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The map label for this gene is hlgB [H]

Identifier: 218233534

GI number: 218233534

Start: 1131865

End: 1132875

Strand: Reverse

Name: hlgB [H]

Synonym: BCB4264_A1163

Alternate gene names: 218233534

Gene position: 1132875-1131865 (Counterclockwise)

Preceding gene: 218234258

Following gene: 218235081

Centisome position: 20.91

GC content: 36.2

Gene sequence:

>1011_bases
ATGAAACGTTCTAAAACATACTTAAAATGTTTAGCATTATCCGCTGTTTTTGCTAGTAGCGCTGTAACTCTTTCAACACC
TGCTGCTTACGCTCAAACGACGTCACAAGTTGTAACAGATATCGGGCAAAATGCAAAAACACATACGAGCTATAATACAT
TTAATAATGATCAAGCTGATAATATGACAATGTCTTTAAAGGTAACTTTTATCGATGATCCGAGCGCTGATAAACAGATT
GCCGTTATTAATACAACTGGTAGTTTTCTAAAAGCAAATCCTACTATAAGTGATGCACCTATTGATAACTACCCAATCCC
TGGTGCTAGTGCAACATTACGTTATCCTTCACAATATGATGTTGCATTTAACCTTCAAGATAACAGCGCTCGTTTCTTTA
ACGTAGCACCTACAAATGCTGTAGAAGAAACGACTGTAACATCTAGCGTATCTTATCAACTTGGTGGCTCTGTTAAAGCT
TCTGTAACGCCTAATGGACCTAGCGGTGAAGCTGGTGCAACTGGTCAAGTCACTTGGTCTGACTCTGTAAGCTATAAACA
AACTAGTTATAAAACAAATTTAATTGACCAAACGAACAAAAACGTAAAATGGAACGTATTCTTTAACGGATATAACAATC
AAAACTGGGGTATTTACACACGTGACTCCTATCATTCTTTATATGGAAACCAACTTTTCATGTACTCTCGCACATACCTA
TATGAATCTGATGCAAAAGGTAATTTAATACCGATGGATCAACTTCCAGCATTAACAAATAGCGGTTTCTCTCCTGGTAT
GATTGCTGTTGTTATCTCTGAAAAAAATACAGATCAATCTAACTTACAAGTCGCTTATACAAAACACGCCGATGACTACC
AACTTCGTCCAGGCTTCACATTCGGAACTGCAAACTGGGTTGGAAACAACGTAAAAGACGTTGATCAAAAAACATTTAAT
AAATCATTTACACTAGATTGGAAGAATAAAAAGTTAGTAGAGAAAAAATAA

Upstream 100 bases:

>100_bases
ATCTATGCAATTATGCATAACCATCCATTCCGTTTTATTTTCATGTTACGATATAAATGTAATACGACATATATCGACAA
AGATAAAAGGAAGTGATTGT

Downstream 100 bases:

>100_bases
AGTAAAACTTTAATGAGTGGGGGGCTTCATCCCCTACTCATTATTTTATTAGTTAAATCAATCGGGTATTAACTGGTATT
TTAAAATTTCACATGTTATA

Product: cytotoxin K

Products: NA

Alternate protein names: H-gamma-1; H-gamma-I [H]

Number of amino acids: Translated: 336; Mature: 336

Protein sequence:

>336_residues
MKRSKTYLKCLALSAVFASSAVTLSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQADNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISDAPIDNYPIPGASATLRYPSQYDVAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SVTPNGPSGEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGFTFGTANWVGNNVKDVDQKTFN
KSFTLDWKNKKLVEKK

Sequences:

>Translated_336_residues
MKRSKTYLKCLALSAVFASSAVTLSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQADNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISDAPIDNYPIPGASATLRYPSQYDVAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SVTPNGPSGEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGFTFGTANWVGNNVKDVDQKTFN
KSFTLDWKNKKLVEKK
>Mature_336_residues
MKRSKTYLKCLALSAVFASSAVTLSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQADNMTMSLKVTFIDDPSADKQI
AVINTTGSFLKANPTISDAPIDNYPIPGASATLRYPSQYDVAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKA
SVTPNGPSGEAGATGQVTWSDSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGFTFGTANWVGNNVKDVDQKTFN
KSFTLDWKNKKLVEKK

Specific function: Toxin that seems to act by forming pores in the membrane of the cell. Has a hemolytic and a leucotoxic activity [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aerolysin family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003963
- InterPro:   IPR001340
- InterPro:   IPR016183 [H]

Pfam domain/function: PF07968 Leukocidin [H]

EC number: NA

Molecular weight: Translated: 37004; Mature: 37004

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRSKTYLKCLALSAVFASSAVTLSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQAD
CCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NMTMSLKVTFIDDPSADKQIAVINTTGSFLKANPTISDAPIDNYPIPGASATLRYPSQYD
CEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCEE
VAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKASVTPNGPSGEAGATGQVTWS
EEEEEECCCCEEEEECCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCEEEEEC
DSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
CCCCEEECCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEEEEEEE
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGFT
EECCCCCCEEEHHHCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCEE
FGTANWVGNNVKDVDQKTFNKSFTLDWKNKKLVEKK
EECHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MKRSKTYLKCLALSAVFASSAVTLSTPAAYAQTTSQVVTDIGQNAKTHTSYNTFNNDQAD
CCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
NMTMSLKVTFIDDPSADKQIAVINTTGSFLKANPTISDAPIDNYPIPGASATLRYPSQYD
CEEEEEEEEEECCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEECCCCEE
VAFNLQDNSARFFNVAPTNAVEETTVTSSVSYQLGGSVKASVTPNGPSGEAGATGQVTWS
EEEEEECCCCEEEEECCCCCCCCCEEEEEEEEEECCCEEEEECCCCCCCCCCCCEEEEEC
DSVSYKQTSYKTNLIDQTNKNVKWNVFFNGYNNQNWGIYTRDSYHSLYGNQLFMYSRTYL
CCCCEEECCEEECCCCCCCCCEEEEEEECCCCCCCCEEEECCCHHHHCCCEEEEEEEEEE
YESDAKGNLIPMDQLPALTNSGFSPGMIAVVISEKNTDQSNLQVAYTKHADDYQLRPGFT
EECCCCCCEEEHHHCCHHHCCCCCCCEEEEEEECCCCCCCCEEEEEEECCCCEEECCCEE
FGTANWVGNNVKDVDQKTFNKSFTLDWKNKKLVEKK
EECHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA