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The map label for this gene is mhpC [C]

Identifier: 218234228

GI number: 218234228

Start: 3766266

End: 3767039

Strand: Reverse

Name: mhpC [C]

Synonym: BCB4264_A3857

Alternate gene names: 218234228

Gene position: 3767039-3766266 (Counterclockwise)

Preceding gene: 218235370

Following gene: 218233761

Centisome position: 69.51

GC content: 31.78

Gene sequence:

>774_bases
ATGTATTTTGTATATAAGAATCGAAAGTTTTTTTATAATATAGAAGGATCAGGTCCAGTCATATTGTTTTTACATGGGCT
TGGAGGAAACGCAAATAATTGGTTATATCAAAGGCAATATTTCAAGAAAAAATGGACAGTGATCTCACTTGATTTACCAG
GGAATGGAAAATCTGAAGGGCTAGAAATTAACTTTAAAGAATATGTAAATGTTTTGTATGAGTTATGCAATTATTTAAAG
TTACAAAAAGTAGTCATTTGTGGACTTTCAAAAGGGGCTAGAGTAGGGGTTGATTTTGCTATCCAATATCCAGAATGTGT
TTCTAGCTTAATTATTGTAAATGCATTTCCCTATTTGGAGCCTGAGGATCGAAAGAAGCGGCTTGAAGTATATGATTTGC
TTAGCTTACATGATAACGGGAAAAAATGGGCGGATACATTGTTGAAGGCGATGGGAGTAGCGAATAATGAAGTAATTGTC
AGGGGATTTTATCAATCTTTACAGTTTATTAATCCGGTGCATATTCAAAGATTATTTGCTGAATTAGTAGATTATGATCA
AAGACCATTTCTTTCGAATATTACATGTTCCGCTTTAATTATAAGAGGGGAAAATGATGATTTTGTCCCCGAGAAATATG
TAAGAGAGTTTGAAAGCCGTTTGAAAAATACAACTTTTATTGAGTTTAAAAATAGTGGACACTTACCTTATTTAGAAAAG
CCAAGTAGCTTTAATATGACAGTAGAAAGATTTTTAAATCATGTAATTAATTAA

Upstream 100 bases:

>100_bases
ATGGTGTACCGGAAACAGTCGAGTGGTTAGAAAGAGAACCGTTTTGGATATATTCATTCAAAGATAAAAATAAGTGATGC
TACAGCTGAAGGTGATGAAT

Downstream 100 bases:

>100_bases
TACTATTATTACAGTCAATACTGTTATTAGTGAGTAAAATATAGTTAGTTTTGAGAGGGGGCAACTATATGGAATGGAAA
CCAAATCGTGTAGATAAGAC

Product: hydrolase, alpha/beta fold family

Products: 2-oxopent-4-enoate; succinate [C]

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MYFVYKNRKFFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGNGKSEGLEINFKEYVNVLYELCNYLK
LQKVVICGLSKGARVGVDFAIQYPECVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLKAMGVANNEVIV
RGFYQSLQFINPVHIQRLFAELVDYDQRPFLSNITCSALIIRGENDDFVPEKYVREFESRLKNTTFIEFKNSGHLPYLEK
PSSFNMTVERFLNHVIN

Sequences:

>Translated_257_residues
MYFVYKNRKFFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGNGKSEGLEINFKEYVNVLYELCNYLK
LQKVVICGLSKGARVGVDFAIQYPECVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLKAMGVANNEVIV
RGFYQSLQFINPVHIQRLFAELVDYDQRPFLSNITCSALIIRGENDDFVPEKYVREFESRLKNTTFIEFKNSGHLPYLEK
PSSFNMTVERFLNHVIN
>Mature_257_residues
MYFVYKNRKFFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGNGKSEGLEINFKEYVNVLYELCNYLK
LQKVVICGLSKGARVGVDFAIQYPECVSSLIIVNAFPYLEPEDRKKRLEVYDLLSLHDNGKKWADTLLKAMGVANNEVIV
RGFYQSLQFINPVHIQRLFAELVDYDQRPFLSNITCSALIIRGENDDFVPEKYVREFESRLKNTTFIEFKNSGHLPYLEK
PSSFNMTVERFLNHVIN

Specific function: 3-hydroxyphenylpropionate degradation. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: 3.7.1.- [C]

Molecular weight: Translated: 29895; Mature: 29895

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFVYKNRKFFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGNGKSEG
CEEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
LEINFKEYVNVLYELCNYLKLQKVVICGLSKGARVGVDFAIQYPECVSSLIIVNAFPYLE
EEEEHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECEEEEEECHHHHHHHHHHHCCCCCC
PEDRKKRLEVYDLLSLHDNGKKWADTLLKAMGVANNEVIVRGFYQSLQFINPVHIQRLFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHH
ELVDYDQRPFLSNITCSALIIRGENDDFVPEKYVREFESRLKNTTFIEFKNSGHLPYLEK
HHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PSSFNMTVERFLNHVIN
CCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MYFVYKNRKFFYNIEGSGPVILFLHGLGGNANNWLYQRQYFKKKWTVISLDLPGNGKSEG
CEEEEECCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCC
LEINFKEYVNVLYELCNYLKLQKVVICGLSKGARVGVDFAIQYPECVSSLIIVNAFPYLE
EEEEHHHHHHHHHHHHHHHHHHHHHEECCCCCCEECEEEEEECHHHHHHHHHHHCCCCCC
PEDRKKRLEVYDLLSLHDNGKKWADTLLKAMGVANNEVIVRGFYQSLQFINPVHIQRLFA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEHHHHHHHHHCCHHHHHHHHH
ELVDYDQRPFLSNITCSALIIRGENDDFVPEKYVREFESRLKNTTFIEFKNSGHLPYLEK
HHHCCCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCC
PSSFNMTVERFLNHVIN
CCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-hydroxy-6-ketononadienedicarboxylate; H2O [C]

Specific reaction: 2-hydroxy-6-ketononadienedicarboxylate + H2O = 2-oxopent-4-enoate + succinate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]