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The map label for this gene is yjdA [H]

Identifier: 218233382

GI number: 218233382

Start: 3218246

End: 3219019

Strand: Reverse

Name: yjdA [H]

Synonym: BCB4264_A3339

Alternate gene names: 218233382

Gene position: 3219019-3218246 (Counterclockwise)

Preceding gene: 218232799

Following gene: 218231171

Centisome position: 59.4

GC content: 39.79

Gene sequence:

>774_bases
ATGGAGGAGAAAAAGGTGAAGAAAATAGCAATTGTAACAGGGGCAACTCGTCTGAATGGAATTGGTGCAGCTGTATGCAA
GGTGCTTGCTCAAAAAGGGATAGACATTTTTTTCACGTACTGGCCAAAGTATGATAAAGCGATGCCATGGGGAATGAGTG
ATCAAGAACCCTTTTTGCTGAAAAAGGAAATTGAAAGTTACGATGTTCGATGTGAAATGGCAGAAATCAATTTATCGCAG
TCTTATTCGCCAAATCGTTTGTTTTATATGGTATCAGAACGGTTAGGTGATCCATCTATTCTAGTTAATAATGCAGTATA
TTCTACTCATACGAGAATTGAGGAATTAGATGTAGAGCAGTTGGATAAACATTATACAGTTAATGTTCGGGCTACTATGC
TATTAAGTTCATTGTTTATAAAACATTATTCACTTAAAACGGGCGGGAGTATTATTAATCTTACTTCAGGACAGTCAGTA
GGTCCAATGCCAGATGAACTAGCATATGCAGCAACGAAAGGGGCAATTGAAGCATTTACAAAGTCAGTAGCACCAGTTGC
GATGGAGAAGGGGATTACAGTGAATGCTGTAGATCCAGGACCGACGAATACAGGATGGATTACAGAGGAGCTGAAGCATC
ATTTAGTATGGAAGTTCCCGCAAGGTAAAGTAGGAGAACCGGTGGATGCTGCGCGCTTAATTTCTTTTTTAGTAAGTGAA
GAAGCGAAATGGGTTACTGGGCAAGTCATTCACTCGAATGGTGGTTATTCATAA

Upstream 100 bases:

>100_bases
TATCTTTATTAAAATGTTAAAATTAGGTGCTGAACGTATACTGTCAAATATTCAATAAGAAGATAGATCCTCTGTATTCA
TGCAGGGGATCTGTGTATAG

Downstream 100 bases:

>100_bases
AAATATTATGTTAACAAATGTTGAGAAACAAAAAACGAAAGAAAATTTTATTTTTTTGTATAAATAAAATGTCAAGAAAG
ATAAAAATTTGATAGAAGAG

Product: 3-ketoacyl-(acyl-carrier-protein) reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MEEKKVKKIAIVTGATRLNGIGAAVCKVLAQKGIDIFFTYWPKYDKAMPWGMSDQEPFLLKKEIESYDVRCEMAEINLSQ
SYSPNRLFYMVSERLGDPSILVNNAVYSTHTRIEELDVEQLDKHYTVNVRATMLLSSLFIKHYSLKTGGSIINLTSGQSV
GPMPDELAYAATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSE
EAKWVTGQVIHSNGGYS

Sequences:

>Translated_257_residues
MEEKKVKKIAIVTGATRLNGIGAAVCKVLAQKGIDIFFTYWPKYDKAMPWGMSDQEPFLLKKEIESYDVRCEMAEINLSQ
SYSPNRLFYMVSERLGDPSILVNNAVYSTHTRIEELDVEQLDKHYTVNVRATMLLSSLFIKHYSLKTGGSIINLTSGQSV
GPMPDELAYAATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSE
EAKWVTGQVIHSNGGYS
>Mature_257_residues
MEEKKVKKIAIVTGATRLNGIGAAVCKVLAQKGIDIFFTYWPKYDKAMPWGMSDQEPFLLKKEIESYDVRCEMAEINLSQ
SYSPNRLFYMVSERLGDPSILVNNAVYSTHTRIEELDVEQLDKHYTVNVRATMLLSSLFIKHYSLKTGGSIINLTSGQSV
GPMPDELAYAATKGAIEAFTKSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSE
EAKWVTGQVIHSNGGYS

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=255, Percent_Identity=27.4509803921569, Blast_Score=85, Evalue=8e-17,
Organism=Homo sapiens, GI40254992, Length=250, Percent_Identity=25.6, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI66933014, Length=175, Percent_Identity=28.5714285714286, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788459, Length=255, Percent_Identity=29.8039215686275, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=28.3464566929134, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=30.5555555555556, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI2367175, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082100, Length=268, Percent_Identity=25.7462686567164, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082160, Length=254, Percent_Identity=27.5590551181102, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789208, Length=255, Percent_Identity=26.2745098039216, Blast_Score=67, Evalue=9e-13,
Organism=Escherichia coli, GI1786812, Length=257, Percent_Identity=25.6809338521401, Blast_Score=65, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=268, Percent_Identity=28.3582089552239, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17562906, Length=266, Percent_Identity=27.8195488721804, Blast_Score=87, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI115534694, Length=253, Percent_Identity=25.6916996047431, Blast_Score=86, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=27.037037037037, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=272, Percent_Identity=29.7794117647059, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=266, Percent_Identity=27.8195488721804, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=254, Percent_Identity=25.5905511811024, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=27.1375464684015, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25147288, Length=259, Percent_Identity=28.957528957529, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=271, Percent_Identity=27.6752767527675, Blast_Score=74, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=259, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=256, Percent_Identity=25.78125, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=269, Percent_Identity=24.5353159851301, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=269, Percent_Identity=26.3940520446097, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=25.4826254826255, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=199, Percent_Identity=27.6381909547739, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=262, Percent_Identity=25.1908396946565, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=24.9056603773585, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17508651, Length=197, Percent_Identity=28.9340101522843, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=200, Percent_Identity=28, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=271, Percent_Identity=25.4612546125461, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=264, Percent_Identity=23.8636363636364, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17561272, Length=195, Percent_Identity=26.1538461538462, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17544670, Length=188, Percent_Identity=28.1914893617021, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI23397609, Length=258, Percent_Identity=28.6821705426357, Blast_Score=104, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24639444, Length=259, Percent_Identity=28.957528957529, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355319, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21357041, Length=260, Percent_Identity=31.1538461538462, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=29.1187739463602, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28571526, Length=169, Percent_Identity=33.1360946745562, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24643142, Length=258, Percent_Identity=27.5193798449612, Blast_Score=70, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24644337, Length=116, Percent_Identity=36.2068965517241, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 28447; Mature: 28447

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEKKVKKIAIVTGATRLNGIGAAVCKVLAQKGIDIFFTYWPKYDKAMPWGMSDQEPFLL
CCCHHEEEEEEEECCHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHH
KKEIESYDVRCEMAEINLSQSYSPNRLFYMVSERLGDPSILVNNAVYSTHTRIEELDVEQ
HHHHHCCCEEEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEEECCEEHHHHHHHHCCHHH
LDKHYTVNVRATMLLSSLFIKHYSLKTGGSIINLTSGQSVGPMPDELAYAATKGAIEAFT
HCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
KSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSE
HHHCCHHHHCCCEEEECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHC
EAKWVTGQVIHSNGGYS
CCCEEEEEEEECCCCCC
>Mature Secondary Structure
MEEKKVKKIAIVTGATRLNGIGAAVCKVLAQKGIDIFFTYWPKYDKAMPWGMSDQEPFLL
CCCHHEEEEEEEECCHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHH
KKEIESYDVRCEMAEINLSQSYSPNRLFYMVSERLGDPSILVNNAVYSTHTRIEELDVEQ
HHHHHCCCEEEEEEEECCCCCCCCCEEEEEEHHHCCCCCEEEECCEEHHHHHHHHCCHHH
LDKHYTVNVRATMLLSSLFIKHYSLKTGGSIINLTSGQSVGPMPDELAYAATKGAIEAFT
HCCEEEEEHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHH
KSVAPVAMEKGITVNAVDPGPTNTGWITEELKHHLVWKFPQGKVGEPVDAARLISFLVSE
HHHCCHHHHCCCEEEECCCCCCCCCCHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHC
EAKWVTGQVIHSNGGYS
CCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]