCATTTGATGGAGA
CCCACGTAACAACTTAAAACGTGTGTTAAAAGAAATGGAAGCTTTAGGATTTTCAGACTTCAATCTTGGACCAGAGCCAG
AATTCTTCCTATTTAAGGTTGATGAAAAAGGAAATCCAACATTAGAACTAAACGATAACGGTGGATACTTCGACCTTGCG
CCGATGGATCTAGGGGAAAACTGTCGTCGTGATATCGTTCTTGAACTTGAAGAAATGGGATTTGAAATTGAAGCATCTCA
CCATGAGGTTGCTCCAGGACAGCACGAAATTGACTTTAAATATGCAAATGCAATTCGCTCATGTGATGACATTCAAACAT
TCAAACTTGTTGTAAAAACAATTGCTCGTAAACATGGTTTACACGCAACGTTTATGCCAAAACCACTATACGGTGTGAAC
GGTTCAGGTATGCACTGTAACTTATCATTATTTAAAAATGGTGAGAACGTATTCTTTGATGCAAACGGTGACTTACAATT
AAGTGATGATGCTCGTCACTTCATCGCAGGTATTTTAAAACATGCACCAGCATTTACAGCGATAGCAAACCCAACTGTAA
ACTCATATAAACGTCTAGTACCTGGATATGAAGCGCCTTGTTACGTAGCATGGTCTGCACAAAACCGTAGTCCGTTAGTA
CGTATCCCTGCATCTCGTGGTATTAGTACACGCGTAGAAGTACGTAGTGTTGACCCAGCTGCAAACCCATATTTAGTAAT
GGCTACATTATTAGCTGCAGGTCTTGATGGAATTAAAAACAAATTAACTCCACCAGCAGCAGTAGATCGTAACATCTATG
TAATGACAAAAGAAGAGCGCGAAGAAGCAGGTATCGTTGACTTACCAGCAACATTAGCGCAAGCATTAGTTACATTACAA
TCTAATGAAGTAGTATGCGGTGCACTAGGAGAACACTTACTTGAGCACTTCATCGAAGCGAAAGAGATTGAGTGGGATAT
CTTTAGAACACAAGTTCACCAATGGGAACGCGATCAATATATGTCTCTATACTAA

Upstream 100 bases:

>100_bases
ATTCAATCGAACTTCATTGCGACAAGGTGACATTTCAAGATTTTTTCACTAAAGATAACTGATTCTGAAGGCGATTAGAG
GGACTAAGGAGGAATTTATA

Downstream 100 bases:

>100_bases
GAGGCTTGAACCCTTGATACAACTCGTATCAAGGGTTTTTTAATTCCCTATTATTACAATTTTATGTGGTTGCAAAATGA
AAAATAGCCACATAAAAGCC

Product: glutamine synthetase, type I

Products: NA

Alternate protein names: Glutamate--ammonia ligase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIF
PWTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLA
PMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVN
GSGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLV
RIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQ
SNEVVCGALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY

Sequences:

>Translated_444_residues
MSRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIF
PWTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLA
PMDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVN
GSGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLV
RIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQ
SNEVVCGALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY
>Mature_443_residues
SRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGFVRIEESDMYLYPDLDTWVIFP
WTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEMEALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAP
MDLGENCRRDIVLELEEMGFEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVNG
SGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLVPGYEAPCYVAWSAQNRSPLVR
IPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKNKLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQS
NEVVCGALGEHLLEHFIEAKEIEWDIFRTQVHQWERDQYMSLY

Specific function: Unknown

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=432, Percent_Identity=27.3148148148148, Blast_Score=142, Evalue=7e-34,
Organism=Escherichia coli, GI1790301, Length=476, Percent_Identity=41.8067226890756, Blast_Score=318, Evalue=4e-88,
Organism=Escherichia coli, GI87081870, Length=462, Percent_Identity=29.8701298701299, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI281360453, Length=360, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI17136208, Length=360, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24580558, Length=360, Percent_Identity=26.6666666666667, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 15324 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal medi

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146
- InterPro:   IPR004809
- InterPro:   IPR001637 [H]

Pfam domain/function: PF00120 Gln-synt_C; PF03951 Gln-synt_N [H]

EC number: =6.3.1.2 [H]

Molecular weight: Translated: 50133; Mature: 50001

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00180 GLNA_1 ; PS00181 GLNA_ATP ; PS00182 GLNA_ADENYLATION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGF
CCCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEME
EEEECCCEEEECCCCCEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHH
ALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMG
HCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCCCCCCCHHHEEEHHHCC
FEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVN
EEEECCCCCCCCCCCEECCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GSGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLV
CCCCEEEEEEEECCCEEEEECCCCEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHC
PGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKN
CCCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVVCGALGEHLLEHFIEA
CCCCCCCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
KEIEWDIFRTQVHQWERDQYMSLY
HHCHHHHHHHHHHHCCCCHHEECC
>Mature Secondary Structure 
SRYTKEDIFRLAKEENVKYIRLQFTDLLGVIKNVEIPVRQLTKALDNKMMFDGSSIEGF
CCCCHHHHHHHHHHCCCEEEEEEHHHHHHHHHCCCCCHHHHHHHHCCCEEECCCCCCEE
VRIEESDMYLYPDLDTWVIFPWTAEKGKVARLICDIYNADGTPFDGDPRNNLKRVLKEME
EEEECCCEEEECCCCCEEEEEEECCCCCCEEEEHHHCCCCCCCCCCCCHHHHHHHHHHHH
ALGFSDFNLGPEPEFFLFKVDEKGNPTLELNDNGGYFDLAPMDLGENCRRDIVLELEEMG
HCCCCCCCCCCCCCEEEEEECCCCCCEEEECCCCCEEEECCCCCCCCCCHHHEEEHHHCC
FEIEASHHEVAPGQHEIDFKYANAIRSCDDIQTFKLVVKTIARKHGLHATFMPKPLYGVN
EEEECCCCCCCCCCCEECCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCC
GSGMHCNLSLFKNGENVFFDANGDLQLSDDARHFIAGILKHAPAFTAIANPTVNSYKRLV
CCCCEEEEEEEECCCEEEEECCCCEEECCHHHHHHHHHHHHCCCEEEECCCCHHHHHHHC
PGYEAPCYVAWSAQNRSPLVRIPASRGISTRVEVRSVDPAANPYLVMATLLAAGLDGIKN
CCCCCCEEEEECCCCCCCEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHH
KLTPPAAVDRNIYVMTKEEREEAGIVDLPATLAQALVTLQSNEVVCGALGEHLLEHFIEA
CCCCCCCCCCCEEEEECCCCCCCCEEECHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHH
KEIEWDIFRTQVHQWERDQYMSLY
HHCHHHHHHHHHHHCCCCHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2572584 [H]