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The map label for this gene is ktrB [H]

Identifier: 218233954

GI number: 218233954

Start: 1386313

End: 1387656

Strand: Direct

Name: ktrB [H]

Synonym: BCB4264_A1442

Alternate gene names: 218233954

Gene position: 1386313-1387656 (Clockwise)

Preceding gene: 218235734

Following gene: 218232448

Centisome position: 25.58

GC content: 33.63

Gene sequence:

>1344_bases
ATGGACGTAACAAAAAAACAAGGGCTGTATAATCGTCTTATACGATTAAACCCACCACAAATATTAGCATTAGGCTTTTT
CTGCTTAATTGTGGTTGGCGGTTTGTTATTAAAATTACCATTCGCAACGAAAGTACATATTAGTTGGGTAGATGCTTTCT
TTACAGCAACGTCAGCAGCGACCGTAACTGGTTTGGGAGTAGTGGATACAGCAAGTACATTTACGATGTTTGGCGAAATT
GTTATTATGTTTTTAATTCAAACAGGTGGTCTAGGTCTTATGACAATTGCCATTTTAATTGTTTGGGTACTAGGTAAAAA
AATCGGATTACGCCATCGTTTATTAATTGGAGAAGCATTTAATCAAACAAATATAGGTGGTCTTGTAAAATTAGTAAAGC
GTGTCTTTATATTTTCGATTTGTATTGAACTTATTGGGGTCATCTTTTTATCGTTTCGCTTTATTCCAGAGTTTGGTTTT
GGAAAAGGTTTATATTATAGTATTTTTCATGTAATTGCATCTTATAATAATGCAGGATTTGCTTTATGGCCAGATAATTT
AACAAGATATGTAGGGGATCCCATTATTAATATTGGGATTTGCTCTTTAATTGTAATTGGGGGACTCGGTTTTACCGTAT
TAATTGATATATGGTATAGCCGCAGTTTTCGAAAATTATCACTTCACTCAAAAATAATGATTATTGGAACAGTAGTGCTA
AATGTTATAGCAATGATTGTAATTTTTGTATTGGAATATAATAATGTGAAGACGTTAGGGAATTTATCTTTAAATGAAAA
ACTATGGGCTTCCTTCTTTCAAGGTATTACTCCGCGGACAGCTGGATTTAATACGGTTGACTATGGAGGTATGGAAGAAT
CATCTATATTATTTACGATGATTTTAATGTTTATTGGTGCAGGAAGTGTATCGACAGGTGGAGGAATTAAATTAACGACG
TTTGTTATCTTAATTACATCTGTCCTTTCTTTCTTTAGAAAAAAGGAGGAAATTGTTTTATTTCAGCGTACAATTAAAAT
GTCGACAGTAACGAGGGCCTTAGCGATTGCTGTTGCCAGTCAAATACTTATTTTAGCAGCGGTATTCATATTAATGCTTA
CAGAAAACTTCAGCTTTATTCAATTATTATTTGAGACAATATCAGCGTTTGGCACAGTCGGATTAACGATGGGAATTACT
GCAAAGCTATCGGCATTCGGAAAATGTATTATTATGTTTGTTATGTTCTGCGGATTAATTGGACCATTAACACTTGTGTT
CTCTTTAGCGCGACCAGCAAAACAAAAAATAAAATATCCATCGGAAGATGTGTTTACAGGATAA

Upstream 100 bases:

>100_bases
TATTATGAGAATATAAGGTTTGTCCCAATTATTTAAGGGCTTTTAAAAAGCTTTTTATTGTATGAGGGGAAAGCTTCACT
TTAATAAGGGAGTTAGTGAT

Downstream 100 bases:

>100_bases
GGTATCCCGCGTTAAGCGAGATACCTTTTTCTTTTTTAGAACAGGGAGAACAATAGACCAATAAGTGCTACTCGGAATAA
AATTGCGATAAGTGCAGCAA

Product: potassium uptake protein, TrkH family

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: K(+)-uptake protein ktrB [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MDVTKKQGLYNRLIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIELIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIIGTVVL
NVIAMIVIFVLEYNNVKTLGNLSLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMILMFIGAGSVSTGGGIKLTT
FVILITSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILILAAVFILMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG

Sequences:

>Translated_447_residues
MDVTKKQGLYNRLIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIELIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIIGTVVL
NVIAMIVIFVLEYNNVKTLGNLSLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMILMFIGAGSVSTGGGIKLTT
FVILITSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILILAAVFILMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG
>Mature_447_residues
MDVTKKQGLYNRLIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAATVTGLGVVDTASTFTMFGEI
VIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAFNQTNIGGLVKLVKRVFIFSICIELIGVIFLSFRFIPEFGF
GKGLYYSIFHVIASYNNAGFALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIIGTVVL
NVIAMIVIFVLEYNNVKTLGNLSLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTMILMFIGAGSVSTGGGIKLTT
FVILITSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVASQILILAAVFILMLTENFSFIQLLFETISAFGTVGLTMGIT
AKLSAFGKCIIMFVMFCGLIGPLTLVFSLARPAKQKIKYPSEDVFTG

Specific function: Integral membrane subunit of the KtrAB potassium uptake transporter. The 2 major potassium transporter complexes KtrAB and KtrCD confer resistance to both suddenly imposed and prolonged osmotic stress [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family. Ktr (TC 2.A.38.4) subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 49038; Mature: 49038

Theoretical pI: Translated: 10.17; Mature: 10.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDVTKKQGLYNRLIRLNPPQILALGFFCLIVVGGLLLKLPFATKVHISWVDAFFTATSAA
CCCCHHCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHH
TVTGLGVVDTASTFTMFGEIVIMFLIQTGGLGLMTIAILIVWVLGKKIGLRHRLLIGEAF
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHCC
NQTNIGGLVKLVKRVFIFSICIELIGVIFLSFRFIPEFGFGKGLYYSIFHVIASYNNAGF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCE
ALWPDNLTRYVGDPIINIGICSLIVIGGLGFTVLIDIWYSRSFRKLSLHSKIMIIGTVVL
EECCHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
NVIAMIVIFVLEYNNVKTLGNLSLNEKLWASFFQGITPRTAGFNTVDYGGMEESSILFTM
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHH
ILMFIGAGSVSTGGGIKLTTFVILITSVLSFFRKKEEIVLFQRTIKMSTVTRALAIAVAS
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
QILILAAVFILMLTENFSFIQLLFETISAFGTVGLTMGITAKLSAFGKCIIMFVMFCGLI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GPLTLVFSLARPAKQKIKYPSEDVFTG
HHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]