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The map label for this gene is yisV [H]

Identifier: 218233761

GI number: 218233761

Start: 3764764

End: 3766197

Strand: Reverse

Name: yisV [H]

Synonym: BCB4264_A3856

Alternate gene names: 218233761

Gene position: 3766197-3764764 (Counterclockwise)

Preceding gene: 218234228

Following gene: 218231664

Centisome position: 69.5

GC content: 36.75

Gene sequence:

>1434_bases
ATGGAATGGAAACCAAATCGTGTAGATAAGACACCTGTATATAAACAAATTGCGGATTATATTGAAAGAGGCATTTCTTC
AGGGGAATTTCCTTCTGATAGTAAGTTACCTTCTGAGCGTATGTTAGCAAAGAAATTACAGGTGAACCGGAGTACAATAG
TAGCTGCGTATGAAGAATTAAAATCACTTGGAGTAGTAGAACGACAAAAGGGAAGCGGAACACGGGTCAATACAGACATA
TGGGGTGTCTCACATAAACGAATACCGAACTGGGGTAGGTACGTGGAGGATGGATCGTTCTTACCTAACGTACCACTCGT
TCAACAAATTCGAACGGAAACACAAAAAGATGATTTAATTAATTTAGCAAGTGGTGAACTGTCACCAGAATTAATTCCAA
GTGATAGATTTCGAACAATTTTGTCGGAGAAAACATTTATAGAAAATCTCGGCTATGACCATCCACTTGGAAATGAGATG
TTGAGAAAAACAATTGCAGCACATGTTCAGCAATATAAACAAATTGAAGCAGATTCAAGCTCTATTCTTATTACGTCTGG
AGCACAACAGGCGCTTAATCTTATCGTTCAATGTTTATTAAAACCTGGCGATGCGATTGCGATTGAAGATCCGTCATATT
GTTTTTCGCTTCCAATGTTTAAATCGGCCGGTTTAAACATATTTCATTTACCTGTTGATGAGCATGGAATGAATCCAGAT
GACTTAATCGATTTGCACAAAAAGCATCGCATTCGTATGGTATTTTTGAATCCAGATTATCAAAATCCAACAGGTACTGT
GCTTTCATTAGCGAGACGTAAAAAAATTTTAGAACTGTCTTCTGAGTTCGGTATACCAATTGTAGAAGATGATCCGTATA
GTTTAATTTCTTTTAATGGAGAAGTGAACCCGACATTAAAATCAATGGACCAAAATGGAAATGTTCTTTATATAAGTTCA
TTATCAAAAATTGTTGCATCAGGATTACGTATTGGATGGATAATTGGTCCTACACGTGTAATTGAGCGTTTAGCAGATGC
AAAGCAACAAGTTGATTTTGGCCATAGTGTATTTACGCAGTGGGTAGCAAATCAATTTTTAGAATCAAAGGATTTTCATA
CACATATTACGATACTTCGTGGACAATTGAAGCAAAGAAGAGATGAATTAATTGCAGAGCTTGAAGGAACATTGGGCGAC
CGAGTTGAATGTTTCGTGCCAGAGGGTGGAATACATGTATGGTGTAAAGTGAAAGGAAAGTTTGATGAATATCACTTATT
AGGTGAATCTATACGGAATGGTGTCGCATTTGTTCCGGGCAGTGTTTTAGGTTCGAAAAATGAATATATACGATTTACGT
TTGGTAGAGCGAATATAGAACAAATTCAACTTGGAATTAAACGGTTTGCCGACACGCTAAATGAAATTTCATAA

Upstream 100 bases:

>100_bases
TAGAAAGATTTTTAAATCATGTAATTAATTAATACTATTATTACAGTCAATACTGTTATTAGTGAGTAAAATATAGTTAG
TTTTGAGAGGGGGCAACTAT

Downstream 100 bases:

>100_bases
TATGGATGTGTGATAGTGAAATGAGGGAAAGAAATGAAGTACGTGATGCTTTTACTTCAAGTAGGCGTGCTATATATATT
TAGCTTAGTGGGTACGTGGA

Product: transcriptional regulator, GntR family/aminotransferase, class I protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MEWKPNRVDKTPVYKQIADYIERGISSGEFPSDSKLPSERMLAKKLQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFIENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSSSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLNIFHLPVDEHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLISFNGEVNPTLKSMDQNGNVLYISS
LSKIVASGLRIGWIIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESKDFHTHITILRGQLKQRRDELIAELEGTLGD
RVECFVPEGGIHVWCKVKGKFDEYHLLGESIRNGVAFVPGSVLGSKNEYIRFTFGRANIEQIQLGIKRFADTLNEIS

Sequences:

>Translated_477_residues
MEWKPNRVDKTPVYKQIADYIERGISSGEFPSDSKLPSERMLAKKLQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFIENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSSSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLNIFHLPVDEHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLISFNGEVNPTLKSMDQNGNVLYISS
LSKIVASGLRIGWIIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESKDFHTHITILRGQLKQRRDELIAELEGTLGD
RVECFVPEGGIHVWCKVKGKFDEYHLLGESIRNGVAFVPGSVLGSKNEYIRFTFGRANIEQIQLGIKRFADTLNEIS
>Mature_477_residues
MEWKPNRVDKTPVYKQIADYIERGISSGEFPSDSKLPSERMLAKKLQVNRSTIVAAYEELKSLGVVERQKGSGTRVNTDI
WGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLINLASGELSPELIPSDRFRTILSEKTFIENLGYDHPLGNEM
LRKTIAAHVQQYKQIEADSSSILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLNIFHLPVDEHGMNPD
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLISFNGEVNPTLKSMDQNGNVLYISS
LSKIVASGLRIGWIIGPTRVIERLADAKQQVDFGHSVFTQWVANQFLESKDFHTHITILRGQLKQRRDELIAELEGTLGD
RVECFVPEGGIHVWCKVKGKFDEYHLLGESIRNGVAFVPGSVLGSKNEYIRFTFGRANIEQIQLGIKRFADTLNEIS

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=432, Percent_Identity=28.7037037037037, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI33469970, Length=432, Percent_Identity=28.7037037037037, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI56713256, Length=320, Percent_Identity=23.4375, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI56713254, Length=320, Percent_Identity=23.4375, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1790797, Length=444, Percent_Identity=26.5765765765766, Blast_Score=151, Evalue=8e-38,
Organism=Escherichia coli, GI1787710, Length=465, Percent_Identity=24.5161290322581, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1788722, Length=336, Percent_Identity=25.8928571428571, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788627, Length=347, Percent_Identity=23.342939481268, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6321236, Length=393, Percent_Identity=24.6819338422392, Blast_Score=106, Evalue=9e-24,
Organism=Drosophila melanogaster, GI21356535, Length=391, Percent_Identity=22.2506393861893, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53715; Mature: 53715

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWKPNRVDKTPVYKQIADYIERGISSGEFPSDSKLPSERMLAKKLQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNTDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHE
NLASGELSPELIPSDRFRTILSEKTFIENLGYDHPLGNEMLRKTIAAHVQQYKQIEADSS
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLNIFHLPVDEHGMNPD
CEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLISFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECC
EVNPTLKSMDQNGNVLYISSLSKIVASGLRIGWIIGPTRVIERLADAKQQVDFGHSVFTQ
CCCHHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHH
WVANQFLESKDFHTHITILRGQLKQRRDELIAELEGTLGDRVECFVPEGGIHVWCKVKGK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGSKNEYIRFTFGRANIEQIQLGIKRFADTLNEIS
CHHHHHHHHHHHCCEEECCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEWKPNRVDKTPVYKQIADYIERGISSGEFPSDSKLPSERMLAKKLQVNRSTIVAAYEEL
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHH
KSLGVVERQKGSGTRVNTDIWGVSHKRIPNWGRYVEDGSFLPNVPLVQQIRTETQKDDLI
HHCCCEEECCCCCCEECCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHE
NLASGELSPELIPSDRFRTILSEKTFIENLGYDHPLGNEMLRKTIAAHVQQYKQIEADSS
ECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SILITSGAQQALNLIVQCLLKPGDAIAIEDPSYCFSLPMFKSAGLNIFHLPVDEHGMNPD
CEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCEEECCCHHHCCCEEEEECCHHCCCCHH
DLIDLHKKHRIRMVFLNPDYQNPTGTVLSLARRKKILELSSEFGIPIVEDDPYSLISFNG
HHHHHHCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEECC
EVNPTLKSMDQNGNVLYISSLSKIVASGLRIGWIIGPTRVIERLADAKQQVDFGHSVFTQ
CCCHHHHHCCCCCCEEEEHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHCCHHHHHH
WVANQFLESKDFHTHITILRGQLKQRRDELIAELEGTLGDRVECFVPEGGIHVWCKVKGK
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEEECC
FDEYHLLGESIRNGVAFVPGSVLGSKNEYIRFTFGRANIEQIQLGIKRFADTLNEIS
CHHHHHHHHHHHCCEEECCCHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]