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The map label for this gene is aceB [H]

Identifier: 218233990

GI number: 218233990

Start: 1150779

End: 1152368

Strand: Direct

Name: aceB [H]

Synonym: BCB4264_A1181

Alternate gene names: 218233990

Gene position: 1150779-1152368 (Clockwise)

Preceding gene: 218232871

Following gene: 218234752

Centisome position: 21.24

GC content: 38.55

Gene sequence:

>1590_bases
ATGTCGACGCAAACTTCACGGGTTACACTCGTTGGAGAAATGTTACCAGCGTACAGCGAAATATTGACACCTGAGGTGCT
TAGTTTTTTGAAGGAACTACATGAGAATTTTAATGAGCGCCGCATAGAACTTTTACAAAAACGTGTAGAAAAACAAAAGA
GAATTGATGCAGGGGAGTTTCCGAAGTTTCTAGAAGAAACAAAACACATACGTGAAGCGGATTGGACAATTGCCAAGCTG
CCAAAAGACTTAGAGGATCGCCGTGTAGAGATTACTGGACCGGTAGATAGAAAGATGGTCATTAACGCTTTAAATTCAGG
AGCGCATCTTTTTATGGCGGATTTTGAAGATTCGAATTCACCAACTTGGGAAAATGCAGTGGAAGGCCAAATCAATTTAC
GAGATGCAGTAAAGGGAACGATTTCACATGAAAATGATAAAGGGAAAGAATATAGATTAAATGAGAAAACAGCTGTACTC
ATTGTACGTCCAAGAGGATGGCATTTAGAGGAAAAGCATATGCAAGTTGATGGGAAAAATATGTCGGGTAGTTTAGTAGA
TTTCGGTTTGTATTTTTTCCATAATGCGAAAGCTCTTTTAGCAAAAGGGAGCGGCCCATACTTTTACTTACCGAAAATGG
AAAGTTATTTAGAAGCGAGATTATGGAATGATGTATTCGTATTTGCTCAAAAATATATCGGCATTCCAAATGGAACGATT
AAAGCAACTGTGTTACTAGAAACGATTCACGCTTCGTTTGAAATGGATGAAATTTTATATGAGCTAAAAGATCATTCTGC
TGGCTTAAATTGCGGAAGATGGGATTATATTTTTAGCTTTTTAAAGAGTTTCCGTAATCATAATAAATTCTTACTACCAG
ATAGAGCACAAGTCACGATGACGGCGCCATTTATGCGTTCGTATTCTTTGAAAGTAATTCAAACATGTCACCGCCGTAAT
GCACCAGCAATTGGAGGAATGGCGGCACAAATTCCGATTAAAAATAATCCAGAAGCAAATGAAGCAGCTTTTGAAAAAGT
GCGTGCTGATAAGGAACGCGAAGCTTTAGACGGTCATGACGGGACTTGGGTCGCCCACCCTGGACTTGTACCGGTTGCAA
TGGAAGTGTTTAATCACATTATGAAAACACCAAATCAAATTTTTAGAAAACGTGAAGAAATATGTGTAACAGAAAACGAT
TTACTAGAGGTACCGGTGGGAACGATTACAGAAGAGGGCCTTCGCATGAATATTAGCGTAGGTATTCAATATATTGCATC
TTGGTTAAGCGGACGGGGAGCAGCACCCATTTATAACTTAATGGAAGATGCGGCAACAGCTGAAATTTCAAGAGCACAAG
TATGGCAATGGATTCGTCATGAAGGTGGAAAACTAAATGATGGTCGTAATATTACGCTTGAATTAATGGAAGAGCTAAAA
GAAGAAGAATTAGCAAAAATAGAAAGAGAGATTGGTAAGGAAGCCTTTAAGAAAGGGAGATTCCAAGAGGCGACAACGTT
GTTTACAAATCTCGTTCGAAATGATGAATTCGTACCATTTTTAACATTACCGGGTTATGAAATTTTATAA

Upstream 100 bases:

>100_bases
ATGAATTTTCAAAAAAAACTTCCTTTTCTGAAGATTTGTTATATAATATAAAACATGAAATCAAATCTGTTATAAAACAG
TTTAAGAAGGGGATGCTAAT

Downstream 100 bases:

>100_bases
AAAACGAAAAGGGGATGGAACAAATGAAAAACGAAAGAATCGAGAAGTTGCAAGAAAGCTGGGAATTAGATGAGCGTTGG
AAAGGGATCACACGTCCATA

Product: malate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MSTQTSRVTLVGEMLPAYSEILTPEVLSFLKELHENFNERRIELLQKRVEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAVEGQINLRDAVKGTISHENDKGKEYRLNEKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKSFRNHNKFLLPDRAQVTMTAPFMRSYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEICVTEND
LLEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELAKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Sequences:

>Translated_529_residues
MSTQTSRVTLVGEMLPAYSEILTPEVLSFLKELHENFNERRIELLQKRVEKQKRIDAGEFPKFLEETKHIREADWTIAKL
PKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAVEGQINLRDAVKGTISHENDKGKEYRLNEKTAVL
IVRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKSFRNHNKFLLPDRAQVTMTAPFMRSYSLKVIQTCHRRN
APAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEICVTEND
LLEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
EEELAKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
>Mature_528_residues
STQTSRVTLVGEMLPAYSEILTPEVLSFLKELHENFNERRIELLQKRVEKQKRIDAGEFPKFLEETKHIREADWTIAKLP
KDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNSPTWENAVEGQINLRDAVKGTISHENDKGKEYRLNEKTAVLI
VRPRGWHLEEKHMQVDGKNMSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTIK
ATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKSFRNHNKFLLPDRAQVTMTAPFMRSYSLKVIQTCHRRNA
PAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHDGTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEICVTENDL
LEVPVGTITEEGLRMNISVGIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELKE
EELAKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL

Specific function: Glyoxylate bypass; second step. [C]

COG id: COG2225

COG function: function code C; Malate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the malate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1790444, Length=512, Percent_Identity=54.4921875, Blast_Score=570, Evalue=1e-164,
Organism=Caenorhabditis elegans, GI17561814, Length=525, Percent_Identity=56.3809523809524, Blast_Score=593, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI71982926, Length=418, Percent_Identity=59.3301435406699, Blast_Score=509, Evalue=1e-145,
Organism=Saccharomyces cerevisiae, GI6324212, Length=515, Percent_Identity=51.2621359223301, Blast_Score=526, Evalue=1e-150,
Organism=Saccharomyces cerevisiae, GI6322222, Length=517, Percent_Identity=49.7098646034816, Blast_Score=509, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011076
- InterPro:   IPR006252
- InterPro:   IPR001465
- InterPro:   IPR019830 [H]

Pfam domain/function: PF01274 Malate_synthase [H]

EC number: =2.3.3.9 [H]

Molecular weight: Translated: 60502; Mature: 60371

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00510 MALATE_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQTSRVTLVGEMLPAYSEILTPEVLSFLKELHENFNERRIELLQKRVEKQKRIDAGEF
CCCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAVEGQINLRDAVKGTISHENDKGKEYRLNEKTAVLIVRPRGWHLEEKHMQVDGKN
CCCCCCCCCCEEHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
CCCHHHHHHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKSFRNHNKFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEE
TAPFMRSYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEICVTENDLLEVPVGTITEEGLRMNISV
CCEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEHHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELAKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
STQTSRVTLVGEMLPAYSEILTPEVLSFLKELHENFNERRIELLQKRVEKQKRIDAGEF
CCCCCCEEHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
PKFLEETKHIREADWTIAKLPKDLEDRRVEITGPVDRKMVINALNSGAHLFMADFEDSNS
HHHHHHHHHHHHCCCHHHHCCCCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCC
PTWENAVEGQINLRDAVKGTISHENDKGKEYRLNEKTAVLIVRPRGWHLEEKHMQVDGKN
CCCCCCCCCCEEHHHHHHHCCCCCCCCCCCEEECCCEEEEEECCCCCCCCHHHHEECCCC
MSGSLVDFGLYFFHNAKALLAKGSGPYFYLPKMESYLEARLWNDVFVFAQKYIGIPNGTI
CCCHHHHHHHHHHHCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCE
KATVLLETIHASFEMDEILYELKDHSAGLNCGRWDYIFSFLKSFRNHNKFLLPDRAQVTM
EHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEECCCCCCEEE
TAPFMRSYSLKVIQTCHRRNAPAIGGMAAQIPIKNNPEANEAAFEKVRADKEREALDGHD
ECHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHCCCCC
GTWVAHPGLVPVAMEVFNHIMKTPNQIFRKREEICVTENDLLEVPVGTITEEGLRMNISV
CCEEECCCHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCEEECCCCCCCCCCEEEEHHH
GIQYIASWLSGRGAAPIYNLMEDAATAEISRAQVWQWIRHEGGKLNDGRNITLELMEELK
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
EEELAKIEREIGKEAFKKGRFQEATTLFTNLVRNDEFVPFLTLPGYEIL
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA