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The map label for this gene is dsdA

Identifier: 218234235

GI number: 218234235

Start: 1700297

End: 1701628

Strand: Direct

Name: dsdA

Synonym: BCB4264_A1796

Alternate gene names: 218234235

Gene position: 1700297-1701628 (Clockwise)

Preceding gene: 218235757

Following gene: 218232667

Centisome position: 31.38

GC content: 36.64

Gene sequence:

>1332_bases
ATGAAAGAAATAGGGGCATTACAAGCAGAATACCCATTAGTGAATAAACTTATTGCAACAGAAGAAGTATTTTGGATAAA
CCCACACATAGAAAAGTATGAAAGGGCAATAAAAGATTCACCACTTAATGAAGAGAATGTAAAAGATGCGGAAGAGAGAT
TAAAGCGTTTTGCACCATATATTGCGAAAGTTTTTCCTGAAACGAAAGGGACGAACGGCATAATCGAATCACCTTTAGTG
AAAATATCTTCTATGAAAGAAGCTTTAGAGACAACTTACAAGCAACCTATTTCAGGAGAATTATTATTAAAATGTGATAG
TCATCTTCCAATATCAGGATCAATTAAAGCTAGGGGTGGCATTTATGAAGTGCTAAAATATGCTGAACAATTAGCTTTGC
AGCACGGTATGTTAACAGAAGAAGATGATTATTCCATTTTAGATAGTGATACATGTAGAGAGTTTTTTGCCAAACATTCA
ATTGCAGTAGGTTCTACAGGGAATTTAGGACTTAGCATAGGGATTATGAGTGCGAATCTAGGTTTTAATGTAACTGTTCA
TATGTCAGCAGACGCAAAAGAATGGAAGAAAGATTTATTAAGAAGTAAAGGTGTAAACGTTATTGAATATGAAGATGATT
ATAGTAAAGCAGTAGAAGAAGGAAGAAGACAAGCGGATGCGGATCCTAGCTGTTATTTTGTAGACGATGAAAACTCACAT
GATTTATTTTTAGGATACGCAGTAGCAGCATCACGATTACAAAAGCAATTAGAAGAGTTAGAGGTTGTAGTAGATAAAGA
CCATCCTTTATTTGTTTACCTTCCGTGCGGAGTAGGAGGAGGACCGGGTGGAGTAGCATTCGGTTTAAAGTTATTGTATA
AAGACAATGTTCATTGTTTCTTTGCAGAGCCTACGCACTCTCCATGTATGTTACTCGGCTTAATGACAGGCCTTCATGAC
AAAATTGCCGTTCAAGATATCGGAATTGATAATGTAACGGATGCGGATGGACTTGCGGTAGGAAGGCCATCTGGATTTGT
CGGGAAAACGATGGAACCATTTTTGAGTGGGAATTACACAGTAAGCGATGAAGAGTTATATAGATTGTTAAAAGAACTAG
CTGATACGGAGAATATTTATTTAGAGCCTTCTGCACTAGCAGGTATGATAGGGCCAGTGAAAGTATGTAAAGAAGATGAG
TATTTACAAAAGCAACAGTTAACAGAGAAGGTGAAAAAAGGTACTCATATTGTGTGGGGAACGGGTGGAAGTATGGTTCC
AAAAGATGTAATGAATGAATATTATAGGAAAGGTTTGGAATTAACGGTATAA

Upstream 100 bases:

>100_bases
AAAATTAACTAAAGTGAACGATTTGTGTTAAACTATATTAAAATTAATTTAATTATAATTTATTATATGGTGAGCTACAA
GGATATAAGGAGGAAACAAA

Downstream 100 bases:

>100_bases
GAAAAATGAGGCTAGTTGTAGCCTCATTTTTTCATGTACATAAAAATCTTTGTTATTTTCACAATAGTTCTTTATAGTAT
ATATAAAGGATAGCTAATAT

Product: D-serine dehydratase

Products: NA

Alternate protein names: D-serine deaminase; DSD

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MKEIGALQAEYPLVNKLIATEEVFWINPHIEKYERAIKDSPLNEENVKDAEERLKRFAPYIAKVFPETKGTNGIIESPLV
KISSMKEALETTYKQPISGELLLKCDSHLPISGSIKARGGIYEVLKYAEQLALQHGMLTEEDDYSILDSDTCREFFAKHS
IAVGSTGNLGLSIGIMSANLGFNVTVHMSADAKEWKKDLLRSKGVNVIEYEDDYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEVVVDKDHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLLGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDE
YLQKQQLTEKVKKGTHIVWGTGGSMVPKDVMNEYYRKGLELTV

Sequences:

>Translated_443_residues
MKEIGALQAEYPLVNKLIATEEVFWINPHIEKYERAIKDSPLNEENVKDAEERLKRFAPYIAKVFPETKGTNGIIESPLV
KISSMKEALETTYKQPISGELLLKCDSHLPISGSIKARGGIYEVLKYAEQLALQHGMLTEEDDYSILDSDTCREFFAKHS
IAVGSTGNLGLSIGIMSANLGFNVTVHMSADAKEWKKDLLRSKGVNVIEYEDDYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEVVVDKDHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLLGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDE
YLQKQQLTEKVKKGTHIVWGTGGSMVPKDVMNEYYRKGLELTV
>Mature_443_residues
MKEIGALQAEYPLVNKLIATEEVFWINPHIEKYERAIKDSPLNEENVKDAEERLKRFAPYIAKVFPETKGTNGIIESPLV
KISSMKEALETTYKQPISGELLLKCDSHLPISGSIKARGGIYEVLKYAEQLALQHGMLTEEDDYSILDSDTCREFFAKHS
IAVGSTGNLGLSIGIMSANLGFNVTVHMSADAKEWKKDLLRSKGVNVIEYEDDYSKAVEEGRRQADADPSCYFVDDENSH
DLFLGYAVAASRLQKQLEELEVVVDKDHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCFFAEPTHSPCMLLGLMTGLHD
KIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYTVSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDE
YLQKQQLTEKVKKGTHIVWGTGGSMVPKDVMNEYYRKGLELTV

Specific function: Unknown

COG id: COG3048

COG function: function code E; D-serine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family. DsdA subfamily

Homologues:

Organism=Escherichia coli, GI1788708, Length=437, Percent_Identity=62.929061784897, Blast_Score=548, Evalue=1e-157,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SDHD_BACC4 (B7HID8)

Other databases:

- EMBL:   CP001176
- RefSeq:   YP_002366515.1
- EnsemblBacteria:   EBBACT00000111297
- GeneID:   7097589
- GenomeReviews:   CP001176_GR
- KEGG:   bcb:BCB4264_A1796
- GeneTree:   EBGT00050000001628
- HOGENOM:   HBG288722
- OMA:   WKKDLLR
- ProtClustDB:   PRK02991
- HAMAP:   MF_01030
- InterPro:   IPR011780
- InterPro:   IPR001926
- InterPro:   IPR000634
- PANTHER:   PTHR10314:SF9
- TIGRFAMs:   TIGR02035

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.3.1.18

Molecular weight: Translated: 49045; Mature: 49045

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIGALQAEYPLVNKLIATEEVFWINPHIEKYERAIKDSPLNEENVKDAEERLKRFAPY
CCCCCCCCCCCHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAKVFPETKGTNGIIESPLVKISSMKEALETTYKQPISGELLLKCDSHLPISGSIKARGG
HHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCC
IYEVLKYAEQLALQHGMLTEEDDYSILDSDTCREFFAKHSIAVGSTGNLGLSIGIMSANL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEEECC
GFNVTVHMSADAKEWKKDLLRSKGVNVIEYEDDYSKAVEEGRRQADADPSCYFVDDENSH
CEEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCC
DLFLGYAVAASRLQKQLEELEVVVDKDHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCF
EEEHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCHHHHHHEEEEECCEEEE
FAEPTHSPCMLLGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYT
EECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHCCCCE
VSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDEYLQKQQLTEKVKKGTHIVWG
ECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEE
TGGSMVPKDVMNEYYRKGLELTV
CCCCCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKEIGALQAEYPLVNKLIATEEVFWINPHIEKYERAIKDSPLNEENVKDAEERLKRFAPY
CCCCCCCCCCCHHHHHHHHHCEEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
IAKVFPETKGTNGIIESPLVKISSMKEALETTYKQPISGELLLKCDSHLPISGSIKARGG
HHHHCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCC
IYEVLKYAEQLALQHGMLTEEDDYSILDSDTCREFFAKHSIAVGSTGNLGLSIGIMSANL
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEEEEEEEECC
GFNVTVHMSADAKEWKKDLLRSKGVNVIEYEDDYSKAVEEGRRQADADPSCYFVDDENSH
CEEEEEEECCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCC
DLFLGYAVAASRLQKQLEELEVVVDKDHPLFVYLPCGVGGGPGGVAFGLKLLYKDNVHCF
EEEHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCCCCCHHHHHHEEEEECCEEEE
FAEPTHSPCMLLGLMTGLHDKIAVQDIGIDNVTDADGLAVGRPSGFVGKTMEPFLSGNYT
EECCCCCHHHHHHHHHCCCCHHEEEECCCCCCCCCCCCEECCCCCCCCCCHHHHHCCCCE
VSDEELYRLLKELADTENIYLEPSALAGMIGPVKVCKEDEYLQKQQLTEKVKKGTHIVWG
ECHHHHHHHHHHHCCCCCEEECHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEE
TGGSMVPKDVMNEYYRKGLELTV
CCCCCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA