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The map label for this gene is mgtB [H]

Identifier: 218233592

GI number: 218233592

Start: 1558463

End: 1559188

Strand: Direct

Name: mgtB [H]

Synonym: BCB4264_A1642

Alternate gene names: 218233592

Gene position: 1558463-1559188 (Clockwise)

Preceding gene: 218235271

Following gene: 218233992

Centisome position: 28.76

GC content: 34.16

Gene sequence:

>726_bases
ATGTTATATGCAAACAAAACTGTGGGTAACACGTCATATAAACTAAGTAAAAAATCAATAAAAGAACAAACAATGCTCCA
AAAAAATAAAGATTTATTAATTGAAATTGCAACAAGAGATGTAAAATCTGTATTTGCATATTTTAAAACAACAAGAGACG
GACTATCAATGAAAGAGGCACAAAAACGTATTCAAGTATATGGCCGAAATGAACTAACTTCAAAAAGAGCACTTCTCGCA
GAAGTAATGATGAAGCTTGGTGGCATGATTCCAGGTTTTTCAAAACAACGTGTGTGTGATGAATTACAACGTGAAACGAT
TACTGTATCTAGAGTAGAATGTTCTAGTAGTACAGGGCTAAATAGTGAACTGAAAATGATGGAGATACCAGTGCAAGAAC
TTGTACCTGGAGATATAATTTTTCTTTCGGCTGGAGATGCTGTGCCAGCTGATGTACGTATTATTTATGCAGATGATTTA
TTAGTGAATGAGTCTGTGTTAACGGGAAACGAAGCGAATATAGAGAAGTTTGAAAGCTGCTATCACCTTGAACGTAAACG
ATTTATTCCATTAAAACGGATGAAAGATTATAATCCACTTGAGCTTGAAAATGTATGTTTTAAAGGTTCACATATCGTTA
GTGGAAATGCAAAGGCTGTCGTTGTTTCTACTGGAAAAAATACGTATTCAGGCATATTGCATACTTGTTGTAGTAGAACG
TCTTAA

Upstream 100 bases:

>100_bases
ATAATGTAGCGTTTATAAAACGCGAGACACTTTCACAGTAAAGTGGATAAATTGAGAAACAAAGCGTTTCTTCCTATGTT
GTAAAGGAGGAGACGATAAT

Downstream 100 bases:

>100_bases
TGTGTTAATGGTGCTAAATATACAAAAACAATGTATAATAGACAAAGTTGAGCAAAAACGTAGAATGGTAATCTATTTAT
ATAACCTTACGTGATAACGT

Product: putative cation transporter

Products: NA

Alternate protein names: Mg(2+) transport ATPase, P-type 1 [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MLYANKTVGNTSYKLSKKSIKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRALLA
EVMMKLGGMIPGFSKQRVCDELQRETITVSRVECSSSTGLNSELKMMEIPVQELVPGDIIFLSAGDAVPADVRIIYADDL
LVNESVLTGNEANIEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGSHIVSGNAKAVVVSTGKNTYSGILHTCCSRT
S

Sequences:

>Translated_241_residues
MLYANKTVGNTSYKLSKKSIKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRALLA
EVMMKLGGMIPGFSKQRVCDELQRETITVSRVECSSSTGLNSELKMMEIPVQELVPGDIIFLSAGDAVPADVRIIYADDL
LVNESVLTGNEANIEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGSHIVSGNAKAVVVSTGKNTYSGILHTCCSRT
S
>Mature_241_residues
MLYANKTVGNTSYKLSKKSIKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEAQKRIQVYGRNELTSKRALLA
EVMMKLGGMIPGFSKQRVCDELQRETITVSRVECSSSTGLNSELKMMEIPVQELVPGDIIFLSAGDAVPADVRIIYADDL
LVNESVLTGNEANIEKFESCYHLERKRFIPLKRMKDYNPLELENVCFKGSHIVSGNAKAVVVSTGKNTYSGILHTCCSRT
S

Specific function: Mediates magnesium influx to the cytosol [H]

COG id: COG0474

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIB subfamily [H]

Homologues:

Organism=Homo sapiens, GI153946397, Length=108, Percent_Identity=37.037037037037, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI118498343, Length=109, Percent_Identity=35.7798165137615, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI22748667, Length=112, Percent_Identity=35.7142857142857, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI4502271, Length=115, Percent_Identity=33.9130434782609, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI2367363, Length=108, Percent_Identity=44.4444444444444, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24668704, Length=254, Percent_Identity=26.7716535433071, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI17136664, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24762455, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762453, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762447, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762457, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762449, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762445, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24762451, Length=111, Percent_Identity=35.1351351351351, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161085803, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668708, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281366617, Length=100, Percent_Identity=38, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24668696, Length=100, Percent_Identity=38, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006068
- InterPro:   IPR004014
- InterPro:   IPR001757
- InterPro:   IPR006415
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00689 Cation_ATPase_C; PF00690 Cation_ATPase_N; PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.2 [H]

Molecular weight: Translated: 26991; Mature: 26991

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLYANKTVGNTSYKLSKKSIKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEA
CCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
QKRIQVYGRNELTSKRALLAEVMMKLGGMIPGFSKQRVCDELQRETITVSRVECSSSTGL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCC
NSELKMMEIPVQELVPGDIIFLSAGDAVPADVRIIYADDLLVNESVLTGNEANIEKFESC
CCCHHEEECCHHHHCCCCEEEEECCCCCCCCEEEEEECCEEECCCEECCCCCCHHHHHHH
YHLERKRFIPLKRMKDYNPLELENVCFKGSHIVSGNAKAVVVSTGKNTYSGILHTCCSRT
HHHHHHHCCCHHHCCCCCCCCHHHEEECCCEEECCCCCEEEEECCCCHHHHHHHHHHCCC
S
C
>Mature Secondary Structure
MLYANKTVGNTSYKLSKKSIKEQTMLQKNKDLLIEIATRDVKSVFAYFKTTRDGLSMKEA
CCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCHHHH
QKRIQVYGRNELTSKRALLAEVMMKLGGMIPGFSKQRVCDELQRETITVSRVECSSSTGL
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHEEEEEEEEECCCCCC
NSELKMMEIPVQELVPGDIIFLSAGDAVPADVRIIYADDLLVNESVLTGNEANIEKFESC
CCCHHEEECCHHHHCCCCEEEEECCCCCCCCEEEEEECCEEECCCEECCCCCCHHHHHHH
YHLERKRFIPLKRMKDYNPLELENVCFKGSHIVSGNAKAVVVSTGKNTYSGILHTCCSRT
HHHHHHHCCCHHHCCCCCCCCHHHEEECCCEEECCCCCEEEEECCCCHHHHHHHHHHCCC
S
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1824701; 11677609; 7751273 [H]